Clinical trial Recruiting at 1 site Interventional Ages 18 to 40

Combining brain stimulation and cognitive training to improve decision-making and impulse control

Official title: The Use of Combined Anodal Transcranial Direct Current Stimulation (tDCS) and Cognitive Training to Modulate Decision-making in Healthy People

Run by Queen's University · NCT03886025 · Data updated 2026-11-12

This study is testing if combining brain stimulation with cognitive training can help young adults make better decisions and control their impulses.

Quick facts

Study typeInterventional
Ages18 Years to 40 Years
SexAll
Enrollment60 (estimated)
SponsorQueen's University
Academic / other
Locations1 site (Kingston, Ontario)
StatusRecruiting
StartedSeptember 15, 2022
Main results expectedDecember 30, 2026
Study endsDecember 30, 2026
Registry record updatedAugust 8, 2025
Trial IDNCT03886025 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are healthy volunteers aged between 18 and 40.

Probably not a fit

Patients with epilepsy, neurological conditions, significant head injuries, or a history of substance misuse or major mental disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of combined anodal transcranial direct current stimulation (tDCS) and cognitive training on decision-making and impulse control in healthy volunteers aged 18 to 40. Participants will undergo either active or sham tDCS while performing the Iowa Gambling Task, which assesses decision-making under uncertainty. The study aims to determine if the combined intervention leads to more advantageous decisions and better impulse control compared to the sham treatment. Additionally, the research will explore whether these effects can be generalized to other cognitive tasks related to motor impulsivity.

Why it matters

Potential benefit: If successful, this approach could enhance decision-making and impulse control, potentially benefiting individuals with impulsivity-related issues.

How similar studies have gone: While there is limited research on the combined effects of tDCS and cognitive training, similar studies have shown promise in enhancing cognitive functions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Consenting volunteers aged between 18 and 40.

Exclusion Criteria:

* Individuals with epilepsy, other neurological conditions and history of significant head injury will be excluded.
* Individuals with a history of substance misuse, major mental disorder and those receiving psychotropic medication will be also excluded.

Where it's running

  • Queen's University
    Kingston, Ontario, Canada
    Recruiting

Study contacts

  • Principal investigator: Najat Khalifa, MD — Queen's University - Canada
  • Study coordinator: Najat Khalifa, MD, FRCPC
  • Email: nrk2@queensu.ca
  • Phone: 6135444900

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.