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Clinical trial Recruiting at 1 site Observational Ages 18 and up

Voices: sharing messages of wisdom and hope during illness

Official title: Voices: Messages of Wisdom and Hope in the Face of Illness

Run by Mayo Clinic · NCT07381179 · Data updated 2026-11-12

This project will see if recording semi-structured interviews with adult cancer patients (and optional caregivers) affects patients' sense of dignity and caregiver support.

More Malignant Solid Neoplasm trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment40 (estimated)
SponsorMayo Clinic
Academic / other
Locations1 site (Rochester, Minnesota)
StatusRecruiting
StartedNovember 13, 2025
Main results expectedDecember 13, 2027
Study endsDecember 13, 2027
Registry record updatedFebruary 2, 2026
Trial IDNCT07381179 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (age ≥18) with a chronic or progressive hematologic or solid malignancy who can complete a ~60-minute recorded interview and, if desired, involve a primary caregiver are ideal candidates.

Probably not a fit

Patients who cannot tolerate a 60-minute recording because of uncontrolled illness or who lack capacity to consent are unlikely to benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project invites adult patients with hematologic or solid tumors and, if they choose, their primary caregivers to participate in recorded interviews. Participants complete a roughly 60-minute semi-structured recording and a single follow-up recording, complete surveys including the Patient Dignity Impact Scale, and allow review of their medical records. The main outcome is change in dignity impact scores before and after the recordings. All activities are conducted at Mayo Clinic in Rochester, Minnesota.

Why it matters

Potential benefit: If successful, this could identify ways to preserve patient dignity and target additional support for patients and caregivers during treatment.

How similar studies have gone: Prior dignity-therapy and recorded legacy interventions in palliative care have shown improvements in dignity and psychological well-being in some studies.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Age ≥ 18 years
* Diagnosis of chronic or progressive illness with a primary caregiver, should patient wish to involve one
* Willing and able to participate in a semi-structured recording lasting approximately 60 minutes. Dyad recordings conducted for participants who elect to involve a caregiver
* Willing and able to participate in a single follow-up recording. Dyad follow up recordings conducted for participants who elect to involve a caregiver

Exclusion Criteria:

* Uncontrolled and/or intercurrent illness which limits participation in study recording
* Vulnerable populations: persons lacking capacity for understanding participation in this study

Where it's running

  • Mayo Clinic in Rochester
    Rochester, Minnesota, United States     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov ↗ Find more trials like this →
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.