Investigating the link between frailty and inflammation in hip fracture patients
Official title: Frailty in Hip Fracture Patients Treated With Surgery; the Role of Simple Inflammatory Biomarkers. An Observational Study
Run by University of Thessaly · NCT06614478 · Data updated 2026-11-12
This study is looking to see if older adults with hip fractures who are more frail have higher levels of inflammation in their bodies.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | University of Thessaly Academic / other |
| Locations | 2 sites (Larissa, Thessaly and 1 other locations) |
| Status | Recruiting |
| Started | April 1, 2023 |
| Main results expected | February 25, 2027 |
| Study ends | April 12, 2027 |
| Registry record updated | May 5, 2026 |
| Trial ID | NCT06614478 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are elderly individuals over 65 years old who have suffered a hip fracture and are able to communicate.
✕Probably not a fit
Patients with severe cognitive dysfunction, those treated conservatively, or those with pathological fractures may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the relationship between frailty and inflammatory biomarkers in elderly patients who have suffered hip fractures. It focuses on understanding whether patients with frailty exhibit a higher inflammatory burden as indicated by simple inflammatory biomarkers. The study will include patients aged over 65 years who are able to communicate and are not institutionalized. By analyzing these biomarkers, researchers hope to gain insights into the prognosis of frail hip fracture patients.
Why it matters
Potential benefit: If successful, this study could lead to improved prognostic assessments and tailored interventions for frail elderly patients with hip fractures.
How similar studies have gone: While the specific approach of this study may be novel, previous studies have indicated a correlation between frailty and inflammatory markers in similar populations.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age \>65 years, ASA PS I-III, non- institutionalized, able to communicate patients Exclusion Criteria: * Patients with severe cognitive dysfunction, those treated conservatively, those with pathological fractures and patients who refused to participate
Where it's running
-
Larissa University Hospital
Larissa, Thessaly, Greece Recruiting -
Uhl
Larissa, Thessaly, Greece Recruiting
Study contacts
- Study coordinator: Eleni Arnaoutoglou, Professor
- Email: earnaout@gmail.com
- Phone: +302413502952
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Frailty plus Nottingham Hip Fracture Score to predict 90-day death risk after hip surgery
This project will test whether adding a quick frailty check (Clinical Frailty Scale) to the Nottingham Hip Fracture Score helps doctors better predict 90-day death risk for people aged 60 and older having hip fracture surgery.
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Total Intravenous Versus Inhalational Anesthesia in Hip Fracture Surgery
This study compares TIVA with sevoflurane anesthesia in people 65 and older undergoing hip fracture surgery to see which method helps them recover better after surgery.
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Physical Function and Fall Risk in Older Adults in Lalín's Frailty Prevention Program
This study will look at how physical function and fall risk change in people 70 and older who participate in a routine frailty and falls prevention program, by comparing assessments before and after the 8–12 week program.
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Home-based multicomponent exercise program for older adults with osteosarcopenia and frailty
This study tests a home-based exercise program built on the Fogg Behavior Model to see if it improves frailty, muscle strength, physical function, bone density, and quality of life in adults aged 60–85 with osteosarcopenia and frailty.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.