Condition
Mental Health Issue clinical trials and research
As of November 12, 2026, Find a Trial lists 52 Mental Health Issue clinical trials that are recruiting, at sites in 18 countries (most in United States (27), Sweden (3), France (3)). By phase: Phase 2 (1), Phase 3 (1), Phase 4 (1). The most active sponsors are Texas Tech University (3), Copenhagen University Hospital, Rigshospitalet (2), University of Miami (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 52Clinical trials
- 18Countries
Newest Mental Health Issue clinical trials
All recruiting trials (52)
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Virtual Reality Program to Support Healthcare Workers
A brief immersive virtual reality program is being tested to see if it helps reduce burnout and improve well-being for healthcare workers.
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Intensive case management linking VA and community care to prevent suicide in Veterans
This trial will test whether SUPERCEDE, an intensive case-management program that links VA and VA-authorized community care, helps Veterans at risk for suicide get faster, better-coordinated mental health care than present-centered therapy.
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GENESIS: Understanding mental health and lifestyle needs of Ecuadorian adolescents
This project will look at mental health and lifestyle habits in 14–19-year-olds in Quito to see if lifestyle factors relate to well‑being and risk for mental health problems.
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Eco-anxiety and suicide risk in youth in France
This study tests whether climate-related anxiety is linked to suicidal thoughts in young people aged 16–24 in France.
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On-demand and apprenticeship training to help mentors deliver a teen depression-prevention program
This project will test whether on-demand online modules plus supervised, in-the-moment apprenticeship training helps mentors in rural schools deliver IPT-AST to teens aged 12–17.
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Telehealth to improve quality of life for rural Texans
This project will test whether adding two weekly check-in calls to Cognitive Behavioral Therapy helps adults in rural Texas who are family caregivers for someone with dementia improve their mental health and quality of life.
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Gii'Igoshimong — Sitting With Your First Family ceremonial program for Ojibwe/Anishinaabe adults
This project will test whether taking part in the Gii'igoshimong ceremony helps Ojibwe/Anishinaabe adults who used substances in the past 30 days reduce substance use and improve related mental health and protective factors.
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Pasteurised donor human milk for term babies born to mothers with diabetes
This trial will try giving pasteurised donor human milk instead of formula to term infants of mothers with diabetes during the first five days to see if it reduces neonatal unit admissions for low blood sugar.
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Teacher-delivered mental health support for K–8 students in North Carolina
This project tests whether training elementary and middle school teachers in North Carolina to deliver brief mental health support can help K–8 students with depression, anxiety, or behavior problems.
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Virtual registry for menopause and perimenopause in Australia
This study is creating an online registry to collect information from Australian women about their experiences with menopause and perimenopause to help improve healthcare and support for them.
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Virtual screening and intervention for adolescent alcohol use in primary care
This study is testing a new online program to help doctors in pediatric clinics quickly identify and support teenagers who might be struggling with alcohol and drug use.
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Counseling program for Black women living with HIV
This study tests a counseling program for Black women living with HIV to see if it helps them stick to their medication and cope with trauma better than standard care.
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Digital tool to support maternal mental health during pregnancy
This study is testing a new app to see if it can help pregnant women feel better and support their mental health during pregnancy.
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Understanding recovery expectations in acute respiratory failure survivors and their caregivers
This study looks at how adults who survive acute respiratory failure and their caregivers feel about recovery in the first six months after leaving the hospital to see if shared expectations can help improve their mental health.
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Monitoring suicide risk in adolescents using biometric data
This study is testing whether using data from wearable devices can help spot rising suicide risk in teenagers so that they can get help before a crisis happens.
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Psychiatric consultation intervention in primary care settings
This study is testing a new way for primary care doctors in Switzerland to work with mental health experts to see if it helps them better support patients with mental health issues.
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An art exhibition aimed at reducing mental health stigma
This study is testing whether an art exhibition can help reduce stigma around mental health issues for people with mental disorders, their families, and the general public.
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Mobile health outreach for men's cancer screening
This study is testing a mobile health service that brings cancer screening directly to men at their workplaces, especially those in high-risk groups, to help them get checked for prostate cancer and other urological issues.
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Cognitive testing for stress-induced exhaustion and depression
This study is trying to see if different tests can help tell apart stress-induced exhaustion and depression in adults aged 18 to 65, to improve how we diagnose and treat these conditions.
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Impact of Traditional Chinese Medicine on Breast Cancer Patients' Vital Energy
This study is testing whether a Traditional Chinese Medicine program can help breast cancer patients feel better and improve their quality of life while they are receiving regular treatments.
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Improving sleep for better mental health and school performance in teenagers
This study tests two school programs designed to help teenagers aged 13-19 improve their sleep to see if it can boost their mental health and school performance.
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Teacher-led mental health care for adolescents
This study is testing a new way for trained teachers to provide mental health support to teenagers in rural schools to see if it helps them with emotional and behavioral challenges.
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StartHjelp: a digital pre-therapy education program for adults on outpatient mental health waiting lists
This will test whether the StartHjelp digital pre-therapy education program helps adults on outpatient mental health waiting lists feel more prepared, engaged, and satisfied with their care.
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Evaluating a new mental health group for Asians and Asian Americans
This study is testing a 12-week mental health group for Asian and Asian American patients to see if it helps them feel better and more connected to others.
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Exploring the role of gut microbiota in anorexia nervosa
This study looks at how the bacteria in the gut might be linked to anorexia nervosa in women aged 16-50 with a low body weight to see if it can help improve treatment options.
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Peer-based intervention to increase PrEP use among Black sexual minority men
This study is trying to see if a community program can help Black sexual minority men in Prince George's County start and stick with PrEP to prevent HIV by reducing stigma and building support.
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Validation of a mental health model in the Chinese community
This study is trying to see if a mental health model works well for people in the Chinese community and how their experiences might differ from those in Western cultures.
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Improving mental health for home health aides
This study tests if an 8-week program that combines health education and positive thinking can help improve the mental health of home health aides.
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Online emotion-regulation treatment for youth mental health
This study is testing an online program to help teenagers aged 12-17 manage their emotions better and see if it can improve their mental health.
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Improving mental health support in middle schools
This study tests whether different training methods for school staff can help them better support the mental health needs of middle school students.
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Community Connections for treating emotional disorders in youth
This study is testing a new therapy program for kids and teens with anxiety and depression to see if it helps them feel better, and it involves both the youth and their parents.
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Combining brain stimulation and virtual reality for cognitive rehabilitation in older adults with Mild Cognitive Impairment
This study is testing whether combining brain stimulation with virtual reality training can help older adults with Mild Cognitive Impairment improve their thinking skills and mood.
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Coaching to Reduce Work Stress for Health Workers
This study is testing if a special coaching program can help rural health workers in India feel less stressed at work compared to those who only get regular supervision.
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Improving recovery after ACL surgery with virtual therapy
This study is testing if a virtual therapy program can help people recover better and get back to sports after ACL surgery compared to just regular care.
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Investigating the effects of mindfulness meditation on mental health
This study is testing how mindfulness meditation affects mental health and whether personal factors like trauma or negative thinking change the results for people taking part in the program.
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A program to support mental health in American Indian and Alaska Native communities
This study is testing a new program designed to help pregnant women and caregivers in American Indian and Alaska Native communities improve their mental health and coping skills.
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Evaluating online psychological interventions for mental health
This study is testing different online mental health programs to see if they can help people in Hong Kong with moderate to severe anxiety and depression feel better while they wait for traditional therapy.
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Improving preschoolers' mental health through parenting programs
This study tests if a parenting program can help parents support their preschoolers better and reduce behavior problems in kids from families that need extra help.
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Examining mental health issues in endurance athletes
This study looks at how common mental health issues like depression and anxiety are among endurance athletes, such as marathon runners and triathletes, to better understand their experiences.
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Therapy for LGBTQ adults and their nonaccepting parents
This study is testing whether online therapy for LGBTQ adults with nonaccepting parents can help reduce feelings of depression and anxiety.
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Online screening for mental health in children with heart defects
This study is testing an online screening tool to see if it can help identify mental health issues in children with heart defects and provide families with useful information and support.
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Improving mental health in schools through mindfulness and therapy
This study is testing a mindfulness program for teachers and a special therapy for kids in Puerto Rico to see if it helps them feel less stressed and recover from trauma.
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Telehealth support for family caregivers of dementia patients
This study is testing whether online mental health support can help family caregivers of people with dementia feel less stressed and overwhelmed.
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Investigating the risks of anabolic steroid use in fitness communities in Denmark
This study looks at the long-term health risks of using anabolic steroids among recreational athletes in Denmark to see how it affects their heart, diabetes, reproductive health, and mental well-being.
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Telehealth therapy for sexual minority women's mental health and heavy drinking
This study is testing a new online therapy program for sexual minority women to see if it can help reduce heavy drinking and improve mental health compared to standard therapy.
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Improving body image for head and neck cancer survivors
This study is testing a new video therapy program to see if it can help head and neck cancer survivors feel better about their body image and improve their overall well-being.
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Reducing mental health issues in caregivers of dementia patients
This study is testing different therapy options to see if they can help caregivers of dementia patients feel less stressed and overwhelmed.
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Exploring mental health and sexuality in adolescents and young adults
This study is testing how mental health issues and medications affect the sexual health of teens and young adults to improve conversations about this topic in psychiatric care.
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Mitochondrial and stress-related traits linked to preterm birth
This project will test whether mitochondrial DNA and stress-response changes during early pregnancy are linked to the risk of having a preterm birth in pregnant women under 28 weeks.
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Consultation to reduce medication side effects using genetic information
This study is testing if a personalized clinic can help adults taking multiple medications by using their genetic information to reduce side effects and improve how their medicines work.
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Reducing burnout in therapists delivering trauma care for children
This study is testing new ways to help therapists who work with children affected by trauma feel less burned out so they can keep providing effective therapy.
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Observational study on integrative medical care for chronic illnesses and mental health
This study is testing how a team approach to integrative medical care can help adults and children with chronic illnesses and mental health issues feel better.
Related topics
Quick answers
How many Mental Health Issue clinical trials are recruiting right now?
52, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 18 countries. The most sites are in United States (27 trials), Sweden (3 trials), France (3 trials), Denmark (2 trials), Norway (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 1, Phase 3: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.