Clinical trial Recruiting at 1 site Observational Ages 18 and up

Memory and physical activity in adolescent and young adult cancer survivors

Official title: Investigating Memory and Physical Activity After Cancer Treatment in Survivors of Adolescent and Young Adult Cancers

Run by Mayo Clinic · NCT06880861 · Data updated 2026-11-12

This project will see if physical activity is linked to thinking and memory in adults who were treated for cancer between ages 15 and 39.

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Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment150 (estimated)
SponsorMayo Clinic
Academic / other
Locations1 site (Scottsdale, Arizona)
StatusRecruiting
StartedJuly 1, 2025
Main results expectedDecember 15, 2026
Study endsDecember 15, 2026
Registry record updatedOctober 2, 2026
Trial IDNCT06880861 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18+ whose primary cancer was diagnosed between ages 15 and 39, who are ambulatory, English-speaking, willing to complete study tasks, and have a desktop or laptop with reliable internet are ideal candidates.

Probably not a fit

People whose only cancer was nonmelanoma skin cancer, those diagnosed outside the 15–39 age window, those without reliable computer/internet access, or those with gross motor impairments preventing ambulation may not be eligible or likely to benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study of adults whose primary cancer diagnosis occurred when they were 15–39 years old, designed to examine relationships among physical activity, thinking, and memory after treatment. Participants must be 18 or older, English-speaking, ambulatory, and able to complete study tasks on a desktop or laptop with reliable internet. Data will be collected non-interventionally using computerized cognitive tests, self-report measures, and measures of physical activity (device- or questionnaire-based). The Mayo Clinic in Arizona (Scottsdale) is the lead site for enrollment.

Why it matters

Potential benefit: If successful, the findings could reveal links between physical activity and cognitive health in AYA survivors that inform future efforts to improve memory and thinking.

How similar studies have gone: Previous research in adult cancer survivors has linked higher physical activity to better cognitive outcomes, but evidence focused specifically on adolescent and young adult survivors remains limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults (aged 18+ years)
* Primary diagnosis of cancer when 15-39 years-old
* Access to a desktop computer or laptop with reliable internet access
* No gross motor impairments that prohibit ambulation
* Willing to complete study requirements
* English speaking

Exclusion Criteria:

* Diagnosed with nonmelanoma skin cancer only
* Not diagnosed with cancer in adolescent and young adult (AYA) age range of 15-39 years
* Scheduled travel during the study period that is not indicative of individual's normal schedule

Where it's running

  • Mayo Clinic in Arizona
    Scottsdale, Arizona, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.