Investigating tau deposition and cerebrovascular disease in Alzheimer's among Mexican Americans
Official title: Cerebral tau deposition and comorbid cerebrovascular disease across the Alzheimer's disease continuum in Mexican Americans
Funded at University of Texas Hlth Science Center · NIH-10984576 · Data updated 2026-11-12
This study is looking at how a protein linked to Alzheimer's disease interacts with blood vessel problems in Mexican Americans, using advanced imaging and AI to find early signs of the disease and improve diagnosis, all while focusing on the unique challenges this community faces.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project start | August 15, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $2,919,399 |
| NIH project number | 1R01AG085571-01A1 |
| Project ID | NIH-10984576 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include Mexican Americans aged 21 and older who are at risk for or diagnosed with Alzheimer's disease or related dementias.
✕Less likely to help
Patients who are not of Mexican descent or those without any risk factors for Alzheimer's disease may not benefit from this research.
What this research studies
This research focuses on understanding how tau deposition, a key factor in Alzheimer's disease, interacts with cerebrovascular disease in Mexican Americans. By utilizing advanced imaging techniques like positron emission tomography (PET) and artificial intelligence (AI), the study aims to identify early signs of Alzheimer's and improve diagnostic accuracy. The research will specifically address the unique challenges faced by the Mexican American population, which is disproportionately affected by Alzheimer's and related dementias. Through this work, the researchers hope to uncover the mechanisms behind these disparities and enhance treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection and tailored treatment options for Alzheimer's disease in Mexican American patients.
How similar studies have gone: Previous research has shown promising results using AI and PET imaging in diverse populations, indicating potential for success in this novel approach.
Where this research is happening
-
University of Texas Hlth Science Center
San Antonio, United States Active
Researchers
- Principal investigator: Habes, Mohamad — University of Texas Hlth Science Center
- Study coordinator: Habes, Mohamad
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.