Condition

Hip Fracture clinical trials and research

• 14Clinical trials
• 14NIH research projects
• 9Countries

Newest Hip Fracture clinical trials

All recruiting trials (14)

• Total Intravenous Versus Inhalational Anesthesia in Hip Fracture Surgery

  This study compares TIVA with sevoflurane anesthesia in people 65 and older undergoing hip fracture surgery to see which method helps them recover better after surgery.

  Recruiting Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital · Istanbul, Istanbul · NCT07860996

• Comparison of meta-PENG vs suprainguinal fascia iliaca block for hip fracture pain

  This study tests whether two ultrasound-guided nerve blocks help with pain control for adults having hip fracture surgery under spinal anesthesia.

  Recruiting Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital · Istanbul, Istanbul · NCT07612761

• Frailty plus Nottingham Hip Fracture Score to predict 90-day death risk after hip surgery

  This project will test whether adding a quick frailty check (Clinical Frailty Scale) to the Nottingham Hip Fracture Score helps doctors better predict 90-day death risk for people aged 60 and older having hip fracture surgery.

  Recruiting Trakya University · Edirne · NCT07481188

• MDW blood test to predict complications and survival after hip fracture

  This will test whether a routine blood measure called Monocyte Distribution Width (MDW) can help predict complications or death in people aged 65 and older who have a low-energy hip fracture.

  Recruiting National and Kapodistrian University of Athens · Kifissia, Attica · NCT07350785

• Comparing regional (spinal) versus general anesthesia effects on breathing after hip fracture surgery

  This study will test whether spinal (regional) or general anesthesia leads to better oxygen levels in people over 65 having hip fracture surgery.

  Recruiting University of Lisbon · Lisbon, Lisbon District · NCT07309575

• Delirium Zero protocol to prevent delirium after hip fracture surgery

  This trial will try whether a family-led Delirium Zero protocol (orientation poster, wall clock, and a caregiver checklist) can prevent delirium in people over 65 having hip fracture surgery.

  Recruiting Cardenal Herrera University · Manises, Valencia and 1 other locations · NCT07202208

• Remote ischaemic conditioning to reduce post-surgical complications after hip fracture

  This tests whether brief cycles of blood-pressure-cuff inflation on an arm or leg can help people with recent hip fractures have fewer complications after their surgery.

  Recruiting Sheffield Teaching Hospitals NHS Foundation Trust · Sheffield, South Yorkshire · NCT07178041

• Remimazolam versus Midazolam for sedation and early thinking recovery in older adults having orthopedic surgery

  This will test whether remimazolam or midazolam gives better sedation and faster early recovery of thinking and memory for people 65 and older undergoing orthopedic surgery with regional anesthesia.

  Recruiting Phase 3 Romanian Society for Enteral and Parenteral Nutrition · Bucharest · NCT07113483

• PENG block: continuous infusion versus programmed intermittent bolus for hip fracture pain

  This will see if giving levobupivacaine through a PENG block as a continuous infusion or as timed intermittent boluses provides better pain relief for adults after neck of femur (hip) fracture surgery.

  Recruiting University College Cork · Cork, Cork · NCT07046052

• How Bleeding Affects Delirium in Older Adults After Hip Fracture

  This trial tests whether early detection of bleeding and prompt blood transfusions can lower delirium risk in people 75 and older with hip fractures.

  Recruiting University of Aarhus · Aarhus, Central Jutland and 1 other locations · NCT06938789

• Intravenous iron to help people regain mobility after hip fracture surgery

  This trial will test whether a single infusion of intravenous iron given soon after hip fracture surgery helps people aged 65 and older regain their walking ability.

  Recruiting at 2 sites Phase 4 University Hospital Bispebjerg and Frederiksberg · Copenhagen NV and 2 other locations · NCT06898814

• Evaluating the CALLY Index for Predicting Delirium After Hip Surgery in Older Patients

  This study is testing if a new index can help predict delirium in older patients after they have hip surgery.

  Recruiting Ankara Ataturk Sanatorium Training and Research Hospital · Ankara, Keçiören · NCT06818409

• Investigating the link between frailty and inflammation in hip fracture patients

  This study is looking to see if older adults with hip fractures who are more frail have higher levels of inflammation in their bodies.

  Recruiting at 2 sites University of Thessaly · Larissa, Thessaly and 1 other locations · NCT06614478

• Comparing intravenous and oral acetaminophen for pain management after hip fracture surgery in older adults

  This study is testing whether giving older adults IV acetaminophen or oral acetaminophen after hip fracture surgery helps them manage pain better and recover more effectively.

  Recruiting Phase 4 University Health Network, Toronto · Toronto, Ontario · NCT05425355

NIH-funded research (14)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• MAC-STILA: Safer, gentler anesthesia for hip fracture in older adults

  A multi-center trial tests a new anesthesia approach (MAC-STILA) to reduce delirium and other problems after hip-fracture surgery in older adults with dementia.

  NIH research New York University School of Medicine · New York, United States · NIH-11399101

• HIP ATTACK-2: Faster surgery for hip fracture patients with heart injury

  A multicenter trial tests whether operating within 6 hours after hip fracture improves survival and recovery for patients who also have acute heart injury.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11382759

• Hip fracture risk in people with chronic kidney disease

  A study focused on why hip fractures happen and how to prevent them in people with chronic kidney disease.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11298380

• How bones weaken in different ways that lead to hip fractures

  This project looks at how differences in bone size, mineral content, and bone area relate to hip fracture risk in older men and women.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11266228

• Monitored sedation with local anesthetic injections for older adults with hip fracture

  This project compares monitored sedation plus local anesthesia injections to standard general anesthesia for older adults having hip fracture surgery to reduce postoperative delirium.

  NIH research New York University School of Medicine · New York, United States · NIH-11226705

• Developing a new treatment to improve muscle recovery after hip fractures in older adults

  This study is testing a new pill called RT-002 to see if it can help older adults heal better and regain strength after a hip fracture, with the hope of making their recovery easier and improving their overall quality of life.

  NIH research Ridgeline Therapeutics, LLC · Houston, UNITED STATES · NIH-11080486

• Understanding how different factors contribute to bone strength decline and hip fractures in older adults

  This study is looking at how bone strength changes as we age and what factors might help predict the risk of hip fractures in older adults, so we can better understand and prevent these injuries.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11074130

• Creating a system to help doctors use regional anesthesia for hip fracture pain without opioids

  This study is working on a new ultrasound tool to help doctors give better pain relief to patients with hip fractures, making it easier for them to find the right spots to inject anesthesia and reducing the need for strong pain medications.

  NIH research Rivanna Medical, INC. · Charlottesville, United States · NIH-10927446

• Rapid hip fracture surgery for patients with recent heart injury

  This project compares having hip fracture surgery within six hours versus usual timing for people whose blood tests show an acute heart injury.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-10897209

• Improving quality of life for older adults recovering from hip fractures

  This study is all about helping older adults who have had hip fractures feel better and recover more easily in their neighborhoods by improving local services and support, especially for those in less advantaged areas.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-10893991

• Understanding hip fractures in patients with chronic kidney disease

  This study is looking at the special challenges faced by people with chronic kidney disease who have hip fractures, to better understand their bone health and help doctors find the best treatments for them.

  NIH research University of California, San Diego · La Jolla, United States · NIH-10768615

• Developing a new treatment to improve muscle strength in older adults after hip fractures

  This study is testing a new treatment that helps older adults, especially those who have had hip fractures, regain muscle strength and improve their recovery after surgery by boosting their muscle repair cells.

  NIH research Ridgeline Therapeutics, LLC · Houston, UNITED STATES · NIH-10696182

• Improving outcomes for hip fracture patients with heart injury through faster surgery

  The HIP ATTACK-2 trial is looking to help people with hip fractures and heart issues by comparing faster surgery within six hours of getting to the hospital to regular surgery, to see if getting treated quicker can help them recover better and live a healthier life.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-10673739

• Assessing hip fracture risk in patients with HIV and HCV

  This study is looking at how having both HIV and hepatitis C affects bone strength and the risk of hip fractures, using special MRI scans to find out more about bone health in these patients compared to those with just hepatitis C and healthy people, all to help improve care for those at risk.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-10666414

Related topics

Quick answers

How many Hip Fracture clinical trials are recruiting right now?

14, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in Turkey (Türkiye) (4 trials), Greece (2 trials), Denmark (2 trials), Ireland (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →