Condition

Pancreas Adenocarcinoma clinical trials and research

• 21Clinical trials
• 9Countries

Newest Pancreas Adenocarcinoma clinical trials

All recruiting trials (21)

• Hepatic artery infusion therapy for liver metastases after pancreatic/duodenal cancer surgery

  This study tests whether delivering chemotherapy directly to the liver via a pump can help people with pancreatic or duodenal cancer that has spread mainly to the liver after surgery and prior chemotherapy.

  Recruiting AdventHealth · Orlando, Florida · NCT07845617

• Liquid biopsy biomarkers to detect and monitor pancreatic cancer

  Researchers test blood-based microRNA signals to see if they can identify pancreatic cancer risk or early disease in people with familial or hereditary risk or mucinous cysts.

  Recruiting Università Vita-Salute San Raffaele · Milan, MI · NCT07700992

• THE-0504 in patients with solid tumors

  A first-in-human, dose-escalation study to see if THE-0504 is safe and tolerable in adults with solid tumors such as SCLC, CRC, GC, TNBC, and pancreatic cancer.

  Recruiting Phase 1 Thena Biotech S.r.l. · Rome, Lazio · NCT07646106

• Planned surgery or focused local treatment after chemo for metastatic upper-GI adenocarcinoma with undetectable ctDNA

  This test sees if adding planned surgery or local treatments after three months of chemotherapy helps people with metastatic upper-gastrointestinal adenocarcinomas who have undetectable ctDNA.

  Recruiting Phase 2 Yale University · New Haven, Connecticut · NCT07282912

• Preventing complications after high-risk Whipple (pancreatoduodenectomy) with hydrocortisone, octreotide, and a teres ligament patch

  This tests whether giving hydrocortisone and octreotide around surgery plus placing a teres ligament patch can lower major complications after Whipple surgery in patients with a small pancreatic duct.

  Recruiting Phase 4 Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Amsterdam · NCT07262957

• Neoadjuvant chemotherapy versus immediate surgery for resectable pancreatic head and periampullary cancer

  This trial tests if giving chemotherapy before surgery helps people with resectable pancreatic head or periampullary cancer live longer than having immediate surgery followed by chemotherapy.

  Recruiting Phase 3 Minia University · Minya, Minya Governorate · NCT07081360

• Alternating gemcitabine + nab-paclitaxel and modified FOLFIRINOX for borderline resectable pancreatic cancer

  This trial will try alternating two chemotherapy regimens, gemcitabine with nab-paclitaxel and modified FOLFIRINOX, before surgery for people with borderline resectable pancreatic adenocarcinoma.

  Recruiting Phase 2 Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT07043270

• Predicting pancreatic fistula after pancreaticoduodenectomy

  This project will try to find which before-, during-, and after-surgery factors predict clinically significant pancreatic fistula in adults having pancreaticoduodenectomy for pancreatic or periampullary tumors.

  Recruiting Minia University · Minya · NCT07022015

• Testing ZM008 alone and with Pembrolizumab in patients with advanced solid tumors

  This study is testing a new treatment called ZM008, alone and with another drug called Pembrolizumab, to see if it can help patients with advanced solid tumors who have run out of other treatment options.

  Recruiting at 3 sites Phase 1 Zumutor Biologics Inc. · Boston, Massachusetts and 2 other locations · NCT06451497

• Surgery for pancreatic cancer with liver metastases after chemotherapy

  This study is testing whether surgery after chemotherapy can help people with pancreatic cancer that has spread to the liver live longer and have better outcomes.

  Recruiting Laval University · Québec, Quebec · NCT06349278

• Analyzing long-term survivors of aggressive solid tumors

  This study looks at patients who have survived much longer than expected from aggressive solid tumors to see what makes them different and if it can help develop new treatments.

  Recruiting Cure 51 · Villejuif · NCT06160596

• Investigating lymph node metastasis in pancreatic cancer surgery

  This study is testing whether removing certain lymph nodes during pancreatic cancer surgery can help doctors understand how the cancer spreads and improve treatment for patients.

  Recruiting at 2 sites Uppsala University Hospital · Odense and 5 other locations · NCT06065891

• Using technology to improve care for pancreatic cancer patients

  This study is trying to see if sharing patient data among hospitals can help improve care and outcomes for people with pancreatic cancer.

  Recruiting UMC Utrecht · Utrecht · NCT06055010

• Fluorescence-guided surgery for pancreatic cancer

  This study is testing a special imaging technique to help surgeons see pancreatic tumors better during surgery for patients who have had treatment before their operation.

  Recruiting Phase 2 Leiden University Medical Center · Leiden · NCT05984810

• Chemotherapy sequence for pancreatic cancer treatment

  This study is testing a new order of chemotherapy drugs to see if it helps people with hard-to-treat pancreatic cancer have their tumors completely removed through surgery.

  Recruiting at 2 sites Phase 2 Wake Forest University Health Sciences · Charlotte, North Carolina and 1 other locations · NCT05825066

• Exploring genetic factors linked to cancer cachexia in pancreatic cancer patients

  This study is trying to see if certain genetic factors are linked to weight loss and muscle wasting in patients with advanced pancreatic cancer.

  Recruiting at 2 sites Wake Forest University Health Sciences · Charlotte, North Carolina and 1 other locations · NCT05376592

• Assessing survival and quality of life in patients with advanced pancreatic cancer

  This study looks at how long people with advanced pancreatic cancer live and how their quality of life is affected while being treated at different hospitals in the Nordic region.

  Recruiting Umeå University · Umeå · NCT05356039

• Using Cyberknife to treat borderline resectable or locally advanced pancreatic cancer

  This study is testing if a special type of radiation therapy called Cyberknife can help people with tough-to-treat pancreatic cancer shrink their tumors enough to consider surgery.

  Recruiting Capital Health System, Inc · Pennington, New Jersey · NCT04998552

• Registry for patients with pancreatic ductal adenocarcinoma

  This study is collecting information from people newly diagnosed with pancreatic cancer to help improve understanding and treatment of the disease.

  Recruiting University of Ulm · Ulm · NCT04099134

• Evaluating tumor types in pancreatic cancer patients receiving FOLFIRINOX treatment

  This study is testing how different types of pancreatic cancer respond to the chemotherapy FOLFIRINOX before surgery to see if it helps make the tumors easier to remove.

  Recruiting Phase 2 UNC Lineberger Comprehensive Cancer Center · Chapel Hill, North Carolina · NCT03977233

• Combining chemotherapy and radiation before surgery for localized pancreatic cancer

  This study is testing if giving chemotherapy and radiation before surgery can help people with localized pancreatic cancer have better chances of completely removing the cancer.

  Recruiting Phase 2 Loma Linda University · Loma Linda, California · NCT03492671

Related topics

Quick answers

How many Pancreas Adenocarcinoma clinical trials are recruiting right now?

21, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (9 trials), Netherlands (3 trials), Egypt (2 trials), Italy (2 trials), Sweden (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 1: 2, Phase 3: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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