Cutting down ultra-processed foods for people at high cancer risk
Impact of a Mixed Intervention Aiming to Decrease the Consumption of Ultra-processed Foods on the Global Diet Quality in Individuals at High Risk of Cancer
This project tests whether using the Open Food Facts smartphone app alongside nutrition education helps adults at high risk of cancer eat fewer ultra-processed foods.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 170 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Gustave Roussy, Cancer Campus, Grand Paris Academic / other |
| Locations | 3 sites (Avignon and 2 other locations) |
| Trial ID | NCT07436312 on ClinicalTrials.gov |
What this trial studies
The U-TRANS program enrolls adults at increased cancer risk with a low baseline WCRF score and provides a standard nutrition education workshop; participants in the intervention arm also receive training and support to use the Open Food Facts app to identify and avoid ultra-processed foods. Dietary intake and UPF exposure are measured at baseline and after 12 weeks using an adapted food frequency questionnaire and WCRF scoring. The study tracks frequency of app use and analyzes determinants of behavior change to identify who benefits most. Outcomes will compare changes in UPF consumption and overall diet quality between the education-only and app-supported arms.
Who should consider this trial
Good fit: Adults over 18 enrolled in the Interception program who are at increased cancer risk, have a baseline WCRF score ≤ 5, speak French, own a smartphone, and agree to complete study questionnaires.
Not a fit: People who already follow strong cancer-prevention diets (WCRF > 5), cannot use a smartphone, have cognitive or psychiatric conditions, or are under legal guardianship are unlikely to benefit or are excluded.
Why it matters
Potential benefit: If successful, the intervention could help people at high cancer risk improve overall diet quality and potentially lower their future cancer risk by reducing ultra-processed food intake.
How similar studies have performed: Previous digital nutrition and food-labeling app studies have shown modest improvements in food choices, but using Open Food Facts specifically to reduce ultra-processed food intake is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age \> 18 years, 2. Individuals at increased risk of different cancers as defined within the Interception program, 3. With a baseline WCRF score ≤ 5 at entry in the Interception program, 4. Agreeing to participate and who have given their written agreement for the study, 5. Agreeing to fill in the questionnaires on the dedicated platform for the duration of the study, 6. Participant have and accept to use their smartphone, 7. All participants must understand spoken and written French language Exclusion Criteria: 1. Psychiatric disorders or cognitive impairments precluding participation, 2. Patient under guardianship or deprived of his liberty by a judicial or administrative decision or incapable of giving its consent.
Where this trial is running
Avignon and 2 other locations
- Institut Sainte Catherine — Avignon, France (Not_yet_recruiting)
- Eugène Marquis — Rennes, France (Recruiting)
- Gustave Roussy — Villejuif, France (Recruiting)
Study contacts
- Study coordinator: Bruno Raynard, MD
- Email: bruno.raynard@gustaveroussy.fr
- Phone: +33 (0) 1 42 11 42 11
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.