Improving medication prescribing for older nursing home residents

Improving Medication Prescription in the contExt of Advance Care Planning for paTients Receiving Long Term nUrSing Home Care

Not applicable Interventional Amsterdam UMC, location VUmc · NCT06731361

This study tests if training healthcare workers to better manage medications can help older nursing home residents with serious illnesses receive care that matches their comfort and quality of life goals.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment450 (estimated)
Ages65 Years and up
SexAll
SponsorAmsterdam UMC, location VUmc Academic / other
Locations7 sites (Apeldoorn, Gelderland and 6 other locations)
Trial IDNCT06731361 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of training healthcare professionals on medication assessments for nursing home residents with limited life expectancy. It employs a cluster randomized controlled trial design, involving six nursing home organizations and aiming to include 450 patients aged 65 and older. The intervention focuses on tailoring medication use to align with the palliative treatment goals of these residents. The study will last for 15 months, starting in September.

Who should consider this trial

Good fit: Ideal candidates are nursing home patients aged 65 and older with a life expectancy of less than 1.5 to 2 years.

Not a fit: Patients with a life expectancy of less than 4 weeks or those expected to live significantly longer than 1.5 to 2 years may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more appropriate medication use and improved quality of life for nursing home residents nearing the end of life.

How similar studies have performed: Other studies have shown success in improving medication management in similar populations, indicating that this approach has potential.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Nursing home patients:

* Age 65years and above
* Living at long term care wards in nursing homes
* Living at a long term care ward for at least 4 weeks before start of the study

Exclusion Criteria:

* Temporary nursing home patients (i.e. geriatric rehabilitation or end-of-life/hospice care)
* Life expectancy \< 4 weeks
* Life expectancy clearly \> 1.5 - 2 years (i.e. patients with Huntingtons disease)

Where this trial is running

Apeldoorn, Gelderland and 6 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Nursing Home ResidentsOlder PeoplePrescribingAdvance Care PlanningMedication ReviewsDecision MakingPrescribing Practiceslimited life expectancy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.