Investigating the effects of mindfulness meditation on mental health

Who Fares Best With Mindfulness Meditation - Understanding the Individual Effects of Mindfulness

Observational KU Leuven · NCT05862636

This study is testing how mindfulness meditation affects mental health and whether personal factors like trauma or negative thinking change the results for people taking part in the program.

Quick facts

Study typeObservational
Enrollment120 (estimated)
Ages18 Years and up
SexAll
SponsorKU Leuven Academic / other
Locations3 sites (Antwerp and 2 other locations)
Trial IDNCT05862636 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore how individual differences affect the outcomes of mindfulness meditation, particularly focusing on its benefits and potential harms. Participants enrolled in a Mindfulness-Based Intervention will complete self-report questionnaires at various stages of the program to assess symptoms of anxiety and depression, quality of life, and wellbeing. The study will also investigate the mechanisms through which mindfulness meditation may influence mental health, as well as how factors like trauma symptoms, dissociation, and negative thinking may impact these effects.

Who should consider this trial

Good fit: Ideal candidates for this study are adults enrolled in a mindfulness-based intervention who are interested in understanding the effects of mindfulness on their mental health.

Not a fit: Patients who do not have access to the internet or lack proficiency in Dutch or English may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help identify which individuals benefit from mindfulness meditation and which may experience adverse effects, leading to more personalized mental health interventions.

How similar studies have performed: Other studies have shown varying effects of mindfulness meditation, but this specific focus on individual differences and potential harms is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Enrolled in a mindfulness-based intervention at one of the participating sites

Exclusion Criteria:

* Insufficient knowledge of the Dutch or English language (depending on the study site)
* No internet access

Where this trial is running

Antwerp and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HealthyDepressionMental Health Issue
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.