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Clinical trial Recruiting at 2 sites Interventional

Culturally tailored patient navigation to shorten time from cancer diagnosis to treatment for American Indian and Alaska Native people in rural California

Official title: Developing a Culturally Informed Patient Navigation Program to Reduce Delays From Diagnosis to Treatment for Native Americans in a Rural Setting

Run by University of Southern California · NCT07332312 · Data updated 2026-11-12

This project will try a culturally tailored patient navigation program to shorten delays between cancer diagnosis and treatment for American Indian and Alaska Native adults living in rural California.

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Quick facts

Study typeInterventional
SexAll
Enrollment71 (estimated)
SponsorUniversity of Southern California
Academic / other
Locations2 sites (Bishop, California and 1 other locations)
StatusRecruiting
StartedApril 17, 2026
Main results expectedNovember 13, 2027
Study endsNovember 13, 2028
Registry record updatedMay 11, 2026
Trial IDNCT07332312 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal participants are American Indian and Alaska Native adults living in the Toiyabe Indian Health Program catchment who have any type of cancer at any stage, plus AIAN community members and healthcare staff who participate in co-design activities.

Probably not a fit

People who are not AIAN, who live outside the TIHP catchment area, or whose delays are due to factors unrelated to navigation (for example, clinical contraindications) may not benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The team will co-design a Community-Focused Patient Navigation (CFPN) program with American Indian and Alaska Native (AIAN) community members using community advisory boards, focus groups, and key informant interviews. CFPN navigators will work directly with patients across the cancer care continuum to create individualized treatment plans, provide care coordination, and offer opioid misuse education. Implementation and impact will be measured using PRISM and RE-AIM frameworks alongside Indigenous evaluation practices, tracking reach, timeliness, and maintenance of navigation services. The program will be delivered through Toiyabe Indian Health Program sites in Bishop and coordinated with USC Norris Comprehensive Cancer Center in Los Angeles.

Why it matters

Potential benefit: If successful, the program could reduce time to treatment, improve access to culturally responsive care, and potentially improve cancer outcomes for AIAN patients in rural areas.

How similar studies have gone: Prior patient navigation programs have reduced delays and improved adherence in other populations, but culturally tailored navigation specifically for rural AIAN communities is relatively novel and less well studied.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* CAB: Self-identify as AIAN or have experience working with the AIAN community
* CAB: Are 18 years or older
* CAB: Live within Toiyabe Indian Health Program (TIHP) catchment area(s)
* CAB: Are either a cancer patient/survivor/caregiver and/or a family member of an individual(s) affected by cancer, OR a Board member (ex: Tribal Health Board or Elders Board)
* FOCUS GROUP: Self-identify as AIAN or a family member of an AIAN individual affected by cancer
* FOCUS GROUP: Are 18 years or older
* FOCUS GROUP: Live within TIHP catchment area(s)
* FOCUS GROUP: Are either a cancer patient/survivor/caregiver and/or a family member of an individual(s) affected by cancer, OR a Board member (ex: Tribal Health Board or Elders Board)
* KII: Be a TIHP healthcare staff member
* KII: Be 18 years or older
* KII: Work with AIAN cancer patients in TIHP catchment area
* CFPN PROGRAM IMPLEMENTATION: Have any type of cancer, are in any treatment stage along the cancer continuum
* CFPN PROGRAM IMPLEMENTATION: Self-identify as AIAN or be a TIHP patient
* CFPN PROGRAM IMPLEMENTATION: Live in the TIHP service area
* CFPN PROGRAM IMPLEMENTATION: Receive cancer-related services from TIHP

Exclusion Criteria:

* FOCUS GROUP: Individual with no experience with cancer either as a patient or know someone who is/was a cancer patient at TIHP
* CFPN PROGRAM IMPLEMENTATION: Not a TIHP patient
* CFPN PROGRAM IMPLEMENTATION: Does not currently have cancer or has not previously had cancer

Where it's running

  • Toiyabe Indian Health Project
    Bishop, California, United States     Recruiting
  • USC / Norris Comprehensive Cancer Center
    Los Angeles, California, United States     Recruiting

Study contacts

  • Principal investigator: Claradina Soto — University of Southern California

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.