Improving outcomes for hip fracture patients with heart injury through faster surgery
Official title: HIP fracture Accelerated surgical TreaTment And Care tracK-2 (HIP ATTACK-2) trial
Funded at University of Maryland Baltimore · NIH-10673739 · Data updated 2026-11-12
The HIP ATTACK-2 trial is looking to help people with hip fractures and heart issues by comparing faster surgery within six hours of getting to the hospital to regular surgery, to see if getting treated quicker can help them recover better and live a healthier life.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | August 1, 2022 |
| Project end | July 31, 2027 |
| Funding year | 2023 |
| Award (this year) | $982,071 |
| NIH project number | 5U01AR080377-02 |
| Project ID | NIH-10673739 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults who have sustained a hip fracture and have elevated serum troponin levels indicating acute heart injury.
✕Less likely to help
Patients who do not have a hip fracture or those without any signs of acute heart injury may not benefit from this research.
What this research studies
The HIP ATTACK-2 trial aims to enhance the recovery of patients who suffer from hip fractures and also have acute heart injuries. This research will compare the effects of accelerated surgery, performed within six hours of hospital admission, against standard surgical care. By focusing on patients with elevated serum troponin levels, the study seeks to determine if quicker surgical intervention can reduce mortality rates, improve mobility, and enhance overall quality of life. Participants will be monitored for their ability to walk independently and for any complications arising from their treatment.
Why it matters
Potential benefit: If successful, this research could significantly lower the risk of death and improve recovery outcomes for hip fracture patients with heart injuries.
How similar studies have gone: Previous studies have indicated that accelerated surgical interventions can improve outcomes for similar patient populations, suggesting a promising avenue for this trial.
Where this research is happening
-
University of Maryland Baltimore
Baltimore, United States Active
Researchers
- Principal investigator: Slobogean, Gerard — University of Maryland Baltimore
- Study coordinator: Slobogean, Gerard
Related research
Other NIH-funded projects on the same topics.
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MAC-STILA: Safer, gentler anesthesia for hip fracture in older adults
A multi-center trial tests a new anesthesia approach (MAC-STILA) to reduce delirium and other problems after hip-fracture surgery in older adults with dementia.
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HIP ATTACK-2: Faster surgery for hip fracture patients with heart injury
A multicenter trial tests whether operating within 6 hours after hip fracture improves survival and recovery for patients who also have acute heart injury.
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Hip fracture risk in people with chronic kidney disease
A study focused on why hip fractures happen and how to prevent them in people with chronic kidney disease.
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How bones weaken in different ways that lead to hip fractures
This project looks at how differences in bone size, mineral content, and bone area relate to hip fracture risk in older men and women.
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Monitored sedation with local anesthetic injections for older adults with hip fracture
This project compares monitored sedation plus local anesthesia injections to standard general anesthesia for older adults having hip fracture surgery to reduce postoperative delirium.
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Developing a new treatment to improve muscle recovery after hip fractures in older adults
This study is testing a new pill called RT-002 to see if it can help older adults heal better and regain strength after a hip fracture, with the hope of making their recovery easier and improving their overall quality of life.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.