Investigating the link between frailty and inflammation in hip fracture patients

Frailty in Hip Fracture Patients Treated With Surgery; the Role of Simple Inflammatory Biomarkers. An Observational Study

Observational University of Thessaly · NCT06614478

This study is looking to see if older adults with hip fractures who are more frail have higher levels of inflammation in their bodies.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages65 Years and up
SexAll
SponsorUniversity of Thessaly Academic / other
Locations2 sites (Larissa, Thessaly and 1 other locations)
Trial IDNCT06614478 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore the relationship between frailty and inflammatory biomarkers in elderly patients who have suffered hip fractures. It focuses on understanding whether patients with frailty exhibit a higher inflammatory burden as indicated by simple inflammatory biomarkers. The study will include patients aged over 65 years who are able to communicate and are not institutionalized. By analyzing these biomarkers, researchers hope to gain insights into the prognosis of frail hip fracture patients.

Who should consider this trial

Good fit: Ideal candidates for this study are elderly individuals over 65 years old who have suffered a hip fracture and are able to communicate.

Not a fit: Patients with severe cognitive dysfunction, those treated conservatively, or those with pathological fractures may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved prognostic assessments and tailored interventions for frail elderly patients with hip fractures.

How similar studies have performed: While the specific approach of this study may be novel, previous studies have indicated a correlation between frailty and inflammatory markers in similar populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* age \>65 years, ASA PS I-III, non- institutionalized, able to communicate patients

Exclusion Criteria:

* Patients with severe cognitive dysfunction, those treated conservatively, those with pathological fractures and patients who refused to participate

Where this trial is running

Larissa, Thessaly and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions FrailtyHip FractureInflammatory Biomarkers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.