Condition

Chronic Graft Versus Host Disease clinical trials and research

• 19Clinical trials
• 23Countries

Newest Chronic Graft Versus Host Disease clinical trials

All recruiting trials (19)

• Belumosudil vs Best Available Therapy for chronic graft-versus-host disease

  In people aged 12 and up with chronic graft-versus-host disease, the study tests belumosudil to see if it works better than the doctor’s choice of best available therapy after prior treatments have failed.

  Recruiting at 3 sites Phase 3 Sanofi · Amsterdam and 2 other locations · NCT07771439

• Mindfulness program to help with symptoms in chronic graft-versus-host disease

  A mindfulness-based program is being tested to see if it can reduce patient-reported symptoms for adults with chronic graft-versus-host disease after a stem cell transplant.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07733141

• Madecassoside tablets plus standard therapy for sclered scl-cGVHD after allo-HSCT

  This study tests whether adding madecassoside tablets to standard therapy can help people with scleral chronic graft-versus-host disease after stem cell transplant.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07606703

• Post-transplant dental cleaning to prevent chronic graft-versus-host disease

  This will try a dental cleaning about 28 days after an allogeneic stem cell transplant to see if it lowers the chance of chronic graft-versus-host disease in adult transplant recipients.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT07535008

• Adrixetinib (Q702) for adults with active chronic graft-versus-host disease.

  This trial will test whether the oral drug Adrixetinib (Q702) is safe and helps adults with moderate or severe active chronic graft-versus-host disease who have not responded to standard treatments.

  Recruiting at 8 sites Phase 1 Qurient Co., Ltd. · Barcelona and 7 other locations · NCT07138196

• How whole versus crushed belumosudil tablets behave in people with chronic GVHD

  This will test whether taking belumosudil as whole tablets or crushed tablets suspended in water changes how the drug is absorbed in adults with chronic graft-versus-host disease.

  Recruiting Phase 1 M.D. Anderson Cancer Center · Houston, Texas · NCT07127926

• Axatilimab versus best available therapy for children with chronic graft-versus-host disease after two or more prior treatments

  This trial will test axatilimab against the best available treatments in children aged 2–17 whose chronic graft-versus-host disease has not responded to at least two prior systemic therapies.

  Recruiting at 34 sites Phase 2 Incyte Corporation · Duarte, California and 40 other locations · NCT07124078

• Belumosudil treatment for children with chronic graft-versus-host disease (schoolROCK)

  This trial will test whether the oral drug belumosudil helps children ages 1 to under 18 with moderate-to-severe chronic graft-versus-host disease that has not improved after at least two prior systemic treatments.

  Recruiting at 35 sites Phase 2 Sanofi · Los Angeles, California and 34 other locations · NCT07116031

• Gecacitinib treatment for moderate-to-severe chronic GVHD after two or more prior therapies

  This trial will try oral gecacitinib in adults with moderate-to-severe chronic GVHD who have had at least two prior systemic treatments to see if it is safe and helps control disease.

  Recruiting Phase 1/2 Peking University First Hospital · Beijing · NCT07012304

• Axatilimab to treat skin thickening (sclerosis) from chronic graft‑versus‑host disease

  This trial tests whether axatilimab can improve or stop worsening skin thickening (sclerosis) in adults with chronic graft‑versus‑host disease after a donor stem cell transplant.

  Recruiting at 2 sites Phase 2 Fred Hutchinson Cancer Center · Tampa, Florida and 2 other locations · NCT07011810

• Combination treatment for chronic Graft-versus-Host Disease

  This study is testing a new combination treatment with Axatilimab and light therapy to see if it helps people with chronic Graft-versus-Host Disease who haven't responded well to other treatments.

  Recruiting at 3 sites Phase 2 University of Miami · San Francisco, California and 2 other locations · NCT06663722

• Evaluating axatilimab and corticosteroids for treating chronic graft-versus-host disease

  This study is testing if adding a new drug called axatilimab to standard steroids can help people aged 12 and older who have recently developed moderate to severe chronic graft-versus-host disease feel better.

  Recruiting at 131 sites Phase 3 Incyte Corporation · Birmingham, Alabama and 130 other locations · NCT06585774

• Treatment of chronic graft-versus-host disease with TQ05105 tablets

  This study is testing if TQ05105 tablets can help improve symptoms and overall health in adults with moderate-to-severe chronic graft-versus-host disease after a stem cell transplant.

  Recruiting Phase 2 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Hefei, Anhui and 11 other locations · NCT06300320

• Understanding the immune response in chronic Graft Versus Host Disease after stem cell transplantation

  This study is trying to learn more about the immune system's response in people with chronic Graft Versus Host Disease after a stem cell transplant to find better ways to treat it.

  Recruiting University Hospital, Bordeaux · Pessac · NCT06247150

• Ruxolitinib plus fostamatinib for adults with steroid-refractory chronic graft-versus-host disease

  This tests whether adding fostamatinib to ruxolitinib helps adults with chronic GvHD who haven't responded well to steroids.

  Recruiting Phase 1 Duke University · Durham, North Carolina · NCT06233110

• Belumosudil treatment for chronic graft versus host disease

  This study is testing if a new drug called belumosudil can help people with chronic graft versus host disease feel better compared to a placebo.

  Recruiting at 5 sites Phase 2 Fred Hutchinson Cancer Center · Duarte, California and 4 other locations · NCT05996627

• Using belumosudil to prevent or treat bronchiolitis obliterans in stem cell transplant patients

  This study is testing if a new medication called belumosudil can help prevent or treat bronchiolitis obliterans in patients who have recently had a stem cell transplant.

  Recruiting at 4 sites Phase 2 Dana-Farber Cancer Institute · Stanford, California and 5 other locations · NCT05922761

• Axatilimab at Three Doses for Chronic GVHD

  This study tests three dose levels of axatilimab in people 2 years and older whose chronic graft-versus-host disease has not responded to at least two prior treatments.

  Recruiting at 13 sites Phase 2 Syndax Pharmaceuticals · Birmingham, Alabama and 120 other locations · NCT04710576

• Hydrogen treatment for chronic graft-versus-host disease

  This study is testing if hydrogen treatment can help people with chronic graft-versus-host disease who haven't responded well to steroid medications.

  Recruiting Phase 2 Navy General Hospital, Beijing · Beijing, Beijing Municipality · NCT02918188

Related topics

Quick answers

How many Chronic Graft Versus Host Disease clinical trials are recruiting right now?

19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 23 countries. The most sites are in United States (12 trials), Spain (6 trials), China (5 trials), France (4 trials), Germany (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 10, Phase 1: 3, Phase 3: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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