Finding ways to improve treatment for pancreatic cancer
OVERCOMING STROMAL BARRIERS TO THERAPEUTICS IN PANCREAS CANCER
This study is looking at how the environment around pancreatic cancer cells affects their growth and spread, with the goal of finding better treatments that could help patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project ID | NIH-11094151 on NIH RePORTER |
What this research studies
This research investigates the complex biology of pancreatic ductal adenocarcinomas (PDAs), which are highly lethal cancers. It focuses on understanding how the tumor environment, including various non-cancerous cells and proteins, contributes to the growth and spread of the cancer. By using genetically engineered animal models that mimic human disease, the research aims to identify new strategies to overcome barriers that prevent effective treatment. Patients may benefit from insights that could lead to improved therapies targeting these tumors.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with pancreatic ductal adenocarcinoma or those at high risk for developing this type of cancer.
Not a fit: Patients with other types of cancer or those without pancreatic cancer may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for pancreatic cancer, potentially improving survival rates.
How similar studies have performed: Previous research has shown promise in understanding tumor biology and developing targeted therapies, suggesting that this approach could yield significant advancements.
Where this research is happening
Omaha, United States
- University of Nebraska Medical Center — Omaha, United States (Active)
Researchers
- Principal investigator: Hingorani, Sunil R — University of Nebraska Medical Center
- Study coordinator: Hingorani, Sunil R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.