Viewing your street in virtual reality: original versus digitally altered opposite streetscape

Piloting a Virtual Reality-Based, Randomized Controlled Trial of Psychosocial Responses to Neighborhood Physical Disorder

Not applicable Interventional Ohio State University Comprehensive Cancer Center · NCT07216534

This test shows adult neighborhood residents short virtual reality scenes of either their actual street or a digitally altered ‘opposite’ version to see if those views change stress, emotion, and physiological responses.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment32 (estimated)
Ages18 Years and up
SexAll
SponsorOhio State University Comprehensive Cancer Center Academic / other
Locations1 site (Columbus, Ohio)
Trial IDNCT07216534 on ClinicalTrials.gov

What this trial studies

Participants will have their residence photographed and then attend an in-person ~2-hour session at Ohio State University where they wear a VR headset and view short (3–5 minute) virtual scenes of their streetscape presented either as a digital twin or as a digitally manipulated opposite with respect to physical disorder indicators. The study uses a crossover design so participants experience both VR conditions while researchers record sympathetic autonomic measures (heart rate variability and skin conductance), eye gaze density, and self-report measures (Self-Assessment Manikin and state anxiety). Investigators will also record frequency and pattern of short-term VR side effects and examine whether side effects change over repeated sessions or differ by condition. Analyses will adjust for covariates to explore which participant or neighborhood factors influence physiological and psychosocial responses.

Who should consider this trial

Good fit: Adults aged 18 or older who live at the photographed residence at least four nights per week, can read English, can wear a VR headset, live in a selected study neighborhood, and can attend an in-person visit at OSU are ideal candidates.

Not a fit: People who are pregnant, have epilepsy or other conditions preventing VR use, have significant visual or mobility impairments, or who do not live in the selected neighborhoods or cannot travel to Columbus, Ohio, are unlikely to benefit or to be eligible.

Why it matters

Potential benefit: If successful, the results could help show how visible neighborhood conditions influence stress and inform low-cost interventions or design changes to improve well-being.

How similar studies have performed: Previous VR research has shown short virtual-environment exposures can change mood and physiological stress markers, but applying personalized digital twins versus digitally opposite streetscapes is a relatively novel approach with limited prior evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults 18+
* Must currently live (4+ night/week) at the residence being studied. Only one resident per household will be selected
* Must understand and be able to read English
* Must agree to have residence photographed
* Must be able to wear a VR head mounted display
* Must live in neighborhood that has been selected for study
* Must be willing and able to attend an approximately 2 hour in-person visit on Ohio State University (OSU) campus

Exclusion Criteria:

* Pregnant women
* Visual or mobility impairment
* Cannot have epilepsy or other condition that would inhibit them from being able to use a VR headset

Where this trial is running

Columbus, Ohio

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hematopoietic and Lymphatic System NeoplasmMalignant Solid NeoplasmPsychiatric Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.