Condition

Regional Anesthesia clinical trials and research

• 15Clinical trials
• 7NIH research projects
• 7Countries

Newest Regional Anesthesia clinical trials

All recruiting trials (15)

• Lateral Quadratus Lumborum Block vs Intrathecal Morphine for Cesarean Section analgesia

  This study tests whether a lateral quadratus lumborum block can provide pain relief after cesarean delivery as effectively as intrathecal morphine.

  Recruiting Ondokuz Mayıs University · Samsun · NCT07712783

• Impact of Communication Delays on Anesthesia Response in Medical Emergencies and Ultrasound-Guided Nerve Blocks

  This study tests how an 80-second communication delay affects the speed and quality of regional anesthesia nerve blocks during emergencies in a spaceflight-like setting.

  Recruiting Nova Scotia Health Authority · Halifax, Nova Scotia · NCT07675863

• ESPB for persistent back pain in ankylosing spondylitis

  This trial tests whether an erector spinae plane block can help reduce persistent back pain in adults with ankylosing spondylitis who still have pain despite controlled disease activity.

  Recruiting Marmara University · Istanbul, Pendik · NCT07633730

• Comparison of meta-PENG vs suprainguinal fascia iliaca block for hip fracture pain

  This study tests whether two ultrasound-guided nerve blocks help with pain control for adults having hip fracture surgery under spinal anesthesia.

  Recruiting Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital · Istanbul, Istanbul · NCT07612761

• Erector spinae plane block versus thoracoscopic intercostal nerve block for pain after VATS lung surgery

  This compares two nerve-block techniques to see which gives better pain control after elective VATS lung surgery in adults.

  Recruiting Sana Klinikum Offenbach · Offenbach, Hesse · NCT07535697

• DIPB vs SIFIB for pain control after total hip replacement

  This will test whether the Deep Iliacus Plane Block (DIPB) or the Suprainguinal Fascia Iliaca Block (SIFIB) gives better pain relief and less leg weakness for adults having elective total hip replacement.

  Recruiting Sivas Numune Hospital · Sivas, Sivas and 1 other locations · NCT07452120

• Sensory mapping of two nerve blocks for laparoscopic gallbladder surgery

  We will test whether two regional nerve blocks (External Oblique Plane and Serratus Intercostal Plane) produce different skin numbness patterns in adults having elective laparoscopic gallbladder removal.

  Recruiting Samsun University · Samsun, Ilkadım · NCT07445854

• Neurological and systemic risks after locoregional anesthesia

  This study tests how often nerve injuries, pneumothorax, and other complications occur after a single-shot regional nerve or fascial plane block in adults.

  Recruiting Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva · Bergamo, Bergamo and 3 other locations · NCT07238933

• Lateral, Anterior, Medial (LAM) femoral cutaneous block for thigh donor-site pain

  This tries to see if a LAM nerve block can numb the anterolateral thigh and reduce donor-site pain without weakening leg muscles in adults having split-thickness skin grafts.

  Recruiting University of Washington · Seattle, Washington · NCT07221903

• Deep brain stimulator battery replacement for people with Parkinson's disease

  This trial tests whether having a DBS battery replacement under regional chest-wall nerve blocks works as well and is as safe as having it under general anesthesia for people with Parkinson's disease aged 40–85.

  Recruiting Ankara Etlik City Hospital · Ankara, Yenimahalle\Ankara · NCT07176494

• Regional anesthesia for knee replacement: effects on early joint motion and patient satisfaction

  We will test whether three different regional anesthesia approaches — an epidural catheter, an adductor canal catheter, or multimodal IV pain control — help adults having elective knee replacement move their knee better and feel more satisfied after surgery.

  Recruiting Konya City Hospital · Konya, Meram · NCT07124494

• Lidocaine versus lidocaine plus dexmedetomidine for IV regional anesthesia in upper limb surgery

  This trial will test whether adding dexmedetomidine to lidocaine for intravenous regional anesthesia gives better pain relief and longer-lasting analgesia for adults having elective upper limb surgery under 45 minutes.

  Recruiting Phase 4 Fatima Memorial Hospital · Lahore, Punjab Province · NCT07034300

• Sacral ESP plus adductor canal block versus iPACK plus adductor canal block for pain control after knee replacement

  This will test whether adding a sacral erector spinae plane (ESP) block to an adductor canal block gives adults having a unilateral knee replacement as good or better pain relief and recovery as adding an iPACK block.

  Recruiting San Giovanni di Dio Hospital · Crotone · NCT07017400

• Using video goggles to reduce stress in patients undergoing vascular surgery

  This study is testing if video goggles can help reduce stress and make patients more comfortable during carotid surgery.

  Recruiting University Hospital Augsburg · Augsburg, Bavaria · NCT06704230

• Database for Ultrasound-guided Peripheral Nerve Blocks

  This study is creating a database to see how well ultrasound-guided nerve blocks work for anesthesia and to track any complications, helping doctors improve their skills and patient care.

  Recruiting Nordsjaellands Hospital · Hillerød · NCT06460792

NIH-funded research (7)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Neural signals in surgical wound healing and how regional anesthesia changes them

  Researchers are studying how nerve signals and the immune system interact after surgery and how regional anesthesia might improve healing.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11377380

• Active monitoring to guide pain and nerve block care during surgery and recovery

  A new method using brain-wave signals could help doctors tailor pain relief during surgery and after, improving comfort and reducing opioid use.

  NIH research Pascall Systems, Incorporated · Boston, UNITED STATES · NIH-11314661

• A device to detect hidden pain signals during and after surgery

  This project uses a scalp sensor to find pain-related brain signals so anesthesiologists can better manage pain during and after surgery.

  NIH research Pascall Systems, Incorporated · Boston, UNITED STATES · NIH-11176849

• Understanding how nerves and immune cells work together to heal surgical wounds

  This research explores how our nerves and immune system talk to each other to heal surgical wounds, and how certain types of pain relief might improve this process.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11162347

• Creating new technologies to better manage pain during and after surgery

  This study is testing new ways to help doctors better manage pain during and after surgery, especially for patients getting regional anesthesia, so they can provide more personalized care and help prevent long-term pain and reliance on pain medications.

  NIH research Pascall Systems, Incorporated · Boston, UNITED STATES · NIH-11160369

• Creating a system to help doctors use regional anesthesia for hip fracture pain without opioids

  This study is working on a new ultrasound tool to help doctors give better pain relief to patients with hip fractures, making it easier for them to find the right spots to inject anesthesia and reducing the need for strong pain medications.

  NIH research Rivanna Medical, INC. · Charlottesville, United States · NIH-10927446

• How nerve signaling affects healing after surgery

  This study is looking at how certain nerve cells and the immune system work together to help surgical wounds heal better, and it's for anyone interested in improving recovery after surgery.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10894113

Related topics

Quick answers

How many Regional Anesthesia clinical trials are recruiting right now?

15, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in Turkey (Türkiye) (7 trials), Italy (2 trials), Germany (2 trials), United States (1 trial), Denmark (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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