Translate and validate the MQOL quality-of-life questionnaire into French for people with meningioma
Translation and Validation of the MQOL Self-questionnaire Into French for Assessing Quality of Life in Patients With Meningiomas
This project will translate the MQOL quality-of-life questionnaire into French and try it with adults who have intracranial meningioma to see if it works well in French.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier St Anne Academic / other |
| Locations | 1 site (Paris) |
| Trial ID | NCT07044076 on ClinicalTrials.gov |
What this trial studies
This observational project will produce a French translation of the MQOL self-questionnaire and perform linguistic validation. In a second phase, the translated MQOL will be tested in 50 adults with confirmed intracranial meningioma and compared with EQ-5D, Karnofsky Performance Status, and FACT-Br to examine reliability and internal consistency. Eligible participants are French-speaking adults able to give informed consent; pregnant, legally restricted, or psychiatric inpatients are excluded. The work will be conducted at GHU Paris - Psychiatrie & Neurosciences (Centre Hospitalier Sainte-Anne) in Paris.
Who should consider this trial
Good fit: Adults (18+) with an intracranial meningioma confirmed by imaging or surgery who are fluent in French and able to provide informed consent are the intended participants.
Not a fit: People who are not fluent in French, are pregnant or breastfeeding, are deprived of liberty or under psychiatric detention, or cannot give informed consent are not eligible and are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, clinicians and researchers will have a validated French MQOL that can more accurately measure quality of life and guide care for French-speaking meningioma patients.
How similar studies have performed: The MQOL instrument has been translated and validated in other languages and settings, so this translation-and-validation approach follows an established and previously successful methodology.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient aged 18 years or older * Diagnosis of intracranial meningioma confirmed by imaging or surgery Exclusion Criteria: * Pregnant or breastfeeding women (Article L1121-5) * Patients deprived of liberty by judicial or administrative decision, as well as individuals undergoing psychiatric care (Article L1121-6) * Patients not fluent in French or with poor understanding of the language * Inability to refuse participation in the study
Where this trial is running
Paris
- GHU Paris -Psychiatrie & Neurosciences — Paris, France (Recruiting)
Study contacts
- Study coordinator: Viviane AWASSI
- Email: v.awassi@ghu-paris.fr
- Phone: 01.45.65.84.86
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.