Improving math skills in children with learning disabilities

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the neurocognitive mechanisms that affect how children respond to interventions designed to enhance their numerical skills, particularly those with mathematical learning disabilities (MLD). Using a randomized controlled design, the study employs an integrated symbolic/non-symbolic intervention to improve the mapping between different representations of quantities. Researchers will develop computational models to explore individual differences in cognitive processes and brain plasticity that influence learning and retention of mathematical concepts. Performance will be assessed across various areas to understand the cognitive and neural mechanisms supporting numerical skill acquisition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Elementary school aged children starting from first grade (6-12 years old)
2. IQ: Participants with a Full Scale IQ \> 70 on the Wechsler Abbreviated Scle of Intelligence (WASI-II).
3. Identification of Mathematical Learning Disabilities: Scores below the 35th percentile percentile on symbolic number processing test in Numeracy Screener and two or more Wechsler Individual Achievement Test (WIAT-IV) math subtests
4. Identification of typically developing children: Scores at or above the 35th percentile percentile on symbolic number processing test in Numeracy Screener and all WIAT-IV math subtests
5. Normal or corrected-to-normal vision and no hearing impairments
6. Inclusion in MRI scan session: Right-handed

Exclusion Criteria:

1. History of neurological or psychiatric disorder (i.e., schizophrenia, psychosis, depression, or attention deficit hyperactivity disorder.)
2. History of trauma involving head injury
3. Consistent psychiatric medications
4. Exclusion from MRI scan session: No major contraindication for magnetic resonance imaging (MRI) - braces, metal implants, pacemakers, vascular stents, metallic ear tubes, consistent exposure to metal, claustrophobia)

Where it's running

• Stanford Cognitive and Systems Neuroscience Laboratory
  Palo Alto, California, United States Recruiting

Study contacts

• Study coordinator: Vinod Menon, PhD
• Email: menon@stanford.edu
• Phone: 16507363699

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.