Improving recovery after surgery for neurocritical care patients

A Randomized Controlled Clinical Study on Safety and Efficacy of Enhanced Recovery After Surgery in Neurocritical Care Patients

Not applicable Interventional Shanghai 6th People's Hospital · NCT06241482

This study tests a new recovery plan for patients in neurocritical care after surgery to see if it helps them heal faster and have fewer complications compared to standard care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment80 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorShanghai 6th People's Hospital Academic / other
Locations1 site (Shanghai)
Trial IDNCT06241482 on ClinicalTrials.gov

What this trial studies

This study evaluates the safety and efficacy of an Enhanced Recovery After Surgery (ERAS) protocol specifically designed for patients in neurocritical care, including those with traumatic brain injury and cerebrovascular disease. The ERAS approach focuses on optimizing perioperative management to reduce complications, promote faster recovery, and decrease hospital stays. By implementing evidence-based practices, the study aims to enhance patient outcomes in neurosurgical intensive care settings. The research will compare the ERAS protocol to conventional therapy to assess its effectiveness.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18-75 with moderate to severe acute traumatic brain injury or cerebrovascular disease requiring intensive care.

Not a fit: Patients undergoing non-surgical treatment or those diagnosed as brain dead shortly after admission will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve recovery times and outcomes for patients undergoing neurosurgery.

How similar studies have performed: While ERAS has been successful in various surgical fields, its application in neurosurgery is relatively novel and underexplored.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18-75 years old
* Patients with moderate or severe acute traumatic brain injury or cerebrovascular disease requiring neurosurgical intensive care treatment
* Hospitalization time ≥ 1 week
* The guardian is able to understand and actively cooperate in completing the project
* The guardian signs an informed consent form

Exclusion Criteria:

* Patients undergoing non-surgical treatment
* Patients diagnosed as brain death within the first 24 hours after admission to NICU
* Patients undergoing cardiopulmonary resuscitation, maintenance dialysis, end-stage tumors, and disseminated cancer
* Patients who withdraw treatment during hospitalization or are discharged automatically
* Patients who underwent unplanned secondary surgery during the research process
* Individuals who cannot be followed up during the research process

Where this trial is running

Shanghai

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Neurocritical CareTraumatic Brain InjuryCerebrovascular DiseaseModerate or Severe Coma
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.