Clinical trial Recruiting at 3 sites Interventional Ages 65 and up

Improving medication prescribing for older nursing home residents

Official title: Improving Medication Prescription in the contExt of Advance Care Planning for paTients Receiving Long Term nUrSing Home Care

Run by Amsterdam UMC, location VUmc · NCT06731361 · Data updated 2026-11-12

This study tests if training healthcare workers to better manage medications can help older nursing home residents with serious illnesses receive care that matches their comfort and quality of life goals.

Quick facts

Study typeInterventional
Ages65 Years and up
SexAll
Enrollment450 (estimated)
SponsorAmsterdam UMC, location VUmc
Academic / other
Locations7 sites (Apeldoorn, Gelderland and 6 other locations)
StatusRecruiting
StartedSeptember 10, 2024
Main results expectedDecember 1, 2025
Study endsDecember 1, 2025
Registry record updatedDecember 12, 2024
Trial IDNCT06731361 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are nursing home patients aged 65 and older with a life expectancy of less than 1.5 to 2 years.

Probably not a fit

Patients with a life expectancy of less than 4 weeks or those expected to live significantly longer than 1.5 to 2 years may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of training healthcare professionals on medication assessments for nursing home residents with limited life expectancy. It employs a cluster randomized controlled trial design, involving six nursing home organizations and aiming to include 450 patients aged 65 and older. The intervention focuses on tailoring medication use to align with the palliative treatment goals of these residents. The study will last for 15 months, starting in September.

Why it matters

Potential benefit: If successful, this study could lead to more appropriate medication use and improved quality of life for nursing home residents nearing the end of life.

How similar studies have gone: Other studies have shown success in improving medication management in similar populations, indicating that this approach has potential.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Nursing home patients:

* Age 65years and above
* Living at long term care wards in nursing homes
* Living at a long term care ward for at least 4 weeks before start of the study

Exclusion Criteria:

* Temporary nursing home patients (i.e. geriatric rehabilitation or end-of-life/hospice care)
* Life expectancy \< 4 weeks
* Life expectancy clearly \> 1.5 - 2 years (i.e. patients with Huntingtons disease)

Where it's running

  • Cordaan, location Nieuw Vredenburgh
    Amsterdam, North Holland, Netherlands
    Recruiting
  • AxionContinu, location Isselwaerde and de Schutse
    IJsselstein, Utrecht, Netherlands
    Recruiting
  • Zorgspectrum, location de Plataan
    Vianen, Utrecht, Netherlands
    Recruiting
  • Zorggroep Apeldoorn, location Randerode, De Hofstede and De Windkanter
    Apeldoorn, Gelderland, Netherlands
    Active not recruiting
  • Zorggroep Noordwest-Veluwe, locaties Weideheem en de Arcade
    Harderwijk, Gelderland, Netherlands
    Active not recruiting
  • Amaris, Location Alporti and Rubina
    Hilversum, North Holland, Netherlands
    Active not recruiting
Show 1 more location
  • Dignis, location de Veldspaat
    Groningen, Netherlands
    Active not recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.