Assessing the risk of cerebrovascular disease in patients with carotid stenosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the cognitive abilities and cerebrovascular risk in patients with asymptomatic carotid stenosis (ACS) using advanced imaging techniques and cognitive assessments. It will involve comprehensive evaluations including CTA, double modal MRI, and clinical assessments to identify differences in cognitive function and local perfusion between ACS patients and healthy individuals. The study seeks to develop noninvasive methods for predicting the risk of ischemic stroke in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Mild stenosis group: CTA suggested carotid stenosis \< 30%;
2. Moderate stenosis group: CTA suggested carotid stenosis of 30-69%;
3. Severe stenosis group: CTA indicated carotid stenosis ≥70%;

Exclusion Criteria:

1. dementia, MMSE score \< 21;
2. previous carotid stenosis related neurological symptoms or transient ischemic attack;
3. other craniocerebral lesions, such as craniocerebral trauma, tumor, inflammation, and complications of great vessels (cerebral infarction or cerebral malacia);
4. contraindications for MRI examination;
5. recent use of psychoactive drugs or hormones.

Where it's running

• Wen Wang
  Xi'an, China Recruiting

Study contacts

• Study coordinator: Wen Wang, Ph.D.
• Email: wangwen@fmmu.edu.cn
• Phone: +8618629066628

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.