NIH-funded research R01 grant

Mutual influence of alcohol craving and decision-making

Official title: Neurocomputational and ecological assessments of the mutual influence between alcohol craving and decision-making

Funded at Yale University · NIH-11448771 · Data updated 2026-11-12

A program at Yale will study how craving for alcohol and everyday decisions affect each other, with the goal of better understanding and helping people who struggle with heavy drinking.

More Decision Making research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startSeptember 1, 2026
Project endApril 30, 2031
Funding year2026
Award (this year)$671,854
NIH project number1R01AA032545-01A1
Project IDNIH-11448771 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are adults with alcohol use disorders or heavy drinking patterns who can participate in lab tasks and real-world monitoring.

Less likely to help

Individuals without heavy drinking concerns or those unable to complete longitudinal monitoring may not benefit.

What this research studies

This project explores how craving and decision-making interact in people who binge or heavy drink. It uses neurocomputational methods to link brain activity in reward networks to real-world drinking behavior and craving signals. The study combines laboratory tasks with models that describe how cravings unfold over time and influence choices about drinking. By examining both lab-based measures and real-life dynamics, it aims to create a clearer picture of how cravings drive risky decisions. The findings could inform future interventions to reduce harmful drinking patterns.

Why it matters

Potential benefit: If successful, this work could lead to more effective strategies to curb craving-driven drinking and support healthier decision-making.

How similar studies have gone: Previous work has shown promising links between brain reward circuits and drinking behavior, though integrating real-world dynamics remains novel.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Gu, Xiaosi — Yale University
  • Study coordinator: Gu, Xiaosi

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.