Evaluating meningioma properties using 3D magnetic resonance elastography

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective study aims to assess the feasibility and clinical utility of three-dimensional magnetic resonance elastography (3D MRE) in evaluating the stiffness and adhesion of meningiomas in patients undergoing surgical resection. By correlating preoperative MRE-derived stiffness and adhesion maps with intraoperative findings and histopathological features, the study seeks to establish MRE as a noninvasive imaging biomarker for surgical planning and risk stratification. Approximately 300 patients with confirmed meningioma will undergo standard MRI and additional 3D MRE scanning, with intraoperative findings systematically recorded for analysis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All patients undergoing meningeoma resection surgery are eligible for inclusion in the study cohort.

Exclusion Criteria:

* Patients with metallic implants or foreign bodies in their bodies (pacemakers, artificial metallic heart valves, metal joints, metal implants, and those who can not remove dentures, insulin pumps, or contraceptive rings)
* Pregnant women in the first trimester (within three months)
* Patients with severe claustrophobia or anxiety
* Patients with severe fever
* Patients who can not tolerate MRE
* Patients with vascular malformations and aneurysms.
* Patients who do not sign an informed consent

Where it's running

• Shengjing Hospital
  Shenyang, Liaoning, China Recruiting

Study contacts

• Principal investigator: Yu Shi, MD — Shengjing Hospital
• Study coordinator: Yu Shi, MD
• Email: 18940259980@163.com
• Phone: +86 189 4025 9980

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.