Condition
Hematopoietic and Lymphatic System Neoplasm clinical trials and research
As of November 12, 2026, Find a Trial lists 55 Hematopoietic and Lymphatic System Neoplasm clinical trials that are recruiting, at sites in 3 countries (most in United States (55), Puerto Rico (2), Canada (1)). By phase: Phase 2 (7), Phase 1 (3), Phase 3 (2), Early Phase 1 (1). The most active sponsors are Mayo Clinic (18), City of Hope Medical Center (8), Fred Hutchinson Cancer Center (7). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 55Clinical trials
- 3Countries
Newest Hematopoietic and Lymphatic System Neoplasm clinical trials
All recruiting trials (55)
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See if virtual informed consent methods help people decide to join cancer research
This trial tests whether virtual human communicators and different consent messages can influence cancer patients’ understanding and willingness to participate in research.
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AI-powered supportive care chatbot for young adult cancer survivors
A chatbot driven by artificial intelligence is tested to help young adult cancer survivors manage symptoms and care needs after treatment.
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Telehealth pharmacist-led opioid education for cancer patients
This pilot tests a telehealth group education session led by a palliative care pharmacist to help adults with cancer use opioids more safely and effectively.
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Mindfulness program to help with symptoms in chronic graft-versus-host disease
A mindfulness-based program is being tested to see if it can reduce patient-reported symptoms for adults with chronic graft-versus-host disease after a stem cell transplant.
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Non-invasive brain stimulation to help chemotherapy-induced nerve problems in cancer survivors
This trial tests whether a gentle brain stimulation method (tDCS) can help reduce numbness, tingling, and pain from CIPN in cancer survivors who are not currently in treatment.
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High Fiber Program to see if more fiber helps patients after an allogeneic stem cell transplant
This program tests whether a high-fiber diet can help adults undergoing allogeneic hematopoietic cell transplant eat more fiber and feel better.
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Post-transplant dental cleaning to prevent chronic graft-versus-host disease
This will try a dental cleaning about 28 days after an allogeneic stem cell transplant to see if it lowers the chance of chronic graft-versus-host disease in adult transplant recipients.
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Ambient sensor rooms to spot early problems in hospitalized cancer patients
This test will try whether special hospital rooms with cameras, microphones, and temperature sensors can help staff spot early delirium, falls, sleep problems, or mood changes in adults hospitalized with cancer.
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Voices: sharing messages of wisdom and hope during illness
This project will see if recording semi-structured interviews with adult cancer patients (and optional caregivers) affects patients' sense of dignity and caregiver support.
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Virtual LASO-3 diet program to ease chemotherapy-related numbness and tingling
This trial tests whether a virtual diet program that lowers added sugar and increases fiber and omega-3s can help cancer survivors who have numbness, tingling, or pain after neurotoxic chemotherapy.
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Culturally tailored patient navigation to shorten time from cancer diagnosis to treatment for American Indian and Alaska Native people in rural California
This project will try a culturally tailored patient navigation program to shorten delays between cancer diagnosis and treatment for American Indian and Alaska Native adults living in rural California.
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How doctors' behaviors affect distress during radiation therapy
This study will see if certain physician behaviors during radiation therapy change how much distress adults with cancer experience.
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Interest in integrative oncology services at USC Norris Cancer Center
This project will see if adult patients with solid tumors or blood cancers at USC Norris and Keck HC3 are interested in and able to use integrative oncology services and what barriers might limit participation.
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Virtual Mindfulness-Based Stress Reduction program for underserved Minnesota cancer patients
This program tests if a virtual mindfulness-based stress reduction (MBSR) course can reduce emotional distress and improve mental well-being for cancer patients in underserved or rural parts of Minnesota.
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Web-based CONNECT toolkit to reduce emotional distress and anxiety in rural older cancer survivors
We will test whether CONNECT, a web-based toolkit, can help reduce cancer-related emotional distress and anxiety in rural adults over 65 who have finished cancer treatment.
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In-home cancer treatment with remote specialist support for patients in the Florida Panhandle
This program will try giving standard cancer treatments at home to people living in the Florida Panhandle and nearby areas to see if they prefer it and have better treatment satisfaction.
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Immune Cells in Blood and Tissues After Allogeneic Transplant and Chronic GVHD
This study tests whether immune cells in blood and other samples differ between people who develop chronic GVHD after an allogeneic transplant and those who don’t.
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L-theanine for relaxation and mood support in cancer patients on surveillance
This trial tests whether taking 200 mg of L-theanine once or twice daily for six weeks can help relaxation and mood in adult cancer patients who have finished treatment and are in surveillance.
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Viewing your street in virtual reality: original versus digitally altered opposite streetscape
This test shows adult neighborhood residents short virtual reality scenes of either their actual street or a digitally altered ‘opposite’ version to see if those views change stress, emotion, and physiological responses.
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Different types of massage to reduce anxiety during chemotherapy infusion
This trial tests whether 30-minute massages to different body areas during chemo infusions can reduce anxiety in adult cancer patients who report at least moderate anxiety.
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Telephone coaching to help people with advanced cancer and their support person plan for end-of-life care
This program tests whether two phone coaching sessions help people with advanced cancer and their support person have end-of-life conversations and complete advance directives.
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Virtual community health educator to boost referrals to cancer clinical programs for patients and caregivers
This study tests whether a photo-realistic virtual community health educator can help cancer patients and their caregivers get more referrals to cancer clinical programs.
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Aromatherapy with peppermint, lavender, or ginger to ease anxiety and nausea during outpatient chemotherapy infusions
This research will test whether inhaling peppermint, ginger, or lavender essential oils can reduce nausea and anxiety for adults getting outpatient chemotherapy infusions.
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Using a web tool (PACT) and patient navigation to improve goals-of-care conversations for hematopoietic cell transplant survivors
This program tries the PACT website, a trained patient navigator, or both to help blood-cancer survivors who had a hematopoietic cell transplant have clearer advance care planning and goals-of-care conversations.
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Biomarker-guided ruxolitinib to prevent chronic graft-versus-host disease after allogeneic stem cell transplant
This study tests whether giving ruxolitinib based on blood GVHD biomarkers around day 100 after an allogeneic stem cell transplant can prevent chronic GVHD in adults at higher biomarker risk.
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CMV Triplex vaccine to boost immunity and prevent CMV after haploidentical stem cell transplant
This trial tests whether giving a CMV-MVA Triplex vaccine to donors and/or recipients, with or without the antiviral letermovir, can boost CMV immunity and prevent CMV viremia in people having haploidentical stem cell transplants.
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Guided meditation to reduce anxiety before cancer surgery
This study tests if listening to a guided meditation can help reduce anxiety in patients getting ready for cancer surgery compared to wearing noise-canceling headphones.
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Virtual solution-focused brief therapy for emotional distress in adolescent and young adult cancer survivors
This project tests whether short, virtual solution-focused therapy helps adolescents and young adults (ages 15–39) who are cancer survivors reduce anxiety and depression compared with enhanced usual care.
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Spinal injections of cytarabine, methotrexate, and hydrocortisone to prevent severe CAR T neurotoxicity
This phase II test tries whether giving intrathecal cytarabine, methotrexate, and hydrocortisone around day 4 (with a day 7 hydrocortisone if no symptoms) can prevent severe neurotoxicity in adults receiving Yescarta or Tecartus CAR T-cell therapy.
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Memory and physical activity in adolescent and young adult cancer survivors
This project will see if physical activity is linked to thinking and memory in adults who were treated for cancer between ages 15 and 39.
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Remdesivir for RSV in immunocompromised adults
This trial tests whether a short course of intravenous remdesivir can help adults whose immune systems are weakened by cellular or bispecific antibody therapies recover from upper respiratory RSV infection.
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Using acupressure to reduce anxiety in cancer patients undergoing treatment
This study tests if acupressure can help reduce anxiety and nausea in cancer patients undergoing chemotherapy and improve their overall quality of life.
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Q702 to treat blood cancers
This Phase 1 trial will test whether the oral drug Q702 is safe, tolerable, and what dose works best for adults with certain blood cancers who have failed or are not eligible for standard treatments.
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Telehealth support for caregivers of cancer patients
This study tests if a telehealth support program can help caregivers of cancer patients feel less stressed about money and depression while improving their confidence and satisfaction in caring for their loved ones.
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Modeling cancer treatment side effects using patient blood samples
This study is trying to see how cancer treatments affect the body by using blood samples from patients to create special cells that can help researchers understand side effects like heart and nerve damage.
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Evaluating high ammonia levels in patients treated with Erwinia asparaginase
This study is testing how many patients with acute lymphoblastic leukemia treated with Erwinia asparaginase develop high ammonia levels and who might be at risk for this problem.
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Genetic testing to prevent cancer in Indigenous American communities
This study is trying to see if genetic testing can help prevent cancer and improve treatment for Indigenous American communities in the Southwest.
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Community exercise and nutrition program for cancer survivors
This study is testing a 12-week exercise and nutrition program to see if it can help cancer survivors feel healthier and improve their quality of life.
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Observing sex differences in symptoms during cancer immunotherapy
This study looks at the different symptoms men and women experience during cancer immunotherapy to see how their reports match up with what doctors observe.
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Using triptorelin to protect ovaries in young cancer patients during chemotherapy
This study is testing if triptorelin can help protect the ovaries of young cancer patients under 40 during chemotherapy to see if it helps maintain their fertility and overall health later on.
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Using siltuximab to prevent severe side effects during cancer treatment
This study is testing if the drug siltuximab can help prevent severe side effects in cancer patients who are getting immune therapy again.
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Early detection of cognitive side effects from immunotherapy
This project tests whether an automated toolkit called SALSA can find early cognitive side effects in adults receiving CAR-T immunotherapy.
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Culturally-tailored mobile and social media program to increase physical activity in Hispanic/Latino adolescent and young adult childhood cancer survivors.
This project will test whether a culturally tailored home-based physical activity program delivered via mobile tools and social media can help Hispanic/Latino adolescent and young adult childhood cancer survivors become more active.
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Using Wisconsin ginseng to reduce cancer-related fatigue
This study is testing if Wisconsin ginseng can help reduce fatigue in cancer patients compared to a placebo over eight weeks.
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Identifying heart risks in cancer patients after chemotherapy
This study is trying to find out why some cancer patients have heart problems after chemotherapy while others don't, by looking at their blood samples and medical records.
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Using creative arts to help children with cancer
This study is testing if doing creative arts like drawing and painting can help children with cancer feel better and improve their quality of life compared to just watching videos.
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Validation of blood and urine tests for early cancer detection
This study is testing if blood and urine tests can help find some of the deadliest cancers earlier in people who have them compared to those who don’t.
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Comparing different telephone methods for managing symptoms during cancer treatment
This study is testing three different phone-based support methods to see which one helps cancer patients manage their symptoms and feelings better during treatment.
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Evaluating a new AI tool for radiation therapy planning
This study tests a new AI tool that helps medical staff at Mayo Clinic plan radiation therapy by automatically outlining important areas on CT scans to see if it makes their job easier and more accurate.
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Using cord blood transplant and chemotherapy to treat high-risk blood cancers
This study is testing if combining umbilical cord blood transplants with certain chemotherapy treatments can help people with high-risk blood cancers do better and have fewer side effects.
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Combining Temozolomide and M1774 to Treat Advanced Cancer
This study is testing a combination of two cancer drugs, temozolomide and M1774, to see if they can help people with advanced metastatic cancers feel better and improve their treatment outcomes.
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Reduced-intensity conditioning to lower treatment-related mortality in stem cell transplant patients
This study is testing a new way to prepare patients for a stem cell transplant to see if it can lower the risk of serious treatment-related complications.
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Oral fiber supplementation for patients receiving stem cell transplants
This study is testing if taking extra fiber can help people getting stem cell transplants feel better and improve their gut health during treatment.
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Testing genetic markers for early detection of myeloid cancers and bone marrow failure
This study is testing if looking for specific genetic markers in blood and tissue samples can help find myeloid cancers and bone marrow issues earlier in people who show early signs but aren't diagnosed yet.
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Collecting and storing tissue and blood samples from cancer patients
This study is collecting and storing blood and tissue samples from cancer patients to help researchers create better models for understanding cancer and testing new treatments.
Related topics
Quick answers
How many Hematopoietic and Lymphatic System Neoplasm clinical trials are recruiting right now?
55, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (55 trials), Puerto Rico (2 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 7, Phase 1: 3, Phase 3: 2, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.