Condition

Cerebrovascular Disease clinical trials and research

• 14Clinical trials
• 24NIH research projects
• 1New in 30 days
• 13Countries

Newest Cerebrovascular Disease clinical trials

All recruiting trials (14)

• Brain recovery after MCA reopening is studied with PET/MR

  This study tests how brain blood flow, metabolism, and networks change after reopening a non-acute atherosclerotic middle cerebral artery occlusion in adults receiving recanalization treatment.

  Recruiting Qianfoshan Hospital · Jinan, Shandong · NCT07927569

• NMR-based Risk Test and Digital Health Support for midlife adults in Eloisa

  This study tests whether an NMR metabolomics risk test can guide tailored digital health programs for midlife adults at risk of diabetes, heart disease, stroke, kidney disease, or fatty liver.

  Recruiting University of Eastern Finland · Savonlinna · NCT07820800

• Tegoprazan to prevent GI complications in ischemic stroke patients on antiplatelet therapy

  This trial tests whether tegoprazan can lower gastrointestinal complications in adults with ischemic stroke or TIA who are starting antiplatelet therapy.

  Recruiting at 24 sites Phase 3 Hanyang University · Busan, Busan and 23 other locations · NCT07687706

• Scalp nerve block with liposomal versus standard bupivacaine for post-craniotomy pain relief

  This trial will test whether adding liposomal bupivacaine to scalp nerve blocks gives longer, better pain relief than standard bupivacaine for adults after elective craniotomy.

  Recruiting Phase 4 Zhejiang University · Hangzhou, Zhejiang · NCT07049094

• Cohort study on imaging methods for cerebrovascular disease

  This study is testing different imaging methods to see how they can help understand and improve outcomes for people who have had a stroke.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT06925178

• Using QDSA technology to assess cerebrovascular diseases

  This study is trying to see if a new imaging technology can help doctors better understand and treat patients with cerebrovascular diseases by tracking their health over time.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT06902415

• Portable EEG to triage suspected stroke patients in ambulances

  This trial will test whether a portable dry‑electrode EEG headset (StrokePointer) can detect large vessel occlusion strokes in adults with suspected acute stroke so ambulance crews can take them directly to hospitals that perform thrombectomy.

  Recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Amsterdam, North Holland · NCT06871969

• National database for cerebrovascular disease

  This study is trying to find out what factors can predict how well people with cerebrovascular diseases will do by collecting data from their entire care journey.

  Recruiting Fondazione Don Carlo Gnocchi ETS · Florence, FI · NCT06859502

• Using magnetoencephalography to diagnose brain disorders in children

  This study is testing if a special brain imaging technique called magnetoencephalography can help doctors better diagnose brain disorders in children, like epilepsy and autism.

  Recruiting Children's Hospital of Fudan University · Shanghai · NCT06668519

• Evaluating cardiovascular events in diabetic patients using HEMOTAG

  This study is testing how well the HEMOTAG device can help track heart problems in people with Type 2 Diabetes who also have other heart risk factors.

  Recruiting Aventusoft, LLC. · West Palm Beach, Florida · NCT06567795

• Care bundle to improve recovery after intracerebral haemorrhage

  This trial will try a structured treatment package—rapid reversal of blood thinners when needed, early intensive blood pressure lowering, and treatment of fever and high blood sugar—to see if it improves 3‑month outcomes for adults with spontaneous intracerebral haemorrhage who arrive within 24 hours of symptom onset.

  Recruiting at 53 sites Phase 4 Region Skane · Oklahoma City, Oklahoma and 53 other locations · NCT06429332

• Improving recovery after surgery for neurocritical care patients

  This study tests a new recovery plan for patients in neurocritical care after surgery to see if it helps them heal faster and have fewer complications compared to standard care.

  Recruiting Shanghai 6th People's Hospital · Shanghai · NCT06241482

• EGb 761 for Mild Cognitive Impairment with Cerebrovascular Disease

  This study is testing if a herbal extract called EGb 761 can help people with Mild Cognitive Impairment and Cerebrovascular Disease improve their thinking and memory over a year.

  Recruiting Phase 2 National Neuroscience Institute · Singapore · NCT04525144

• Assessing the risk of cerebrovascular disease in patients with carotid stenosis

  This study is testing new ways to see if people with asymptomatic carotid stenosis have different thinking skills and stroke risks compared to healthy individuals.

  Recruiting Tang-Du Hospital · Xi'an · NCT04443439

NIH-funded research (24)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Advanced changes in NOTCH3 and brain blood vessel disease

  Researchers are studying how changes in NOTCH3 contribute to brain blood vessel problems that worsen dementia in veterans.

  NIH research Veterans Health Administration · Ann Arbor, United States · NIH-11458591

• Imaging Repository to Advance Cerebrovascular Disease Knowledge

  A patient-friendly imaging data resource is being created to help researchers understand brain blood vessel disorders and improve treatments for stroke and related conditions.

  NIH research Broad Institute, INC. · Cambridge, United States · NIH-11404432

• Midlife heart stress and later brain health

  This project looks at how stress-related changes in blood pressure during midlife may relate to early brain changes linked to dementia.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11397337

• Finding hidden small strokes and white matter damage on routine brain scans with AI

  Using artificial intelligence to spot unnoticed brain blood-vessel damage on routine CT or MRI scans to help people at risk for stroke and dementia.

  NIH research Tufts Medical Center · Boston, United States · NIH-11285315

• How changes in NOTCH3 affect brain blood vessel disease

  Researchers are looking at whether specific changes in the NOTCH3 protein are linked to worse brain blood vessel disease and higher dementia risk, especially among Veterans.

  NIH research Veterans Health Administration · Ann Arbor, United States · NIH-11213915

• Imaging library for stroke and vascular brain disease

  Building a shared collection of brain scans to help researchers better understand and treat stroke and other blood‑vessel problems in the brain.

  NIH research Broad Institute, INC. · Cambridge, United States · NIH-11178352

• Tau buildup and blood vessel disease in Mexican American adults with Alzheimer's

  Using brain PET scans and AI, this project looks for tau protein buildup and cerebrovascular disease in Mexican American adults across the Alzheimer's spectrum to help detect disease earlier and predict memory decline.

  NIH research University of Texas Hlth Science Center · San Antonio, United States · NIH-11169830

• New brain scans and blood tests for small vessel brain disease

  This project tests new brain imaging and blood markers to find and track small vessel brain disease in older adults with memory or thinking problems.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11166308

• Understanding how blood vessel diseases affect memory and thinking skills

  This study is looking at how blood flow problems in the brain might affect thinking skills in people with Alzheimer's disease, using special MRI technology to help doctors understand and improve care for dementia patients over time.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11142202

• Midlife stress-related blood pressure and early brain blood vessel changes

  This project looks at whether people in their 40s–50s who have larger blood pressure spikes during stress show early signs of damage to brain blood vessels.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11141631

• Investigating brain imaging markers in early Alzheimer's disease and cognitive decline

  This study is looking at a tiny part of the brain called the locus coeruleus to see how it changes in older adults, helping us understand the differences between those who age well and those who may develop Alzheimer's or other memory issues.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11088865

• Detecting hidden brain diseases using artificial intelligence

  This study is looking to find hidden brain problems that can lead to strokes and memory issues by using advanced imaging and smart computer technology, so we can help people catch these risks early and stay healthier longer.

  NIH research Tufts Medical Center · Boston, United States · NIH-11035080

• Investigating how mitochondrial dysfunction affects brain health in aging and cerebrovascular disease

  This study is looking at how issues with the tiny powerhouses in our cells, called mitochondria, might play a role in brain diseases like Alzheimer's and other types of dementia, especially after strokes, to help find better ways to prevent or treat these conditions.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11031447

• Understanding small vessel disease and its role in Alzheimer's and related dementias

  This study is looking into how small blood vessel problems in the brain can lead to dementia, like Alzheimer's, by examining brain samples and using advanced imaging techniques to better understand the changes that happen as we age.

  NIH research Washington University · Saint Louis, United States · NIH-11022118

• Investigating how blood vessel health and inflammation affect Alzheimer's in adults with Down syndrome

  This study is looking at how blood vessel problems and inflammation in the brain might affect Alzheimer's disease in adults with Down syndrome, hoping to find helpful information for better treatments and prevention.

  NIH research Columbia University Health Sciences · New York, United States · NIH-10998809

• Investigating tau deposition and cerebrovascular disease in Alzheimer's among Mexican Americans

  This study is looking at how a protein linked to Alzheimer's disease interacts with blood vessel problems in Mexican Americans, using advanced imaging and AI to find early signs of the disease and improve diagnosis, all while focusing on the unique challenges this community faces.

  NIH research University of Texas Hlth Science Center · San Antonio, United States · NIH-10984576

• New ways to detect and monitor small vessel brain disease

  This study is looking at new ways to spot and track small vessel brain problems that can affect memory in older adults, and it's for anyone interested in improving how we diagnose and treat these issues, especially those related to Alzheimer's disease.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10913293

• Creating a database of brain imaging for cerebrovascular diseases

  This study is gathering brain scans from people affected by strokes to learn more about how these conditions develop and improve over time, helping to find better treatments for everyone dealing with cerebrovascular diseases.

  NIH research Broad Institute, INC. · Cambridge, United States · NIH-10907739

• Investigating the impact of dietary compounds on cognitive decline in older adults with diabetes

  This study is looking at how certain foods and substances in the blood, called Advanced Glycation End products (AGEs), might affect memory and thinking skills in older adults with type 2 diabetes, to see if reducing these levels could help prevent dementia.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-10889801

• How midlife stress affects brain health and blood vessels

  This study is looking at how stress affects blood pressure in middle-aged adults and whether that can lead to problems with brain health, like dementia, so we can find ways to help prevent cognitive decline in the future.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10868774

• Early vascular-related thinking and memory changes in CADASIL

  This project looks at how the NOTCH3 (CADASIL) gene leads to early blood-vessel-related thinking and memory changes by following people from before symptoms through dementia.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-10842466

• AI detects hidden brain blood-vessel damage linked to stroke and dementia

  This project uses AI to find hidden small strokes and white-matter changes on routine brain scans in older adults to help prevent future stroke and dementia.

  NIH research Tufts Medical Center · Boston, United States · NIH-10809792

• Using artificial intelligence to find hidden brain diseases that could lead to strokes and dementia

  This study is looking to find hidden brain problems that could lead to stroke or dementia by using smart computer techniques to analyze brain scans and reports, helping doctors catch these issues early and improve treatment for patients.

  NIH research Tufts Medical Center · Boston, United States · NIH-10591063

• Understanding how a genetic condition affects cognitive decline and dementia.

  This study is looking at how blood vessel health affects thinking and memory in people with CADASIL, a rare genetic condition, and it includes both those who have early signs of cognitive issues and those with more advanced symptoms, to help us understand how these problems develop over time.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-10317234

Related topics

Quick answers

How many Cerebrovascular Disease clinical trials are recruiting right now?

14, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in China (7 trials), Italy (2 trials), United States (2 trials), Australia (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2, Phase 2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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