Understanding how pancreatic cancer spreads
Investigating the metastatic drive in pancreas cancer
['FUNDING_R01'] · UNIVERSITY OF NEBRASKA MEDICAL CENTER · NIH-10757574
This study is looking into how pancreatic cancer spreads aggressively, using special mouse models that act like human cases, to find ways to create better treatments that could help patients live longer and healthier lives.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF NEBRASKA MEDICAL CENTER (nih funded) |
| Locations | 1 site (OMAHA, UNITED STATES) |
| Trial ID | NIH-10757574 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms behind the aggressive spread of pancreatic cancer, which significantly impacts patient survival. By using genetically engineered mouse models that mimic human disease, the study aims to identify how certain factors influence tumor growth and metastasis. The goal is to improve treatment strategies by tailoring systemic and local therapies based on the specific characteristics of the cancer. Patients may benefit from insights that could lead to more effective therapies and improved outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with pancreatic cancer, particularly those with aggressive or metastatic forms of the disease.
Not a fit: Patients with non-cancerous conditions or those with early-stage pancreatic cancer that does not exhibit aggressive characteristics may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment strategies for pancreatic cancer, potentially prolonging survival for patients.
How similar studies have performed: Other research has shown promise in understanding cancer metastasis through similar approaches, indicating that this line of investigation could yield valuable insights.
Where this research is happening
OMAHA, UNITED STATES
- UNIVERSITY OF NEBRASKA MEDICAL CENTER — OMAHA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HINGORANI, SUNIL R — UNIVERSITY OF NEBRASKA MEDICAL CENTER
- Study coordinator: HINGORANI, SUNIL R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.