NIH-funded research R01 grant

Better tracking of what kills children under five in low-income countries

Official title: Improving Age- and Cause-Specific Under-Five Mortality Rates (ACSU5MR) by Systematically Accounting Measurement Errors to Inform Child Survival Decision Making in Low Income Countries

Funded at Johns Hopkins University · NIH-11496469 · Data updated 2026-11-12

This project improves how we measure what causes deaths at different ages under five to help children and health programs in low-income countries.

More Decision Making research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University
NIH-funded
Lab location1 site (Baltimore, United States)
Project startMay 11, 2023
Project endFebruary 29, 2028
Funding year2026
Award (this year)$82,983
NIH project number3R01HD107015-04S1
Project IDNIH-11496469 on NIH RePORTER

Who could benefit from this research

Could help

Children under five and their communities in low-income countries—especially those included in national surveys or verbal autopsy efforts—are the primary focus for data and potential local impact.

Less likely to help

Families in high-income settings or regions not represented in the analyzed data may not see direct benefits from this work.

What this research studies

If your child lives in a low-income country, this project aims to give clearer information about which illnesses or injuries cause deaths at different ages from birth to five years. Researchers will combine and re-analyze existing sources like surveys, death records, and verbal autopsies and use statistical methods to correct common measurement errors. The team will produce age- and cause-specific death estimates with more precision so health workers can match interventions to the ages and causes that matter most. Those results are meant to guide governments and aid groups on where to focus vaccines, treatments, and other programs.

Why it matters

Potential benefit: If successful, it could help target vaccines, treatments, and health programs more precisely to reduce child deaths.

How similar studies have gone: Previous work has produced broad under-five mortality estimates, but age-specific, cause-specific estimates that formally correct for measurement errors are relatively new and less tested.

Where this research is happening

  • Johns Hopkins University
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Liu, Li — Johns Hopkins University
  • Study coordinator: Liu, Li

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.