Clinical trial Recruiting at 2 sites Observational Ages 18 and up

Investigating the effects of mindfulness meditation on mental health

Official title: Who Fares Best With Mindfulness Meditation - Understanding the Individual Effects of Mindfulness

Run by KU Leuven · NCT05862636 · Data updated 2026-11-12

This study is testing how mindfulness meditation affects mental health and whether personal factors like trauma or negative thinking change the results for people taking part in the program.

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Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment120 (estimated)
SponsorKU Leuven
Academic / other
Locations3 sites (Antwerp and 2 other locations)
StatusRecruiting
StartedFebruary 21, 2023
Main results expectedJanuary 2026
Study endsJanuary 2026
Registry record updatedJanuary 6, 2025
Trial IDNCT05862636 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults enrolled in a mindfulness-based intervention who are interested in understanding the effects of mindfulness on their mental health.

Probably not a fit

Patients who do not have access to the internet or lack proficiency in Dutch or English may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore how individual differences affect the outcomes of mindfulness meditation, particularly focusing on its benefits and potential harms. Participants enrolled in a Mindfulness-Based Intervention will complete self-report questionnaires at various stages of the program to assess symptoms of anxiety and depression, quality of life, and wellbeing. The study will also investigate the mechanisms through which mindfulness meditation may influence mental health, as well as how factors like trauma symptoms, dissociation, and negative thinking may impact these effects.

Why it matters

Potential benefit: If successful, this study could help identify which individuals benefit from mindfulness meditation and which may experience adverse effects, leading to more personalized mental health interventions.

How similar studies have gone: Other studies have shown varying effects of mindfulness meditation, but this specific focus on individual differences and potential harms is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Enrolled in a mindfulness-based intervention at one of the participating sites

Exclusion Criteria:

* Insufficient knowledge of the Dutch or English language (depending on the study site)
* No internet access

Where it's running

  • ZNA Stresskliniek
    Antwerp, Belgium
    Recruiting
  • Mindful Me
    Deinze, Belgium
    Recruiting
  • AccEPT clinic
    Exeter, United Kingdom
    Withdrawn

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.