Condition

Decision Making clinical trials and research

• 16Clinical trials
• 388NIH research projects
• 5Countries

Newest Decision Making clinical trials

All recruiting trials (16)

• How vaccine-related inflammation may affect how doctors make treatment decisions

  This study tests whether a mild inflammatory state from a flu shot changes decision-making in emergency and internal medicine clinicians.

  Recruiting at 3 sites Phase 2 University of Arkansas, Fayetteville · Fayetteville, Arkansas and 2 other locations · NCT07842367

• Testing Alcohol Health Warning Labels for US Adults

  A randomized online study will test different warning statements about alcohol and breast cancer risk among adult US women who drink or are young non-drinkers to see which warnings are most convincing.

  Recruiting University of Oklahoma · Oklahoma City, Oklahoma · NCT07812545

• Benchmarking AI language models against tumor boards for oncology treatment decisions

  This project tests whether frontier AI language models can match the treatment recommendations of multidisciplinary tumor boards for common cancers using standardized synthetic cases.

  Recruiting Assistance Publique - Hôpitaux de Paris · Boulogne-Billancourt and 4 other locations · NCT07739121

• Heart rate variability feedback to help practitioners make better patient decisions

  This study tests whether giving healthcare workers HRV feedback during care improves how quickly and safely they respond to ventilator events and bedside needs.

  Recruiting Papworth Hospital NHS Foundation Trust · Cambridge, Cambridgeshire · NCT07709364

• Testing warning labels on cannabis packaging to see what design helps people notice risks

  Researchers are testing different cannabis warning labels to see which designs make people notice health risks and think about their use more carefully.

  Recruiting University of Oklahoma · Oklahoma City, Oklahoma · NCT07701304

• Support for Just-In-Time Consent for Prenatal Screening

  This study tests a short set of information cards delivered on a phone to help pregnant people decide about prenatal screening.

  Recruiting at 3 sites Case Western Reserve University · San Francisco, California and 2 other locations · NCT07557303

• BRIDGE: A program to help families make decisions for critically ill kids

  This intervention tests whether the BRIDGE program helps parents of seriously ill young children feel more prepared to make decisions and less regret about those choices.

  Recruiting Duke University · San Francisco, California and 2 other locations · NCT07390773

• How the brain simulates future moves during multi-step planning

  We will test whether healthy adults mentally simulate promising future move sequences while planning in a Four-in-a-Row game using brain recordings and eye tracking.

  Recruiting New York University · New York, New York · NCT07293637

• Initial testing of an educational approach to genetic services for families at risk of Lynch syndrome

  This pilot study tests whether an information letter alone or with a booklet helps at-risk relatives decide about pursuing genetic services for Lynch syndrome.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT07106359

• Improving substance use services in Oregon through data-driven decision-making

  This study is testing a new way to help Oregon's service providers and health officials use data better to improve substance use services and reduce overdoses.

  Recruiting Chestnut Health Systems · Eugene, Oregon · NCT06852170

• Improving medication prescribing for older nursing home residents

  This study tests if training healthcare workers to better manage medications can help older nursing home residents with serious illnesses receive care that matches their comfort and quality of life goals.

  Recruiting at 3 sites Amsterdam UMC, location VUmc · Apeldoorn, Gelderland and 6 other locations · NCT06731361

• Using telehealth to improve lung cancer screening decision-making

  This study tests if using telehealth can help patients make better decisions about lung cancer screening and ensure everyone has equal access to this important care.

  Recruiting Abramson Cancer Center at Penn Medicine · Philadelphia, Pennsylvania · NCT06638554

• Understanding how craving affects decision-making in opioid use disorder

  This study is testing how cravings for opioids affect the choices people with opioid use disorder make when deciding what to buy, using brain scans to see what's happening in their minds during the process.

  Recruiting Rutgers, The State University of New Jersey · Piscataway, New Jersey · NCT06440577

• Testing a decision support tool for improving child welfare interventions

  This study is testing a new online tool to help state decision-makers improve their choices in child welfare programs aimed at preventing child abuse and neglect.

  Recruiting Chestnut Health Systems · Eugene, Oregon · NCT06375551

• Improving math skills in children with learning disabilities

  This study tests a new way to help children with learning disabilities improve their math skills by using different methods to see what works best for them.

  Recruiting Stanford University · Palo Alto, California · NCT05201534

• Combining brain stimulation and cognitive training to improve decision-making and impulse control

  This study is testing if combining brain stimulation with cognitive training can help young adults make better decisions and control their impulses.

  Recruiting Queen's University · Kingston, Ontario · NCT03886025

NIH-funded research (newest 40 of 388)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding how octopuses integrate sensory information and make decisions

  This study is exploring how octopuses use their arms to grip things by looking closely at their nervous system and movements, which could help us understand their amazing abilities better.

  NIH research Michigan State University · East Lansing, United States · NIH-9949982

• NoviGuide for Newborn Care in Pakistan

  A small NIH grant to test a pocket-sized decision support tool for nurses and doctors to improve newborn care in Pakistan.

  NIH research Aga Khan University (Pakistan) · Karachi, Pakistan · NIH-11624823

• Understanding how aging and Alzheimer’s affect how people make tough choices

  This NIH grant studies how aging and Alzheimer’s risk change how people decide between immediate and delayed rewards and risky options, with the goal of helping older adults stay financially and healthwise safer.

  NIH research University of Florida · Gainesville, United States · NIH-11620311

• Shared decision-making to prevent cancer in South Africa

  A multi-level, school-based program in South Africa helps families, teachers, and health workers make informed choices to prevent cervical and related cancers, especially where HIV is common.

  NIH research Yale University · New Haven, United States · NIH-11603112

• Improving contraception decisions for women with substance use disorders after childbirth

  A patient-centered decision tool called MyPath aims to help postpartum women with substance use disorders choose and keep effective contraception after giving birth.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11601588

• Alcohol use and suicidal thoughts: how decision-making affects risk

  This project looks at how acute alcohol use and people’s decision-making patterns relate to suicidal thoughts and behaviors in adults.

  NIH research University of Kentucky · Lexington, United States · NIH-11592176

• STOP HIV care in people involved with the criminal legal system

  A multi-year program to help people who are involved with the criminal legal system access PrEP, ART, and substance use treatment in ways that fit their needs.

  NIH research Yale University · New Haven, United States · NIH-11550838

• Ecologically-realistic perceptual decision making in brain injury

  Researchers are testing how real-life visual decisions form from brain signals in people with acquired brain injury, using computer models and naturalistic tasks.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11538871

• Efficient control of brain signals to improve perceptual decisions

  This project tests whether people can reduce neural and behavioral noise during quick, uncertain perceptual decisions by using motivated control of sensory processing.

  NIH research Harvard Medical School · Boston, United States · NIH-11538108

• Multi-level shared decision-making to prevent cancer in South Africa

  A study from Yale will test a community-friendly, classroom- and family-centered program to help prevent cervical and other cancers in South Africa by guiding parents, teachers, and healthcare workers to make informed choices together.

  NIH research Yale University · New Haven, United States · NIH-11520642

• How brain connections guide visual choices in ADHD

  A research study aims to understand how specific brain pathways help people with ADHD make visual decisions, using non-invasive methods in primates.

  NIH research Methodist Hospital Research Institute · Houston, United States · NIH-11520034

• Using blood tests and single-cell epigenetics to detect aggressive changes in prostate cancer

  Researchers will use blood-based liquid biopsies and single-cell epigenetic tests to look for early signs that prostate cancer is becoming resistant to hormone treatments in men with advanced disease.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11507481

• Better tracking of what kills children under five in low-income countries

  This project improves how we measure what causes deaths at different ages under five to help children and health programs in low-income countries.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11496469

• DECIDE-AF: a shared decision tool in your health portal to help prevent strokes in atrial fibrillation

  A patient-friendly tool in your electronic health record helps you and your doctor choose the right way to prevent strokes if you have atrial fibrillation.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11450366

• Mutual influence of alcohol craving and decision-making

  A program at Yale will study how craving for alcohol and everyday decisions affect each other, with the goal of better understanding and helping people who struggle with heavy drinking.

  NIH research Yale University · New Haven, United States · NIH-11448771

• Real-world safety and decision help for new Alzheimer's treatments

  This grant looks at how monoclonal antibody drugs for Alzheimer’s affect people in real life and creates a practical decision aid for patients and families.

  NIH research Hebrew Rehabilitation Center for Aged · Boston, United States · NIH-11448523

• Advancing Shared Decision Making for Stroke Prevention in Atrial Fibrillation

  Aims to combine data from three big trials to understand how decision aids help people with atrial fibrillation choose anticoagulation to prevent stroke, in a patient-centered way.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11445391

• Shared Decision Making for Depression Care in Primary Care

  A practical program to help adults with depression in primary care discuss treatment options with their doctors more clearly and together.

  NIH research Temple Univ of the Commonwealth · Philadelphia, United States · NIH-11431828

• Personalized breast cancer care with COMPASS: a patient-friendly decision aid integrated with your medical records

  A research project aims to help breast cancer patients make informed treatment choices through a computerized decision-support tool linked to their health records.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11429471

• PSA Screening: Understanding Benefits and Risks for Black Men

  This grant studies how PSA screening affects Black men to help tailor guidelines and decision-making.

  NIH research Veterans Medical Research Fdn/san Diego · San Diego, United States · NIH-11428699

• How loud noise can change the brain's sound decisions

  This project looks at how loud noise-related hearing loss may affect how people process sounds and make quick decisions about what they hear.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11425431

• Integrating breast cancer and heart disease risk to understand chemoprevention decisions for high-risk women

  This project explores how women at high risk for breast cancer decide whether to take preventive medicines, while also considering their heart health.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11421824

• Salpingectomy to Cut Ovarian Cancer Risk: Improving Use and Informed Choices

  A project at Columbia University aims to help women reduce ovarian cancer risk by removing the fallopian tubes during other surgeries, while keeping the ovaries intact, and to make sure patients and providers understand the benefits and options.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11421121

• Understanding how doctor habits and workloads affect care for people with Alzheimer's and related dementias

  This grant looks at how doctors decide on care for people with ADRD in the emergency department and how provider workload and team dynamics influence outcomes.

  NIH research National Bureau of Economic Research · Cambridge, United States · NIH-11420407

• HEARTSPOT: A smart aid for emergency doctors helping people with Alzheimer's and related dementias when heart issues arise

  A team is testing a smart AI tool that helps ED clinicians make better treatment choices for people with ADRD who have acute heart problems.

  NIH research National Bureau of Economic Research · Cambridge, United States · NIH-11420399

• Understanding and improving care for people living with Alzheimer's disease and related dementias

  A program of research to help doctors, caregivers, and patients with Alzheimer’s disease and related dementias make better health choices and get better care.

  NIH research National Bureau of Economic Research · Cambridge, United States · NIH-11420385

• Personalized Methadone Care: Shared Decisions in Opioid Treatment Programs

  A project to help people with opioid use disorder get methadone treatment that fits their preferences by supporting clinicians with tools to share decisions and tailor dosing.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11419183

• Fronto-thalamic circuits and decision making under uncertainty in children’s brain health

  A study with children’s brain health in mind will explore how the frontal cortex and thalamus work together when choices are uncertain, to better understand conditions like schizophrenia.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11417961

• Risk-Benefit Decisions for Metoidioplasty and Phalloplasty

  A patient-friendly project is testing a web-based decision aid to help people considering metoidioplasty or phalloplasty understand options, risks, and outcomes to make informed choices.

  NIH research Dartmouth-Hitchcock Clinic · Lebanon, United States · NIH-11417425

• Data-driven decisions to improve substance-use services and prevent overdoses

  A project to create and share practical, easy-to-use data for people who run substance-use services and related agencies in Oregon.

  NIH research Chestnut Health Systems, INC. · Bloomington, United States · NIH-11415880

• Alcohol, arousal, and safer sex for men who have sex with men (MSM)

  A study with adult MSM tests a brief intervention to help reduce condomless sex when alcohol and arousal are high.

  NIH research Boston University (Charles River Campus) · Boston, United States · NIH-11413639

• How we make tough choices in the brain

  This project studies how the brain weighs different attributes (like costs and benefits) when people make complex decisions.

  NIH research New York University · New York, United States · NIH-11412722

• Shared decision-making tool to improve firearm storage in families with children

  A patient-friendly trial tests a web-based tool that helps families decide together how to store firearms safely when children are in the home.

  NIH research Seattle Children's Hospital · Seattle, United States · NIH-11408777

• Guiding delivery decisions to improve outcomes for high-risk pregnancies with high blood pressure

  A physician-scientist at NYU is studying when to induce labor versus performing a cesarean in pregnant people with high blood pressure to reduce serious pregnancy-related problems.

  NIH research New York University School of Medicine · New York, United States · NIH-11408618

• Optimizing opioid treatment for people leaving prison

  This project tests simple screening and a small diagnostic checklist to help identify opioid use disorder in prisoners and link them to medication for opioid use disorder (MOUD) when they’re released.

  NIH research University of Washington · Seattle, United States · NIH-11406216

• Gut bacteria and how they influence alcohol seeking and decisions

  This project looks at whether the bacteria living in the gut affect how people or animals seek alcohol and make decisions about drinking.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11404984

• Odor trail tracking explains how senses guide decisions and brain circuits

  Scientists are studying how mice actively smell and move to track a odor trail, revealing how the brain combines sense and action to guide continuous choices.

  NIH research Harvard University · Cambridge, United States · NIH-11404027

• Shared decision support to prevent cancer in South African youth

  This project offers school-based education and shared decision tools to help parents, teachers, and adolescents in Gauteng, South Africa, prevent HPV-related cancers.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11403599

• Understanding how affect and motivation influence heavy drinking decisions

  A researcher is studying how feelings influence when and why people choose to drink heavily, with the goal of helping people who struggle with alcohol use.

  NIH research University of Washington · Seattle, United States · NIH-11402830

• Improving how patients choose their hemodialysis access

  A patient-friendly project to help people with kidney failure better understand and decide between AV fistula, graft, or catheter for hemodialysis.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11400532

Related topics

Quick answers

How many Decision Making clinical trials are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (12 trials), France (1 trial), United Kingdom (1 trial), Netherlands (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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