Clinical trial Recruiting at 1 site Observational Ages 18 and up

Validation of a mental health model in the Chinese community

Official title: Chinese Community Sample of Hierarchical Model of Psychopathology : Validation and Analysis of Underline Trans-diagnostic Risk Factors

Run by Shanghai Mental Health Center · NCT06105970 · Data updated 2026-11-12

This study is trying to see if a mental health model works well for people in the Chinese community and how their experiences might differ from those in Western cultures.

More Mental Health Issue trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment4000 (estimated)
SponsorShanghai Mental Health Center
Academic / other
Locations1 site (Shanghai)
StatusRecruiting
StartedSeptember 26, 2023
Main results expectedNovember 1, 2024
Study endsNovember 1, 2027
Registry record updatedJuly 10, 2025
Trial IDNCT06105970 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are Chinese citizens aged 18 and older with at least 9 years of education.

Probably not a fit

Patients with severe mental health conditions that impair self-awareness, such as schizophrenia or severe depression, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to validate the Hierarchical Model of Psychopathology (HiTOP) within Chinese community samples, addressing issues of diagnostic heterogeneity and high comorbidity in psychiatric classifications. It will explore cultural differences in the HiTOP model between Western and Eastern cultures, examine the impact of adverse childhood experiences on HiTOP dimensions, and investigate the relationship between unique psychological variables and psychopathological dimensions. Participants will complete detailed surveys measuring their symptoms and experiences, with follow-up assessments over four years to monitor changes.

Why it matters

Potential benefit: If successful, this study could enhance the understanding and treatment of mental health issues in the Chinese population by providing a more accurate diagnostic framework.

How similar studies have gone: While the HiTOP model has been explored in Western contexts, this study represents a novel approach to validating it within the Chinese cultural framework.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Chinese citizens
2. Years of education \> =9 years.
3. age \>= 18 years old.

Exclusion Criteria:

(1)Subjects who have insufficient self-awareness, and are unable to obtain complete informed consent, such as: schizophrenia, manic episode of bipolar disorder, severe depression.

Where it's running

  • Shanghai Mental Health Center
    Shanghai, China
    Recruiting

Study contacts

  • Principal investigator: Zhen Wang, PhD, MD — Shanghai Mental Health Center
  • Study coordinator: Zhen Wang, Phd, MD
  • Email: wangzhen@smhc.org.cn
  • Phone: +8634773516

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.