Understanding shame's role in suicidal behavior in Borderline Personality Disorder

Study of Shame Propensity as a Prognostic Factor of Suicidal Behaviors in Patients With Borderline Personality Disorder

Not applicable Interventional University Hospital, Montpellier · NCT03994510

This study looks at how feelings of shame might be linked to suicidal behavior in people with Borderline Personality Disorder to see if understanding this connection can help identify those at risk.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment688 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Hospital, Montpellier Academic / other
Locations1 site (Montpellier, Hérault)
Trial IDNCT03994510 on ClinicalTrials.gov

What this trial studies

This study investigates the relationship between shame and suicidal behavior in patients diagnosed with Borderline Personality Disorder (BPD). Over a five-year period, 688 participants will be followed to assess their propensity to feel shame and its predictive value for suicide attempts. The study includes annual clinical evaluations and self-questionnaires, along with genetic and biological sample collections. The goal is to identify subgroups of patients based on their suicidal behavior and overall functioning, as well as to discover biological markers that may predict suicide attempts.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 with a clinical diagnosis of Borderline Personality Disorder.

Not a fit: Patients who are currently incarcerated or under guardianship may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and prevention strategies for suicidal behavior in patients with Borderline Personality Disorder.

How similar studies have performed: Other studies have explored the relationship between emotional factors and suicidal behavior, suggesting that this approach may yield valuable insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion criteria:

* To be over 18
* Clinical diagnosis of BPD using the SCID II (Structured Clinical Interview for DSM-IV-Text Reviewed Axis II Personality Disorders)
* Having signed the informed consent
* Able to understand the nature, the purpose and the methodology of the study
* Able to understand and perform the clinical evaluations

Exclusion criteria:

* Deprived of liberty (by judicial or administrative decision)
* Protected by law (guardianship)
* Exclusion period in relation to another protocol
* Not affiliated to a social security scheme

Where this trial is running

Montpellier, Hérault

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Borderline Personality DisorderPsychiatrySuicidal BehaviorFollow-Up Study
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.