Understanding how some pancreatic cancer patients respond well to treatments
The Memorial Sloan Kettering Cancer Center SPORE in Pancreas Cancer
This study is looking at how certain genes and molecules affect how well patients with advanced pancreatic cancer respond to different treatments, with the hope of finding ways to improve care and survival for everyone facing this tough disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10908413 on NIH RePORTER |
What this research studies
This research investigates the genetic and molecular factors that contribute to exceptional responses to therapies in patients with pancreatic ductal adenocarcinoma (PDAC). By analyzing both standard and immune-based treatments, the project aims to identify mechanisms of resistance and sensitivity to these therapies. The goal is to use this knowledge to guide clinical management and improve survival rates for all patients with pancreatic cancer. The research will focus on advanced stages of the disease, where treatment options are most critical.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with locally advanced or metastatic pancreatic ductal adenocarcinoma.
Not a fit: Patients with early-stage pancreatic cancer or those with other types of cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment strategies for pancreatic cancer, potentially improving survival rates.
How similar studies have performed: Previous research has shown promising results in understanding treatment responses in pancreatic cancer, indicating potential for success in this approach.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: O'reilly, Eileen Mary — Sloan-Kettering Inst Can Research
- Study coordinator: O'reilly, Eileen Mary
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.