Condition

Borderline Personality Disorder clinical trials and research

• 28Clinical trials
• 3NIH research projects
• 11Countries

Newest Borderline Personality Disorder clinical trials

All recruiting trials (28)

• Long-term outcomes after MBT for borderline personality disorder

  This long-term follow-up checks how people with borderline personality disorder who received MBT in the past are doing more than 10 years later and whether the two MBT formats differ in long-term outcomes.

  Recruiting at 2 sites De Viersprong · Amsterdam and 1 other locations · NCT07509216

• See if Borderline Personality Disorder can be viewed as a Relationship-Use Disorder

  Researchers are testing whether BPD symptoms reflect an addiction-like reliance on interpersonal relationships, compared with bipolar disorder and healthy controls.

  Recruiting University Hospital, Montpellier · Montpellier · NCT07337889

• rTMS (noninvasive brain stimulation) for borderline personality disorder

  This project will try rTMS brain stimulation to see if it reduces symptoms in adults with borderline personality disorder.

  Recruiting at 2 sites University of California, Los Angeles · Los Angeles, California and 1 other locations · NCT07197502

• Evaluating a new treatment approach for borderline personality disorder

  This study is testing a new personalized treatment for borderline personality disorder to see if it works better than the standard approach.

  Recruiting at 2 sites AddiPsy · Bayonne and 1 other locations · NCT06913738

• Physical activity for people with schizophrenia, borderline personality disorder, or vestibular disorders

  This study tests whether a tailored physical activity program helps people with schizophrenia, borderline personality disorder, or vestibular disorders improve activity adherence and well‑being.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT06817980

• Training to improve emotion regulation in people with Borderline Personality Disorder

  This study is testing a new training program to help people with Borderline Personality Disorder learn better ways to manage their emotions.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06772831

• MDMA to improve social understanding in borderline personality disorder

  This trial will test whether MDMA can improve social thinking and relationships in adults with borderline personality disorder.

  Recruiting Phase 2 Yale University · New Haven, Connecticut · NCT06683014

• Training brain signals to help manage emotions in Borderline Personality Disorder

  This study is testing if training brain signals can help people with Borderline Personality Disorder manage their emotions better.

  Recruiting at 5 sites Phase 1/2 Central Institute of Mental Health, Mannheim · Freiburg im Breisgau and 5 other locations · NCT06626789

• Group schema therapy for adolescents with borderline symptoms

  This program will test whether group schema therapy using self-recorded video exercises helps adolescents aged 15–18 with borderline symptoms compared with usual care.

  Recruiting Turku University Hospital · Turku, Southwest Finland · NCT06606002

• Improving treatment for patients with borderline personality disorder

  This study is testing a new treatment approach for people with borderline personality disorder to see if adding case management and family meetings helps them feel better compared to standard care.

  Recruiting University Hospital Bispebjerg and Frederiksberg · Copenhagen · NCT06563466

• EMDR therapy for adults with borderline personality disorder

  This trial will try EMDR, a trauma-focused psychotherapy, to reduce symptoms in adults with borderline personality disorder, particularly those with a history of early-life trauma or PTSD.

  Recruiting Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · Brescia, Brescia · NCT06493708

• Partner-inclusive therapy for borderline personality disorder

  This project tests whether adding partner-focused therapy to usual care helps adults with borderline personality disorder and their romantic partners.

  Recruiting Phase 2 York University · Toronto, California · NCT06458933

• Investigating factors affecting treatment outcomes in Dialectical Behavior Therapy for Borderline Personality Disorder

  This study is trying to find out what factors affect how well Dialectical Behavior Therapy works for people with Borderline Personality Disorder and a history of self-harm.

  Recruiting Region Skane · Lund, Skåne County · NCT06106555

• Comparing Mentalization-Based Treatment and Standard Therapy for Borderline Personality Disorder in Germany

  This study is testing if a new type of therapy called Mentalization-Based Treatment can help people with Borderline Personality Disorder in Germany feel better and have fewer crises compared to standard therapy options.

  Recruiting at 2 sites Heidelberg University · Berlin and 4 other locations · NCT06018272

• Comparing brain stimulation techniques for impulsivity in borderline personality disorder

  This study is testing a new brain stimulation technique to see if it can help people with borderline personality disorder reduce their impulsivity.

  Recruiting Hôpital le Vinatier · Bron, AURA · NCT05942651

• Short therapy program for young adults with borderline personality disorder

  This study is testing a new 10-week therapy program for young adults with borderline personality disorder to see if it can help reduce impulsive behaviors and improve their overall well-being.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT05913544

• Survey to determine eligibility for psychiatry clinical trials

  This study is trying to see if people with conditions like depression, anxiety, or personality disorders can join upcoming psychiatry clinical trials.

  Recruiting at 6 sites Adams Clinical · Boston, Massachusetts and 5 other locations · NCT05800925

• Combining neurostimulation with emotion regulation training for emotional issues

  This study is testing if combining brain stimulation with training on how to manage emotions can help people with emotional issues feel better.

  Recruiting Duke University · Durham, North Carolina · NCT05712057

• Compassion-focused therapy for reducing self-stigma in mental health disorders

  This study is testing whether Compassion Focused Therapy can help people with mental health disorders feel better about themselves and reduce feelings of shame.

  Recruiting University Hospital, Strasbourg, France · Bordeaux and 6 other locations · NCT05698589

• Personalized emotion regulation skills training

  This study is testing if teaching people personalized ways to manage their emotions can help them feel less negative every day compared to using standard methods.

  Recruiting Ohio State University · Columbus, Ohio · NCT05651295

• Effects of exercise on patients with borderline personality disorder

  This study tests how one session of different levels of exercise can help people with borderline personality disorder manage stress and improve their thinking and emotions.

  Recruiting University Hospital, Bonn · Bonn, North Rhine-Westphalia · NCT05246527

• Treatment for depression in borderline personality disorder using brain stimulation

  This study is testing if a special type of brain stimulation can help people with borderline personality disorder and depression feel better.

  Recruiting Stanford University · Stanford, California · NCT04870255

• Brain MRI of teenage girls with borderline personality disorder, with and without PTSD

  This project will use MRI scans to see if hippocampus size and other brain measures differ between adolescent girls with borderline personality disorder who do and do not have PTSD.

  Recruiting University Hospital, Caen · Caen · NCT04852744

• Understanding predictors of treatment response in Dialectical Behaviour Therapy for self-harm and borderline personality disorder

  This study is trying to find out what factors help predict how well Dialectical Behaviour Therapy works for people with self-harm and borderline personality disorder.

  Recruiting at 5 sites Oslo University Hospital · Oslo, Oslo and 4 other locations · NCT04318899

• Using brain stimulation to improve thinking skills in people with mental health conditions

  This study is testing if a brain stimulation treatment can help improve thinking skills in people with mental health conditions like depression, bipolar disorder, and ADHD.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT04296604

• Understanding shame's role in suicidal behavior in Borderline Personality Disorder

  This study looks at how feelings of shame might be linked to suicidal behavior in people with Borderline Personality Disorder to see if understanding this connection can help identify those at risk.

  Recruiting University Hospital, Montpellier · Montpellier, Hérault · NCT03994510

• Understanding emotional dysregulation in self-harm behaviors

  This study is testing if Dialectical Behavior Therapy can help people who self-harm by improving their emotional control and reducing the frequency and intensity of their self-injury.

  Recruiting Haukeland University Hospital · Bergen · NCT03846375

• A new medication for treating Borderline Personality Disorder

  This study is testing a new medication to see if it can help people with Borderline Personality Disorder feel better and manage their emotions more effectively.

  Recruiting Phase 2 The Alfred · Melbourne, Victoria · NCT02097706

NIH-funded research (3)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding how early life patterns lead to Borderline Personality Disorder later on

  This research looks at how children with emotional and social difficulties may develop Borderline Personality Disorder as they grow into young adults.

  NIH research Washington University · Saint Louis, United States · NIH-11321100

• Understanding suicidal crises in borderline personality disorder

  This project aims to better predict and prevent suicidal thoughts and attempts in people with borderline personality disorder using long-term follow-up, daily symptom tracking, and decision-making tests.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11266150

• Mindfulness Neurofeedback to Enhance Therapy for Borderline Personality Disorder

  This project explores if a special brain training called mindfulness neurofeedback can make Dialectical Behavior Therapy (DBT) even more helpful for adults with Borderline Personality Disorder.

  NIH research Yale University · New Haven, United States · NIH-11175460

Related topics

Quick answers

How many Borderline Personality Disorder clinical trials are recruiting right now?

28, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in United States (8 trials), France (8 trials), Germany (3 trials), Norway (2 trials), Sweden (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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