Using acupressure to reduce anxiety in cancer patients undergoing treatment

Acupressure for Anxiety: A Randomized Controlled Trial of an Acupressure Intervention for Patients Receiving Cancer-Directed Therapy

Not applicable Interventional Mayo Clinic · NCT06723041

This study tests if acupressure can help reduce anxiety and nausea in cancer patients undergoing chemotherapy and improve their overall quality of life.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment78 (estimated)
Ages18 Years and up
SexAll
SponsorMayo Clinic Academic / other
Drugs / interventionschemotherapy
Locations1 site (Rochester, Minnesota)
Trial IDNCT06723041 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness of acupressure in alleviating anxiety in patients receiving chemotherapy for cancer. Participants are randomly assigned to either receive true acupressure or sham acupressure, with the option to learn self-administered acupressure techniques. The study aims to assess both the immediate effects of nurse-applied acupressure and the long-term benefits of self-applied techniques. Additionally, it evaluates whether acupressure can help reduce chemotherapy-related nausea and improve overall quality of life.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who are diagnosed with cancer and undergoing systemic antineoplastic therapy.

Not a fit: Patients who are not currently undergoing chemotherapy or who do not experience significant anxiety may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could provide a non-pharmacological method for cancer patients to manage anxiety and improve their quality of life during treatment.

How similar studies have performed: Previous studies have shown that acupressure can effectively reduce anxiety in various contexts, suggesting potential success for this approach in cancer patients.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* NURSE-LED INTERVENTION: Age \>= 18 years and be diagnosed with cancer
* NURSE-LED INTERVENTION: Undergoing systemic, antineoplastic therapy
* NURSE-LED INTERVENTION: Ability to provide oral consent
* NURSE-LED INTERVENTION: Willingness to undergo a nurse-led acupressure intervention
* NURSE-LED INTERVENTION: Willingness and ability to complete pre- and post-intervention questionnaires in English
* NURSE-LED INTERVENTION: Report acute anxiety as a 5 or higher on a scale for 0 (no anxiety) to 10 (severe anxiety)
* SELF-ADMINISTRATION INTERVENTION: Age \>= 18 years and be diagnosed with cancer
* SELF-ADMINISTRATION INTERVENTION: Undergoing systemic, antineoplastic therapy
* SELF-ADMINISTRATION INTERVENTION: Ability to provide oral consent
* SELF-ADMINISTRATION INTERVENTION: Willingness to undergo a nurse-led acupressure intervention
* SELF-ADMINISTRATION INTERVENTION: Willingness and ability to complete pre- and post-intervention questionnaires in English
* SELF-ADMINISTRATION INTERVENTION: Report acute anxiety as a 5 or higher on a scale for 0 (no anxiety) to 10 (severe anxiety)
* SELF-ADMINISTRATION INTERVENTION: Reports 2+/day anxiety episodes at home
* SELF-ADMINISTRATION INTERVENTION: Interested in learning self-administered acupressure

Exclusion Criteria:

* Prior experiences with acupressure, or training in acupressure points

Where this trial is running

Rochester, Minnesota

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.