Condition

Delirium - Postoperative clinical trials and research

• 23Clinical trials
• 2New in 30 days
• 9Countries

Newest Delirium - Postoperative clinical trials

All recruiting trials (23)

• Impact of Fast-Track Anesthesia on Postoperative Delirium After Cardiac Surgery

  This observational study tests whether fast-track anesthesia, compared with conventional care, is linked to lower rates of delirium after elective cardiac surgery in adults.

  Recruiting Second Affiliated Hospital of Nanchang University · Nanchang, Jiangxi · NCT07923344

• Remimazolam vs. Propofol for Sedation After Cardiac Surgery in Older Adults

  This trial tests whether remimazolam tosylate can lower the rate of postoperative delirium compared with propofol in patients 65 and older after cardiac surgery with bypass.

  Recruiting Nanjing First Hospital, Nanjing Medical University · Nanjing, Jiangsu · NCT07908121

• Dexmedetomidine to See if Delirium Drops After Hip Fracture Surgery

  This observational study tests whether using dexmedetomidine around hip fracture surgery helps prevent postoperative delirium in adults 65 and older.

  Recruiting Aarhus University Hospital · Aarhus · NCT07867899

• How different pain control methods affect early mobilization after major surgery in older ICU patients

  In this real-world study, researchers will observe how pain-relief methods used after major surgery in adults 65 and older in the ICU relate to how quickly they get out of bed and start moving.

  Recruiting Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization · Istanbul, Istanbul · NCT07709975

• VR-based cognitive games to help prevent delirium after big surgery

  A VR-based cognitive stimulation game is being tested to see if it can help prevent delirium in adults 65 and older after major surgery.

  Recruiting at 2 sites The Methodist Hospital Research Institute · Houston, Texas and 1 other locations · NCT07641153

• Sleep problems before heart surgery may affect recovery outcomes

  This study tests whether preoperative sleep issues in adults undergoing cardiac surgery are linked to different perioperative metabolites and postoperative outcomes.

  Recruiting Chinese Academy of Medical Sciences, Fuwai Hospital · Beijing, Beijing Municipality · NCT07588178

• How older adults' brains use extra oxygen during surgery and whether that links to postoperative delirium

  This project tries to see if reduced brain oxygen use during elective laparoscopic surgery under general anesthesia increases the chance of postoperative delirium in people aged 65 and older.

  Recruiting Seoul National University Bundang Hospital · Seongnam-si, Gyeonggi-do · NCT07463586

• Early post-op blood biomarkers and the risk of delirium after major surgery

  We will test whether blood levels of S100B, NSE, IL-6, and Copeptin measured within two hours after surgery can help predict delirium in people 65 and older having major non-cardiac, non-intracranial, non-vascular elective surgery.

  Recruiting Medical University of Vienna · Vienna · NCT07411612

• Personalized iPad audio messages to reduce confusion after hip fracture surgery

  This trial will try 2-minute personalized audio reorientation messages on an iPad to see if they help prevent confusion (delirium) in people aged 60 and over after hip fracture surgery.

  Recruiting Sengkang General Hospital · Singapore · NCT07396532

• Personalized iPad audio messages to reduce confusion after hip fracture surgery

  This trial will try 2-minute personalized audio reorientation messages on an iPad to see if they help prevent confusion (delirium) in people aged 60 and over after hip fracture surgery.

  Recruiting Sengkang General Hospital · Singapore · NCT07396532

• Perioperative EEG variability and risk of postoperative delirium

  This study will see if patterns in EEG recordings before and during surgery can identify older patients at risk for postoperative delirium.

  Recruiting Hainan Medical College · Haikou · NCT07323940

• Delirium Zero protocol to prevent delirium after hip fracture surgery

  This trial will try whether a family-led Delirium Zero protocol (orientation poster, wall clock, and a caregiver checklist) can prevent delirium in people over 65 having hip fracture surgery.

  Recruiting Cardenal Herrera University · Manises, Valencia and 1 other locations · NCT07202208

• How Bleeding Affects Delirium in Older Adults After Hip Fracture

  This trial tests whether early detection of bleeding and prompt blood transfusions can lower delirium risk in people 75 and older with hip fractures.

  Recruiting University of Aarhus · Aarhus, Central Jutland and 1 other locations · NCT06938789

• Using EEG to predict postoperative delirium in neurosurgery patients

  This study is testing if monitoring brain activity with EEG can help doctors predict if adults will experience confusion after having brain surgery.

  Recruiting at 2 sites Beijing Sanbo Brain Hospital · Beijing, Beijing Municipality and 1 other locations · NCT06894238

• Pre-surgery sleep program to reduce delirium after congenital heart surgery in infants and toddlers

  This study will try a short cognitive-behavioral sleep program before elective congenital heart surgery to see if it lowers postoperative delirium in infants and toddlers (0–36 months) with sleep problems.

  Recruiting Chinese Academy of Medical Sciences, Fuwai Hospital · Beijing · NCT06879431

• Improving sleep before heart surgery to reduce delirium in young children

  This study is testing if a special bedtime routine can help young children sleep better before heart surgery and reduce the chances of them experiencing confusion afterward.

  Recruiting Chinese Academy of Medical Sciences, Fuwai Hospital · Beijing · NCT06861998

• Low-dose Esketamine for preventing delirium in elderly patients undergoing surgery

  This study is testing if low-dose Esketamine can help prevent confusion after surgery in older adults aged 65 to 90.

  Recruiting at 3 sites Nanfang Hospital, Southern Medical University · Fuzhou, Fujian and 5 other locations · NCT06817239

• Sleep, Cognition, and Pain Bundle versus ERAS‑cardiac to Prevent Delirium After Heart Surgery

  This trial will try a package of sleep improvement, pre-surgery brain exercises on a tablet, and 48 hours of IV acetaminophen alongside standard ERAS care to see if it lowers delirium in people 60 and older having planned heart surgery.

  Recruiting at 3 sites Phase 3 Beth Israel Deaconess Medical Center · Boston, Massachusetts and 2 other locations · NCT06721819

• Using brain stimulation to reduce delirium after hip surgery in older patients

  This study is testing if a type of brain stimulation can help older patients avoid confusion after hip surgery.

  Recruiting Huazhong University of Science and Technology · Taiyuan, Shanxi · NCT06678529

• Using liraglutide to prevent delirium in elderly diabetic patients after heart surgery

  This study is testing if liraglutide can help prevent confusion after heart surgery in older diabetic patients.

  Recruiting Phase 3 The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Nanjing, Jiangsu · NCT06361238

• Comparing light and deep anesthesia effects on postoperative delirium and cognition in older adults

  This study is testing if using lighter anesthesia during major surgery can help older adults avoid confusion and memory problems afterward.

  Recruiting at 2 sites Auckland City Hospital · Grafton, Auckland and 2 other locations · NCT06268080

• Early activation and sleep-promoting routines to reduce delirium after CABG

  We will test whether early occupational therapy combined with sleep-promoting routines (DREAMS-OT) can reduce delirium in adults undergoing elective CABG surgery.

  Recruiting National University Hospital, Singapore · Singapore · NCT06107517

• Assessing sleep and circadian rhythms in older adults after major orthopedic surgery

  This study is testing how sleep patterns and certain biological markers in older adults after major orthopedic surgery can help us understand the risk of confusion and memory problems afterward.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT06052397

Related topics

Quick answers

How many Delirium - Postoperative clinical trials are recruiting right now?

23, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in China (10 trials), Singapore (3 trials), United States (3 trials), Denmark (2 trials), New Zealand (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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