Clinical trial Recruiting at 1 site Interventional Ages 18 to 64

How the brain simulates future moves during multi-step planning

Official title: Identifying the Neural Correlates of Mental Simulation in Multi-Step Planning

Run by New York University · NCT07293637 · Data updated 2026-11-12

We will test whether healthy adults mentally simulate promising future move sequences while planning in a Four-in-a-Row game using brain recordings and eye tracking.

Quick facts

Study typeInterventional
Ages18 Years to 64 Years
SexAll
Enrollment50 (estimated)
SponsorNew York University
Academic / other
Locations1 site (New York, New York)
StatusRecruiting
StartedJuly 10, 2025
Main results expectedMarch 2026
Study endsDecember 2026
Registry record updatedJanuary 8, 2026
Trial IDNCT07293637 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Healthy adults without a history of neurological or psychiatric illness who can complete an online session and travel to New York University for an in-person brain-recording session on consecutive days.

Probably not a fit

People with a history of neurological or psychiatric illness or those unable to attend the in-person session in New York City are not eligible and are unlikely to receive direct benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research uses a two-session design to link behavior, computational models, and brain recordings. On day one, healthy adults complete an online training session playing Four-in-a-Row to provide behavioral data used to fit participant-specific planning models. On day two, participants attend an in-person neuroimaging session at NYU (MEG or fMRI) with simultaneous eye tracking while evaluating mid-game board positions within a fixed decision window. Analyses will use model-derived measures of simulated future states and values to determine where (fMRI) and when (MEG) the brain represents planning-related information.

Why it matters

Potential benefit: If successful, the findings could clarify how planning works in the brain and guide future treatments or diagnostics for disorders that impair decision-making.

How similar studies have gone: Prior fMRI and MEG studies using computational models have identified neural signatures of planning, but combining MEG and fMRI with eye tracking in a Four-in-a-Row tree-search task is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* N/A

Exclusion Criteria:

* History of neurological or psychiatric illness
* Vulnerable populations

Where it's running

  • New York University
    New York, New York, United States
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.