Condition

Implementation Science clinical trials and research

• 21Clinical trials
• 189NIH research projects
• 6Countries

Newest Implementation Science clinical trials

All recruiting trials (21)

• Toolkits to help providers deliver Diabetes Coaching to adolescents with Type 1 diabetes

  This study tests whether groups of implementation tools can help pediatric diabetes and psychology teams at a Delaware hospital deliver Diabetes Coaching to more families.

  Recruiting Nemours Children's Clinic · Wilmington, Delaware · NCT07766811

• Healthy Options At Pantries prompts healthier online pantry choices

  A digital nudge called HOAP is tested in online food pantries to see if it helps shoppers pick healthier items.

  Recruiting Northwestern University · Chicago, Illinois · NCT07729436

• Choose to Move Replacement Ready for OA patients waiting for hip or knee replacement

  This program tests a tailored, online version of a 3-month activity and social-connection plan for older adults with hip or knee osteoarthritis who are waiting for joint replacement surgery to see if it improves physical activity and health while they wait.

  Recruiting University of British Columbia · Vancouver, British Columbia · NCT07696650

• Seated Tai Chi/Qigong for Women with Mobility Impairments delivered at home

  A remotely delivered seated Tai Chi/Qigong program is being tested to see if it improves cardiometabolic health, stress, sleep, and well-being in women with mobility impairments.

  Recruiting Arizona State University · Phoenix, Arizona · NCT07675681

• Corrie Lipids program to help lower high LDL cholesterol

  This program tests whether a smartphone app combined with clinician education and coaching can help adults with uncontrolled LDL-C and high cardiovascular risk reach their cholesterol goals.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07478887

• CommunityRx-Dpeer: peer-led support to help dementia caregivers connect with community resources

  This program tests a peer navigator model to help dementia caregivers access personalized community resources and ongoing support over 12 months.

  Recruiting University of Chicago · Chicago, Illinois · NCT07346183

• Parents Helping Parents for Youth Vaping Cessation

  This project tests whether a parent-supported program can help teens quit vaping by pairing trained parent coaches with families.

  Recruiting University of Nebraska · Omaha, Nebraska · NCT07207850

• Using a matching tool to help nurses choose the best IV device for children

  We will test whether the CFIR-ERIC matching tool helps pediatric nurses pick the right venous access device and make fewer selection mistakes.

  Recruiting Children's Hospital of Fudan University · Shanghai · NCT07184489

• Cardiac point-of-care ultrasound training pathway for emergency advanced practice providers

  This project will test a simulation-based and just-in-time training program to teach emergency department nurse practitioners and physician assistants to perform focused cardiac POCUS.

  Recruiting Duke University · Durham, North Carolina · NCT07159269

• Choose to Move Replacement Ready for people waiting for hip or knee replacement

  This project will test whether the Choose to Move Replacement Ready program helps older adults on hip or knee replacement waitlists increase physical activity, improve mobility, and support psychosocial health.

  Recruiting University of British Columbia · Vancouver, British Columbia · NCT07069179

• Low-barrier hepatitis C treatment program in jail

  This project tests whether a simplified 12-week Epclusa treatment with community health worker support helps adults in jail with active hepatitis C start and finish therapy.

  Recruiting Phase 4 Lifespan · Cranston, Rhode Island · NCT06953479

• A youth-led program to help young people with HIV move from pediatric to adult care

  This project will test whether a youth-led, data-driven approach helps clinics deliver a transition package that improves care for young people living with HIV (ages 10–24) in Kenya.

  Recruiting at 24 sites University of Washington · Awendo and 24 other locations · NCT06924073

• Improving substance use services in Oregon through data-driven decision-making

  This study is testing a new way to help Oregon's service providers and health officials use data better to improve substance use services and reduce overdoses.

  Recruiting Chestnut Health Systems · Eugene, Oregon · NCT06852170

• Home-based cervical cancer self-sampling with education for women living with HIV in Ghana

  This study tests a home-based HPV self-sampling approach plus a 3R communication plan to help women with HIV in Ghana screen for cervical cancer.

  Recruiting Baylor University · Cape Coast, Central Region · NCT06800664

• Testing a decision support tool for improving child welfare interventions

  This study is testing a new online tool to help state decision-makers improve their choices in child welfare programs aimed at preventing child abuse and neglect.

  Recruiting Chestnut Health Systems · Eugene, Oregon · NCT06375551

• New consent process for using newborn screening samples in research

  This study is testing a new online consent process to see if it helps new mothers better understand and accept how their babies' newborn screening samples can be used for research.

  Recruiting at 2 sites University of Utah · Salt Lake City, Utah and 1 other locations · NCT06192511

• Improving ICU care through behavioral strategies

  This study is testing two strategies to help ICU staff use better practices for caring for critically ill adults, especially those facing health challenges, to see if it can improve patient recovery and reduce complications.

  Recruiting at 3 sites University of Nebraska · Iowa City, Iowa and 2 other locations · NCT06184945

• Pilot program to offer comprehensive geriatric assessments before major surgery.

  This pilot will try a system-level package to see if more people aged 80 and older can get a full comprehensive geriatric assessment (CGA) before elective major surgery.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06184724

• Improving ADHD treatment through team-based school interventions

  This study is testing a new team-based approach to improve a school program for children with ADHD to see if it helps them do better in school.

  Recruiting University of California, San Diego · San Diego, California · NCT06180681

• Improving pediatric injury care in Tanzania

  This study is testing a new program to improve how injured children are cared for in Tanzania by making sure they get the right help faster.

  Recruiting University of Utah · Moshi · NCT06075108

• Comparing two approaches to prevent delirium in hospitalized older adults

  This study tests whether involving family members in care can help prevent delirium in older adults during hospital stays better than the standard Hospital Elder Life Program alone.

  Recruiting at 7 sites University of Michigan · Orange, California and 6 other locations · NCT05929703

NIH-funded research (newest 40 of 189)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Improving colorectal cancer screening and follow-up care.

  This study is working to help more people get screened for colorectal cancer and receive the follow-up care they need, especially those who haven't been screened much before, so that everyone can have better access to important health checks and improve their overall health.

  NIH research Research Triangle Institute · Research Triangle Park, United States · NIH-9627071

• Making HIV prevention and care easier for Ugandan youth

  A Ugandan study is testing ways to help adolescents and young adults (15–24) prevent HIV and stay healthy, using long-acting PrEP and youth-friendly services.

  NIH research Mu-Jhu Care · Kampala, Uganda · NIH-11644400

• Innovative HIV Prevention and Care Interventions for Adolescents and Young Adults in Uganda

  A Ugandan research team is testing practical, youth-focused strategies to help 15-24 year-olds using HIV prevention or treatment services stay healthy and engaged in care.

  NIH research Mu-Jhu Care · Kampala, Uganda · NIH-11644068

• How Poverty and the Environment Affect Heart Disease in Haiti and Beyond

  This grant studies how poverty-related factors like food insecurity, stress, and pollution contribute to heart disease and aims to follow a large group of adults to better understand and prevent the disease.

  NIH research Washington University · Saint Louis, United States · NIH-11630192

• Resilient HIV Implementation for LGBTQ Youth in Africa and Beyond

  A program to help young people ages 15–24 who are at risk for or living with HIV, especially sexual and gender minority youths, access better HIV prevention and care through real-world health practice improvements.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11628851

• Regional hub to speed up ending HIV with practical science

  A regional collaboration will translate proven HIV interventions into real-world practice to reduce new infections across priority areas.

  NIH research University of Washington · Seattle, United States · NIH-11609319

• Hopkins Hub: Accelerating HIV Implementation Science to End the Epidemic

  A regional hub from Johns Hopkins aims to strengthen HIV implementation research and collaborations to help end the HIV epidemic.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11609182

• HIV Implementation Science Coordination Initiative

  A national effort to speed up and spread through communities proven HIV interventions so people who are most affected can get better care and prevention.

  NIH research Northwestern University · Chicago, United States · NIH-11601580

• UAB HIV Implementation Science Hub: Building Real-World Ways to End the HIV Epidemic

  A regional hub in the Deep South is helping researchers and communities implement proven HIV strategies to reduce new infections and improve care.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11591253

• Connecting Black MSM with HIV Care: Modeling and Real-World Implementation

  A patient-facing project using computer models to figure out better ways to link Black men who have sex with men to HIV care and keep them engaged.

  NIH research University of Chicago · Chicago, United States · NIH-11566339

• LISTOS for Cancer Control: Using implementation science to spread proven cancer care

  A center-led effort to speed up the use of proven cancer prevention and screening strategies in diverse health systems, especially in underserved communities.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11535794

• LISTOS for Cancer Control: Faster, Better Cancer Care Through Smarter Implementation

  A national center will help health systems adopt and sustain proven cancer control programs to improve breast and colorectal cancer screening and diagnostics, especially in underserved communities.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11535793

• Understanding how poverty and environment influence heart disease and health in adults

  A study follows adults in a long-term cohort to understand how poverty, stress, diet, and pollution affect heart and blood conditions.

  NIH research Washington University · Saint Louis, United States · NIH-11535757

• Enhanced breast and cervical cancer screening in Kenya through implementation science and training

  A multi-institution effort to boost breast and cervical cancer screening, follow-up, and treatment in Kenya using hands-on implementation science and training.

  NIH research Emory University · Atlanta, United States · NIH-11535279

• US-Nigerian Center to Speed Up Cancer Prevention Through Smart Implementation

  A US-Nigerian partnership plans to spread HPV and hepatitis B vaccines to prevent cancer using community-friendly, participatory approaches.

  NIH research Washington University · Saint Louis, United States · NIH-11535268

• From Genes to Community: Understanding Birth Clefts and Supporting Families

  A multi-omics study from bench to community to find genetic risk factors for cleft lip/palate and use those findings to support families and caregivers in Africa.

  NIH research University of Iowa · Iowa City, United States · NIH-11533000

• Resilient HIV Implementation for LGBTQ Youth in Africa and Beyond

  A patient-facing program aims to strengthen how HIV prevention and care are delivered to sexually and gender minority youths aged 15–24 who are at risk for or living with HIV.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11529272

• CARE-AI: Community-led ethical AI guidance for HIV care and research

  A community-driven project will create ethical recommendations for using artificial intelligence in HIV implementation science to help ending the HIV epidemic.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11482196

• Improving HIV Prevention and Care for Ugandan Adolescents and Young Adults

  A Uganda-based research effort aims to boost HIV prevention and care outcomes for 15-24 year-olds by testing practical, community-based strategies to increase PrEP use and viral suppression.

  NIH research Mu-Jhu Care · Kampala, Uganda · NIH-11478467

• Adolescent and Youth HIV Prevention and Care Improvements in Uganda

  A UG1 grant is testing ways to help Ugandan teens and young adults (ages 15-24) prevent HIV and stay healthy if they have HIV, using new long-acting PrEP and community care approaches.

  NIH research Mu-Jhu Care · Kampala, Uganda · NIH-11478466

• Malkia Klabu: safer, youth-friendly pharmacies to boost HIV prevention for AGYW in Tanzania

  A Tanzania-based project tests a youth-friendly pharmacy model to improve access to HIV prevention and sexual health services for adolescent girls and young women.

  NIH research Centre of Excellence in Health Monitoring and Evaluation · Morogoro, Tanzania U Rep · NIH-11478457

• HIV care options tailored to patients' needs

  This project compares different ways of delivering HIV care to help adults on treatment or using PrEP stay on treatment, keep the virus suppressed, or avoid infection.

  NIH research Duke University · Durham, United States · NIH-11474700

• Resilient HIV Implementation for LGBTQ Youth in Africa and globally

  A nationally/internationally coordinated program helps young people aged 15-24 who are at risk of or living with HIV, especially sexual and gender minorities, access better prevention and care through digital health and partnerships.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11474430

• Resilient HIV Implementation for HIV prevention and care in young sexual and gender minority youth

  A nationally coordinated program works with teens and young adults who are at risk for or living with HIV to speed up real-world solutions that prevent HIV and improve care for these groups.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11474429

• Resilient HIV Implementation for HIV Prevention and Care in LGBTQ Youth in Africa and beyond

  A patient-friendly program aims to improve HIV prevention and care for sexual and gender minority youths ages 15–24 who are at risk or living with HIV.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11474428

• Resilient HIV Implementation Science for LGBTQ Youths Now

  A nationwide program helps improve HIV prevention and care for young sexual and gender minority people (ages 15–24) by testing practical ways to put proven strategies into real-world use.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11474427

• Resilient HIV Implementation Center for LGBTQ Youth in Africa and Beyond

  A patient-facing program to speed up how HIV prevention and care reach 15-24 year-old sexual and gender minority youth, especially in Africa, by studying real-world ways to put proven practices into everyday care.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11474426

• Proyecto Tariki: Community-driven dengue prevention and response

  This project helps communities in Peru use neighborhood-led actions and a mobile platform to reduce mosquito breeding and dengue illness.

  NIH research Tulane University of Louisiana · New Orleans, United States · NIH-11462453

• Making depression care easier for cancer patients using digital tools

  A research project at Columbia University will test how to quickly connect cancer patients with depression care using digital health tools and real-world care pathways.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11423731

• Advancing health equity through community-led prevention in Atlanta

  A prevention research center in Atlanta is testing community-powered ways to reduce health disparities and improve access to prevention services for African American and minority communities.

  NIH research Morehouse School of Medicine · Atlanta, United States · NIH-11423356

• Making HIV care work better with high blood pressure prevention

  A program will test if integrating HIV care with blood pressure prevention and management can improve health outcomes and be cost-effective in African health systems.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11420765

• LISTOS for Cancer Control: Speeding Up Real-World Cancer Care Improvements

  A national center will speed up the adoption of proven cancer-control methods to improve breast and colorectal cancer screening and diagnostics, especially in underserved communities.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11419709

• Capacity Support for Implementation of HIV Research for LGBTQ+ Adolescents and Young Adults

  A capacity-building program helps youth with HIV in low- and middle-income countries by teaching practical, real-world ways to adapt and grow HIV research.

  NIH research Washington University · Saint Louis, United States · NIH-11418479

• Enhanced breast and cervical cancer screening in Kenya through implementation science and training

  A Breakthrough center project in Kenya aims to improve breast and cervical cancer screening, follow-up, and treatment through real-world implementation approaches and training.

  NIH research Emory University · Atlanta, United States · NIH-11416605

• US-Nigerian Center to Speed Cancer Prevention in the Community

  A US-Nigerian partnership is testing new, community-based ways to get HPV and HBV vaccines used more widely to prevent cancer.

  NIH research Washington University · Saint Louis, United States · NIH-11416435

• Ethics support for implementation research in humans

  This grant funds a dedicated ethics core to help researchers design and conduct implementation studies with people in a responsible, community-engaged way.

  NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11415936

• PrISM Core: a practical guide to getting implementation research done

  A core program helps researchers at KU Medical Center plan, design, and carry out real-world implementation studies to improve health care delivery.

  NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11415931

• Community Engagement and Outreach Core for Kansas Center for Implementation Science

  A patient-facing core helps researchers connect with patients, families, and communities to improve health work in rural Kansas.

  NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11415926

• Kansas Center for Implementation Science Administrative Core

  A national-level program at the University of Kansas Medical Center will build a structured hub to move proven health care ideas into everyday practice.

  NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11415922

• Kansas Center for Implementation Science: speeding up real-world care for Alzheimer’s

  Aimed at speeding up how doctors use proven Alzheimer’s care practices in everyday clinics to improve outcomes and reduce costs.

  NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11415921

Related topics

Quick answers

How many Implementation Science clinical trials are recruiting right now?

21, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (15 trials), Canada (2 trials), China (1 trial), Tanzania (1 trial), Ghana (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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