Condition

Grief clinical trials and research

• 10Clinical trials
• 16NIH research projects
• 1Country

Newest Grief clinical trials

All recruiting trials (10)

• Self-affirmation and heart responses during grief

  This trial will test whether a brief self-affirmation exercise helps adults grieving a recent loss have calmer heart and blood pressure responses during and after recalling their loss.

  Recruiting University of South Florida · Tampa, Florida · NCT07356635

• ACT for people with MNCD and their care partners (dyadic therapy)

  This study tests a dyadic Acceptance Commitment Therapy approach to help adults with mild neurocognitive disorder or mild cognitive impairment and their care partners.

  Recruiting Phase 1 Texas Tech University · Lubbock, Texas · NCT07239609

• Walk With Me for Perinatal Grief

  A mobile app-based program (Along With Me) with or without a Peer Guide is tested to see if it lowers posttraumatic stress and suicidal thoughts in bereaved parents after pregnancy or early infant loss.

  Recruiting Oregon Research Behavioral Intervention Strategies, Inc. · Eugene, Oregon and 1 other locations · NCT07011940

• Training behavioral health technicians to improve mental health support for military personnel

  This study is testing whether giving special training to behavioral health technicians can help active-duty airmen feel better and manage stress more effectively compared to those who get care from untrained technicians.

  Recruiting New York University · New York, New York · NCT06981598

• Support for families grieving an overdose loss

  This project will test a peer-led grief support program called RIVER to help adults who lost a loved one to an unintentional drug overdose within the past year.

  Recruiting at 3 sites Rand · Birmingham, Alabama and 3 other locations · NCT06854757

• Nature-based guided meditation to support people grieving a loved one with cancer

  This program will try short, easy nature-based guided meditations to help adults who lost a family member or friend to cancer cope with grief during the first six months after the death.

  Recruiting Michigan State University · East Lansing, Michigan · NCT06662409

• Telehealth support for family caregivers of dementia patients

  This study is testing whether online mental health support can help family caregivers of people with dementia feel less stressed and overwhelmed.

  Recruiting Texas Tech University · Lubbock, Texas · NCT05696704

• Accelerated Resolution Therapy for Grief in Family Caregivers

  This study is testing if a new therapy called Accelerated Resolution Therapy can help older family caregivers deal with grief before a loss and improve their emotional well-being.

  Recruiting at 4 sites Mayo Clinic · Phoenix, Arizona and 3 other locations · NCT05624879

• Reducing mental health issues in caregivers of dementia patients

  This study is testing different therapy options to see if they can help caregivers of dementia patients feel less stressed and overwhelmed.

  Recruiting Texas Tech University · Lubbock, Texas · NCT05334992

• Comparing grief therapy approaches for parents who lost a child

  This study tests which of three different support programs can help parents cope better with the grief of losing a child to cancer.

  Recruiting at 4 sites University of Miami · Stanford, California and 4 other locations · NCT05142605

NIH-funded research (16)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Helping families coping with overdose bereavement and substance use support

  A patient-friendly program tests a peer grief support approach to help people who lost loved ones to overdose and may also help reduce risky substance use.

  NIH research Stanford University · Stanford, United States · NIH-11454648

• Walk with Me for Perinatal Grief: an online support and training tool for families and clinicians

  A digital program called Walk with Me for perinatal grief helps families who have lost a baby and the healthcare team to cope with grief and trauma.

  NIH research Oregon Res Behavioral Intervention Strat · Springfield, UNITED STATES · NIH-11379151

• Long-lasting grief after losing a loved one in older adults

  Researchers are finding how common long-lasting grief is and what factors make it more or less likely for adults aged 65 and older.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11303447

• Accelerated Resolution Therapy for grief in older caregivers

  A clinical trial tests a brief therapy called Accelerated Resolution Therapy to help older family caregivers cope with maladaptive grief after losing loved ones.

  NIH research Mayo Clinic Jacksonville · Jacksonville, United States · NIH-11298955

• Support for Parents After Pregnancy or Infant Loss

  This project creates a web-based tool to help parents cope with the emotional challenges and grief after losing a pregnancy or infant.

  NIH research Oregon Res Behavioral Intervention Strat · Springfield, UNITED STATES · NIH-11196769

• Understanding prolonged grief disorder in older adults after losing a loved one

  This study is looking at how common prolonged grief disorder is among older adults who have lost someone they love, and it aims to find out what helps some people cope better than others, so we can improve support and treatment for those who are struggling.

  NIH research Harvard School of Public Health · Boston, United States · NIH-11137732

• Finding Meaning After Losing a Child to Cancer

  This project offers a special type of grief support called Meaning-Centered Grief Therapy to parents who have lost a child to cancer, helping them cope with their profound loss.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11119027

• A therapy to help older adults cope with grief

  This study is looking at how a special therapy called Accelerated Resolution Therapy (ART) can help older family caregivers who are struggling with grief before they lose a loved one, to see if it can make them feel better and prevent long-lasting sadness.

  NIH research Mayo Clinic Jacksonville · Jacksonville, United States · NIH-11109437

• Helping families cope with grief and substance use after drug overdose deaths

  This study is looking at how to help families who have lost someone to a drug overdose by offering them support from others who understand their pain, using a program called the RIVER model, to help them cope with their feelings and connect with helpful resources.

  NIH research Stanford University · Stanford, United States · NIH-11059008

• Improving how we measure grief after limb amputation to enhance health outcomes.

  This study is looking at how people feel emotionally after losing a limb and aims to create better ways to understand and support those feelings, so that healthcare providers can help patients heal both physically and emotionally.

  NIH research University of Washington · Seattle, United States · NIH-11032395

• A program to support parents dealing with pregnancy and infant loss

  This study is testing a helpful online program called Along With Me, designed for parents who have gone through the heartbreak of losing a pregnancy or infant, to provide them with support and tools to cope better with their grief.

  NIH research Oregon Res Behavioral Intervention Strat · Springfield, UNITED STATES · NIH-11003949

• Understanding grief in Latinx families who have lost a child to cancer

  This study looks at how social issues impact the grief of Latinx families in the U.S. who have lost a child to cancer, aiming to understand their unique challenges and find ways to better support them during this tough time.

  NIH research Duke University · Durham, United States · NIH-10992827

• An educational game to teach high schoolers about the gut microbiome

  This study is creating a fun online game for high school students to help them learn about the gut microbiome and how it affects health, while also sparking their interest in science and public health.

  NIH research Smart Information Flow Technologies · Minneapolis, United States · NIH-10922093

• The impact of grief on health in survivors of the World Trade Center attacks

  This study is looking at how the grief and trauma from the 9/11 attacks affect the health and well-being of survivors who lost loved ones, and it aims to understand their needs better to help improve support for them.

  NIH research Henry M. Jackson Fdn for the Adv Mil/med · Bethesda, United States · NIH-10869853

• Helping caregivers and patients with Alzheimer's share memories and improve relationships

  This study is looking at how sharing memories through fun activities can help people with Alzheimer's and their caregivers feel closer and happier, while also making it easier for caregivers to handle tough decisions.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-10836503

• Understanding how brain function affects grief in older adults

  This study is looking at how the brain helps older adults manage their feelings after losing someone they love, to see if it can help predict who will heal from their grief and who might need more support.

  NIH research Medical College of Wisconsin · Milwaukee, United States · NIH-10764217

Related topics

Quick answers

How many Grief clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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