See if virtual informed consent methods help people decide to join cancer research
Official title: Exploring Health Communication Message Factors That Influence Cancer Research Recruitment
Run by Mayo Clinic · NCT07805083 · Data updated 2026-11-12
This trial tests whether virtual human communicators and different consent messages can influence cancer patients’ understanding and willingness to participate in research.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Jacksonville, Florida) |
| Status | Recruiting |
| Started | July 21, 2026 |
| Main results expected | July 20, 2027 |
| Study ends | July 20, 2029 |
| Registry record updated | September 8, 2026 |
| Trial ID | NCT07805083 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older who speak English and can consent, who are White or Black, and reside in the United States, with access to Mayo Clinic in Florida.
✕Probably not a fit
Participants who are not influenced by the consent format or who are not considering research participation may not experience direct benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study explores perceptions of virtual agents used in research recruitment and compares various informed consent approaches. Researchers will present participants with different ICF formats and videos to see how these options affect decision-making. The study uses an educational cancer intervention to gauge understanding and comfort with the consent process. Participants will be adults (18+) who speak English and are patients or prospective participants at Mayo Clinic in Florida.
Why it matters
Potential benefit: If successful, the approach could make the consent process clearer and more engaging for cancer patients considering research participation.
How similar studies have gone: Previous work in consent methods suggests tailoring consent delivery can affect understanding and willingness to participate, though novel virtual agents are being evaluated.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Able to speak, read, or understand English sufficiently to provide informed consent * 18 years of age or older * White or Black * Living in the United States Exclusion Criteria: * Unable to speak, read, or understand English sufficiently to provide informed consent * Inability on the part of the patient to understand the informed consent or be compliant with the protocol
Where it's running
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Mayo Clinic in Florida
Jacksonville, Florida, United States Recruiting
Study contacts
- Principal investigator: Janice L. Krieger, PhD — Mayo Clinic
- Study coordinator: ETCH Lab
- Email: ETCH@mayo.edu
- Phone: 904-953-5375
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.