ovarian cancer Clinical Trials and Research
Also known as: ovarian carcinoma, oc, epithelial ovarian cancer, fallopian tube cancer, primary peritoneal cancer, gynecologic cancer · ICD-10: C56
Ovarian cancer occurs when abnormal cells grow in the ovaries, which are part of the female reproductive system. Clinical trial research is actively exploring new therapies, improved diagnostic methods, and ways to prevent recurrence. Find a Trial helps patients search for active studies.
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Common questions about ovarian cancer clinical trials
Who can participate in ovarian cancer clinical trials?
Eligibility criteria vary by study, often including factors like cancer stage, previous treatments, age, and overall health. These criteria ensure patient safety and that the study can effectively answer its research questions, as reported on ClinicalTrials.gov.
What are the different phases of clinical trials for ovarian cancer?
Clinical trials typically progress through phases 1, 2, and 3. Phase 1 studies focus on safety, phase 2 on effectiveness, and phase 3 compare new treatments to existing ones, as described on ClinicalTrials.gov.
What are some current research directions for ovarian cancer treatments?
Current research for ovarian cancer explores targeted therapies, immunotherapies, and new chemotherapy combinations to improve outcomes. Studies also investigate novel surgical techniques and drug delivery methods, according to NIH RePORTER.
What types of interventions are common in ovarian cancer trials?
Interventions in ovarian cancer trials often include new drugs, such as PARP inhibitors or anti-angiogenic agents, and various chemotherapy regimens. Surgical approaches and radiation therapy techniques are also studied, as seen on ClinicalTrials.gov.
Are there specific biomarkers important in ovarian cancer clinical trials?
Yes, biomarkers like BRCA1/2 mutations, HRD (homologous recombination deficiency), and CA-125 levels are often important in ovarian cancer trials. These help identify patients who might respond to specific targeted therapies, according to NIH RePORTER.
Do clinical trials for ovarian cancer cost money to participate?
Generally, study-related medical costs for clinical trial participation are covered by the trial sponsor. However, routine care costs and travel expenses may not be, so it's important to clarify with the study team, as noted on ClinicalTrials.gov.
What are common reasons someone might be excluded from an ovarian cancer trial?
Common exclusion criteria for ovarian cancer trials include certain prior treatments, other active cancers, or significant co-existing medical conditions. Specific organ function levels or pregnancy are also often reasons for exclusion, based on ClinicalTrials.gov data.
Is there research on early detection methods for ovarian cancer?
Yes, research is ongoing to develop better early detection methods for ovarian cancer, which is often diagnosed at advanced stages. Studies investigate new blood tests, imaging techniques, and genetic screening approaches, as reported by NIH RePORTER.
How to find a ovarian cancer trial that fits you
- Describe your ovarian cancer situation in detail — stage if applicable, prior treatments, age, and other relevant conditions.
- Use the location filter (worldwide, US, US & Canada, Europe) to narrow to trials near you.
- Review each trial's eligibility criteria carefully. Save 2–5 candidates with their NCT numbers.
- Discuss with your treating clinician before contacting the research site.
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