Mobile health outreach for men's cancer screening
The Man Van Project: An Evaluation of the Effectiveness of a Mobile Outreach Screening Clinic Model for Earlier Detection of Prostate Cancer and Other Male Cancers
This study is testing a mobile health service that brings cancer screening directly to men at their workplaces, especially those in high-risk groups, to help them get checked for prostate cancer and other urological issues.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 4000 (estimated) |
| Ages | 18 Years and up |
| Sex | Male |
| Sponsor | Royal Marsden NHS Foundation Trust Academic / other |
| Locations | 1 site (London) |
| Trial ID | NCT06357416 on ClinicalTrials.gov |
What this trial studies
The Man Van Project is a mobile clinical outreach service designed to provide easy access to cancer screening and healthcare for men, particularly those in manual labor jobs and from black and minority ethnic communities. The initiative focuses on prostate cancer and other urological diseases, addressing barriers to early diagnosis such as low education levels and difficult access to primary care. By collaborating with employers and unions, the project aims to reach high-risk populations directly at their workplaces. The service includes various sub-studies to evaluate different aspects of health screening and intervention.
Who should consider this trial
Good fit: Ideal candidates for this project are men aged 45 and older, particularly those working in manual labor or low-skill jobs.
Not a fit: Patients who are not male or those under the age of 45 may not receive benefit from this project.
Why it matters
Potential benefit: If successful, this project could significantly improve early detection and treatment outcomes for prostate and other cancers in underserved male populations.
How similar studies have performed: Other studies have shown success with mobile health interventions targeting underserved populations, indicating a promising approach for this initiative.
Eligibility criteria
Show full inclusion / exclusion criteria
Patients are eligible to be included in the research study if they are eligible to access the Man Van mobile outreach clinic, which is a novel clinical service delivered by The Royal Marsden Hospital NHS Foundation Trust. The inclusion and exclusion criteria have been designed to be as broad as possible, in order to include data from as many patients using the Man Van clinical service as possible. As the primary purpose of the Man Van mobile outreach clinic is to screen for prostate, testicular, penile and other cancers that affect men, only men are eligible to be reviewed in the mobile outreach clinic hence only males will be recruited into this study. Inclusion criteria for the Main Study 1. Participating in the linked Man Van mobile outreach clinic 2. Age ≥45 years 3. Male (The initial pilot study had a age criteria of ≥18 years, but this was amended). MV-POCT Inclusion Criteria: Any patient having a PSA and/or an HbA1c test as part of a Man Van work up, or via the our rapid diagnostics clinic. MV-QualQ Inclusion Criteria: Any patient attending the Man Van for an assessment. MV-Eco Inclusion Criteria: Any patient attending the Man Van for an assessment. MV-PRS Inclusion Criteria: Any patient attending the Man Van for an assessment and able to provide saliva samples. MV-DNA Inclusion Criteria: Any patient attending the Man Van for an assessment, and able to provide blood/saliva samples. MV MV-UctDNA Inclusion Criteria: Any patient attending the Man Van for an assessment, and able to provide urine samples. MV-SSI Inclusion criteria: * Aged \> 18 and over (on date of invitation to participate) * Works for healthcare organisation, other stakeholder or professional or potential man van patient who was not seen or relative of a Man Van patient/potential patient Exclusion criteria: * Man van patient who has attended appointment MV-TPP Inclusion criteria: Healthcare Professionals * Aged \> 18 and over (on date of invitation to participate) * Speaks English * Works within the UK * Profession: GPs, Practice Staff (Nurses, Physician Assistants and Associates * Healthcare assistants) * Experienced in adopting new tests and guidelines into practice. * Experienced in detecting, managing, and referring symptoms and asymptomatic patients with symptoms of prostate, pancreatic, GI cancer and/or are at an increased risk of developing these cancers. Patients * Aged \> 18 and over (on date of invitation to participate) * Speaks English * Lives in the UK * Patients with direct and in-direct experience with prostate, pancreatic, GI cancers. * Patients at an increased risk of developing prostate, pancreatic, GI cancer in accordance with known risk factors, which includes age, smoking, being overweight or obese, family history and genetic factors, pancreatitis, and diabetes. Other key stakeholders/professionals • Aged \> 18 and over (on date of invitation to participate) • Speak English * Works within the UK * Professions: medical devices and biomedical researchers, scientists, representatives for major regulatory and funding bodies * Knowledgeable of Early Detection initiatives (tests, outreach programes) Exclusion criteria: GPs • Individuals who are unwilling to take part in the study. * Individuals with no experience in adopting new cancer tests and guidelines into practice. * Individuals with no experience in in detecting, managing, and referring patients with symptoms of cancer and/or are at an increased risk of developing prostate, pancreatic, GI cancer. * Individuals who do not adequately understand verbal explanations or written information in English. Patients • Individuals who are unwilling to take part in the study. • Individuals who do not adequately understand verbal explanations or written information in English. • Unable to provide written and verbal consent. • No direct or indirect lived experience with prostate, pancreatic, GI cancers. Non-clinical key stakeholders/professionals • Individuals who are unwilling to take part in the study • Individuals who are not familiar with cancer biomarkers and medical tests • Individuals with no knowledge of early detection • Individuals who do not adequately understand verbal explanations or written information in English
Where this trial is running
London
- Royal Marsden Hospital NHS Foundation Trust — London, United Kingdom (Recruiting)
Study contacts
- Principal investigator: Nicholas D James, MBBS, FRCP, FRCR, PhD — Institute of Cancer Research/Royal Marsden NHS Trust
- Study coordinator: Nicholas D James, MBBS, FRCP, FRCR, PhD
- Email: nick.james@icr.ac.uk
- Phone: 02071535130
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.