Genetic testing to prevent cancer in Indigenous American communities
Official title: Journey to Understanding - American Indian Peoples Engagement in Cancer Research Arizona (JUNIPER)
Run by Mayo Clinic · NCT06569316 · Data updated 2026-11-12
This study is trying to see if genetic testing can help prevent cancer and improve treatment for Indigenous American communities in the Southwest.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Scottsdale, Arizona) |
| Status | Recruiting |
| Started | September 27, 2024 |
| Main results expected | August 31, 2027 |
| Study ends | August 31, 2027 |
| Registry record updated | July 29, 2026 |
| Trial ID | NCT06569316 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include Indigenous American adults aged 18 and older who are currently undergoing cancer treatment or are cancer survivors.
✕Probably not a fit
Patients who are under 18 years of age or unable to provide informed consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial focuses on understanding genetic changes associated with various cancers in Indigenous American populations in the Southwest. It aims to improve cancer screening, precision prevention, and therapeutic interventions by engaging with cancer patients and survivors from these communities. The study involves collecting blood, saliva, and tissue samples for genetic testing, while also ensuring culturally appropriate methods for participant engagement and data collection. The ultimate goal is to translate findings into better cancer outcomes for Indigenous Americans, who face significant health disparities.
Why it matters
Potential benefit: If successful, this study could lead to improved cancer screening and treatment options for Indigenous American populations.
How similar studies have gone: Other studies have shown success in using genetic testing to improve cancer outcomes, but this approach is particularly novel in the context of Indigenous American populations.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or female adults \>= 18 years of age * Cancer patient undergoing active treatment or a cancer survivor * Self-identify as American Indian Exclusion Criteria: * Unable to provide informed consent * Individuals who are under 18 years of age * Prisoners
Where it's running
-
Mayo Clinic in Arizona
Scottsdale, Arizona, United States Recruiting
Study contacts
- Principal investigator: Jewel Samadder, MD — Mayo Clinic
- Study coordinator: Clinical Trials Referral Office
- Email: mayocliniccancerstudies@mayo.edu
- Phone: 855-776-0015
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
See if virtual informed consent methods help people decide to join cancer research
This trial tests whether virtual human communicators and different consent messages can influence cancer patients’ understanding and willingness to participate in research.
-
AI-powered supportive care chatbot for young adult cancer survivors
A chatbot driven by artificial intelligence is tested to help young adult cancer survivors manage symptoms and care needs after treatment.
-
Telehealth pharmacist-led opioid education for cancer patients
This pilot tests a telehealth group education session led by a palliative care pharmacist to help adults with cancer use opioids more safely and effectively.
-
Mindfulness program to help with symptoms in chronic graft-versus-host disease
A mindfulness-based program is being tested to see if it can reduce patient-reported symptoms for adults with chronic graft-versus-host disease after a stem cell transplant.
-
Non-invasive brain stimulation to help chemotherapy-induced nerve problems in cancer survivors
This trial tests whether a gentle brain stimulation method (tDCS) can help reduce numbness, tingling, and pain from CIPN in cancer survivors who are not currently in treatment.
-
Ambient sensor rooms to spot early problems in hospitalized cancer patients
This test will try whether special hospital rooms with cameras, microphones, and temperature sensors can help staff spot early delirium, falls, sleep problems, or mood changes in adults hospitalized with cancer.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.