Condition

Postoperative Pain Management clinical trials and research

• 17Clinical trials
• 2NIH research projects
• 8Countries

Newest Postoperative Pain Management clinical trials

All recruiting trials (17)

• Postoperative Pain Management in Thoracic Surgery

  This study tests how well pain control methods work after thoracic surgery for adults, especially when epidural analgesia isn’t possible.

  Recruiting Hospital Universitario de Gran Canaria Doctor Negrín · Las Palmas de Gran Canaria, Las Palmas · NCT07694141

• Comparison of two chest wall blocks for pain after VATS

  Doctors test whether the rhomboid intercostal plane block or the SPSIP block better relieves pain after video-assisted thoracoscopic surgery in adults.

  Recruiting Cumhuriyet University · Sivas, Merkez and 1 other locations · NCT07524673

• mTLIP versus QIPB for pain relief after lumbar microdiscectomy

  This study will test whether the modified thoracolumbar interfascial plane block (mTLIP) or the quadro-iliac plane block (QIPB) provides better pain relief for adults having lumbar microdiscectomy surgery.

  Recruiting Bursa City Hospital · Bursa, Nilüfer · NCT07480278

• Sensory mapping of two nerve blocks for laparoscopic gallbladder surgery

  We will test whether two regional nerve blocks (External Oblique Plane and Serratus Intercostal Plane) produce different skin numbness patterns in adults having elective laparoscopic gallbladder removal.

  Recruiting Samsun University · Samsun, Ilkadım · NCT07445854

• Dezocine versus nalbuphine with sufentanil for pain control after oral cancer surgery with free-flap reconstruction

  This will see if adding dezocine or nalbuphine to sufentanil reduces pain and complications for adults undergoing oral cancer surgery with free-flap reconstruction.

  Recruiting Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT07401641

• Ultrasound-guided fascial plane blocks to reduce lung problems after major abdominal surgery

  This study will try ultrasound-guided fascial plane blocks to see if they reduce postoperative lung complications in adults aged 65 and older having elective major abdominal surgery.

  Recruiting Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · Yenimahalle, Ankara · NCT07394816

• Erector spinae versus serratus posterior superior intercostal plane nerve blocks for pain after coronary bypass

  This study will test whether an erector spinae plane block or a serratus posterior superior intercostal plane block provides better pain relief and reduces opioid use after elective coronary artery bypass graft surgery in adults aged 45–85.

  Recruiting Kutahya Health Sciences University · Kütahya · NCT07388745

• Suprainguinal fascia iliaca block with or without dexmedetomidine for hip replacement pain

  This trial will test whether adding dexmedetomidine to ropivacaine in a suprainguinal fascia iliaca nerve block helps control pain and delay the first request for pain medication after elective hip replacement.

  Recruiting Phase 4 Rhode Island Hospital · Providence, Rhode Island · NCT07316166

• Anrikefon versus nalbuphine for pain control after eye surgery

  This trial will test whether Anrikefon provides pain relief as well as nalbuphine for adults having eye surgery under general anesthesia.

  Recruiting Phase 4 Zhongshan Ophthalmic Center, Sun Yat-sen University · Guangzhou, Guangdong and 2 other locations · NCT07269106

• Spinal (intrathecal) morphine versus local bupivacaine for recovery after laparoscopic hysterectomy

  This will test whether a single spinal injection of morphine or local bupivacaine given at trocar sites and inside the abdomen better reduces pain and improves recovery for women having elective laparoscopic hysterectomy.

  Recruiting Ataturk University · Erzurum · NCT07232108

• Ear (auricular) vagus nerve stimulation to lower inflammation after long spinal fusion

  This trial will test whether non-invasive ear-based vagus nerve stimulation can lower inflammation, improve blood sugar control, and reduce pain after long-segment spinal fusion surgery.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT07218133

• Acupuncture for pain after total knee replacement

  This project will try acupuncture to reduce short-term pain, opioid use, and inflammation after elective total knee replacement in adults.

  Recruiting Fondazione IRCCS Policlinico San Matteo di Pavia · Pavia, Pavia · NCT07123805

• Remimazolam versus Midazolam for sedation and early thinking recovery in older adults having orthopedic surgery

  This will test whether remimazolam or midazolam gives better sedation and faster early recovery of thinking and memory for people 65 and older undergoing orthopedic surgery with regional anesthesia.

  Recruiting Phase 3 Romanian Society for Enteral and Parenteral Nutrition · Bucharest · NCT07113483

• Lidocaine plus dexmedetomidine during laparoscopic bariatric surgery to reduce pain, inflammation, and oxidative stress

  This trial will try giving an intravenous combination of lidocaine and dexmedetomidine during laparoscopic bariatric surgery in adults with obesity to see if it lowers pain, inflammation, and oxidative stress after surgery.

  Recruiting at 2 sites Phase 4 Instituto Mexicano del Seguro Social · Mexico City, Mexico City and 1 other locations · NCT07073846

• Comparing Iliopsoas (IPB) and Pericapsular Nerve Group (PENG) blocks for pain control and recovery after total hip replacement

  This trial will try whether the iliopsoas plane block (IPB) works as well as the PENG block to reduce pain and help recovery after hip replacement in adults having surgery under spinal anesthesia.

  Recruiting University of Liege · Liège · NCT06964282

• Using magnesium and ketamine to manage pain during hysteroscopy

  This study is testing if magnesium and ketamine can help reduce pain for people having a hysteroscopy or D&C, compared to a placebo.

  Recruiting Phase 4 Corewell Health East · Royal Oak, Michigan · NCT06745388

• Pain management technique for robotic thymectomy

  This study is testing a new pain management technique to see if it can help people having robotic thymectomy surgery feel less pain and recover better.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome · NCT06545409

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Using virtual reality and biofeedback to manage pain after surgery in kids

  This study is exploring a fun new way to help kids and teens feel better after surgery by using virtual reality and biofeedback, so they can manage their pain on their own and recover more comfortably.

  NIH research Nemours Children's Hospital, Delaware · Wilmington, United States · NIH-11044480

• Using advanced computer tools to improve pain management after surgery

  This study is looking at how to make pain relief after surgery better by using smart computer tools to understand patient records, so we can find out who might need different kinds of pain management to feel their best while they recover.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-10684876

Related topics

Quick answers

How many Postoperative Pain Management clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in Turkey (Türkiye) (6 trials), United States (3 trials), Italy (2 trials), China (2 trials), Belgium (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 4, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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