Effects of Salovum® and SPC® Flakes on Brain Tumor Edema

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the impact of Salovum®, an egg yolk powder rich in antisecretory factor, and SPC® flakes, processed oats, on cerebral edema caused by brain tumors. Participants will consume these products over a 28-day period while their neurological and cognitive symptoms, as well as MRI changes in edema, will be monitored. The study aims to determine if these interventions can reduce both clinical symptoms and radiological evidence of edema in patients with glioblastoma, cerebral metastases, or meningiomas. The trial also explores the effects in patients who are either steroid refractory or naïve.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 18-79 years
2. Known or radiologically suspected primary or secondary brain tumor (suspected metastasis, meningioma, glioma, etc.) with surrounding edema causing clinical signs
3. GCS 14-15
4. WHO ECOG performance status 0-2
5. Planned or started cortisone treatment
6. Ability to provide informed consent

Exclusion Criteria:

1. Egg yolk allergy
2. Midline shift \>5mm
3. GCS ≤13
4. Epilepsy as sole symptom from the cerebral edema

Where it's running

• Department of Neurosurgery
  Lund, Sweden Recruiting

Study contacts

• Study coordinator: Peter Siesjö, MD, PhD
• Email: peter.siesjo@med.lu.se
• Phone: +46705655778

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.