MDW blood test to predict complications and survival after hip fracture
Official title: The Role of Monocyte Distribution Width (MDW) and Other Inflammatory Biomarkers in the Prediction of Mortality and Morbidity in Patients With Hip Fracture
Run by National and Kapodistrian University of Athens · NCT07350785 · Data updated 2026-11-12
This will test whether a routine blood measure called Monocyte Distribution Width (MDW) can help predict complications or death in people aged 65 and older who have a low-energy hip fracture.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | National and Kapodistrian University of Athens Academic / other |
| Locations | 1 site (Kifissia, Attica) |
| Status | Recruiting |
| Started | December 1, 2024 |
| Main results expected | March 1, 2026 |
| Study ends | March 1, 2026 |
| Registry record updated | January 20, 2026 |
| Trial ID | NCT07350785 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are people aged 65 or older admitted to the General Hospital of Attica KAT with a low-energy femoral neck, intertrochanteric, or subtrochanteric hip fracture and available baseline blood tests including MDW.
✕Probably not a fit
Patients under 65, those with high-energy or pathological hip fractures, or patients treated outside the enrolling hospital are unlikely to benefit from this specific program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study will enroll about 100 patients aged 65 and older admitted with low-energy hip fractures at the General Hospital of Attica KAT in Kifissia. MDW, measured as part of a routine complete blood count, will be collected at hospital admission, after surgery, and at additional timepoints during the hospital stay alongside other inflammatory biomarkers. Researchers will compare MDW values to postoperative outcomes including infections, sepsis, other complications, length of stay, and mortality to see if higher MDW predicts worse outcomes. Statistical models will adjust for clinical factors to determine whether MDW adds prognostic value beyond standard tests.
Why it matters
Potential benefit: If successful, MDW could help clinicians identify older hip fracture patients at higher risk for infection or death so they can provide closer monitoring or earlier treatment.
How similar studies have gone: MDW has shown promise in other settings for early detection of infection and sepsis, but its specific use to predict postoperative outcomes after hip fracture is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged ≥65 years * Admission with low-energy hip fracture (femoral neck, intertrochanteric, or subtrochanteric fracture) * Admission to General Hospital of Attica KAT * Availability of baseline laboratory measurements, including complete blood count with monocyte distribution width (MDW) and inflammatory biomarkers Exclusion Criteria: * Age \<65 years * High-energy trauma-related hip fractures * Pathological fractures
Where it's running
-
Laboratory for Research of the Musculoskeletal System
Kifissia, Attica, Greece Recruiting
Study contacts
- Study coordinator: Efstathios Chronopoulos
- Email: stathi24@yahoo.gr
- Phone: 00306944837793
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.