Assessing cognitive outcomes after skull base meningioma surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the long-term cognitive outcomes of patients who undergo surgery for the removal of skull base meningiomas located in the frontal or temporal lobes. Participants will be assessed for cognitive function at baseline, six weeks post-surgery, and one year post-surgery using a series of standardized cognitive tests administered by a speech language pathology team. The study will utilize assessments such as the RBANS tests, MoCA, PROMIS-29, and NeuroQOL-Cognitive Functions to measure changes in cognitive status over time.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subject has a meningioma associated with the frontal or temporal lobes
* Subject is scheduled to undergo open craniotomy or Endoscopic Endonasal surgery
* Subject is 18 years of age or older
* The subject must in the investigator's opinion, be psychosocially, mentally, and physically able to fully comply with this protocol including the required follow-up visits, the filling out of required forms, and have the ability to understand and give written informed consent
* Previous surgery will not exclude the patient as a new baseline cognitive evaluation will occur.

Exclusion Criteria:

* Patient is a prisoner
* Patient is 90 years of age or older
* Pregnant women
* Previous radiation to the brain

Where it's running

• Ohio State University Wexner Medical Center
  Columbus, Ohio, United States Recruiting

Study contacts

• Principal investigator: Daniel Prevedello, MD — Ohio State University
• Study coordinator: Emma Kurtz, BS
• Email: Emma.Kurtz@osumc.edu
• Phone: (614) 685-4534

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.