Clinical trial Recruiting at 1 site Observational Ages 65 and up

MDW blood test to predict complications and survival after hip fracture

Official title: The Role of Monocyte Distribution Width (MDW) and Other Inflammatory Biomarkers in the Prediction of Mortality and Morbidity in Patients With Hip Fracture

Run by National and Kapodistrian University of Athens · NCT07350785 · Data updated 2026-11-12

This will test whether a routine blood measure called Monocyte Distribution Width (MDW) can help predict complications or death in people aged 65 and older who have a low-energy hip fracture.

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Quick facts

Study typeObservational
Ages65 Years and up
SexAll
Enrollment100 (estimated)
SponsorNational and Kapodistrian University of Athens
Academic / other
Locations1 site (Kifissia, Attica)
StatusRecruiting
StartedDecember 1, 2024
Main results expectedMarch 1, 2026
Study endsMarch 1, 2026
Registry record updatedJanuary 20, 2026
Trial IDNCT07350785 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are people aged 65 or older admitted to the General Hospital of Attica KAT with a low-energy femoral neck, intertrochanteric, or subtrochanteric hip fracture and available baseline blood tests including MDW.

Probably not a fit

Patients under 65, those with high-energy or pathological hip fractures, or patients treated outside the enrolling hospital are unlikely to benefit from this specific program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will enroll about 100 patients aged 65 and older admitted with low-energy hip fractures at the General Hospital of Attica KAT in Kifissia. MDW, measured as part of a routine complete blood count, will be collected at hospital admission, after surgery, and at additional timepoints during the hospital stay alongside other inflammatory biomarkers. Researchers will compare MDW values to postoperative outcomes including infections, sepsis, other complications, length of stay, and mortality to see if higher MDW predicts worse outcomes. Statistical models will adjust for clinical factors to determine whether MDW adds prognostic value beyond standard tests.

Why it matters

Potential benefit: If successful, MDW could help clinicians identify older hip fracture patients at higher risk for infection or death so they can provide closer monitoring or earlier treatment.

How similar studies have gone: MDW has shown promise in other settings for early detection of infection and sepsis, but its specific use to predict postoperative outcomes after hip fracture is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged ≥65 years
* Admission with low-energy hip fracture (femoral neck, intertrochanteric, or subtrochanteric fracture)
* Admission to General Hospital of Attica KAT
* Availability of baseline laboratory measurements, including complete blood count with monocyte distribution width (MDW) and inflammatory biomarkers

Exclusion Criteria:

* Age \<65 years
* High-energy trauma-related hip fractures
* Pathological fractures

Where it's running

  • Laboratory for Research of the Musculoskeletal System
    Kifissia, Attica, Greece
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.