Understanding predictors of treatment response in Dialectical Behaviour Therapy for self-harm and borderline personality disorder
Official title: Predictors of Clinical Course and Treatment Response in Patients Having Received Dialectical Behaviour Therapy Delivered by Clinical Units in the Norwegian Network for Clinical Evaluation and Quality in DBT Programmes
Run by Oslo University Hospital · NCT04318899 · Data updated 2026-11-12
This study is trying to find out what factors help predict how well Dialectical Behaviour Therapy works for people with self-harm and borderline personality disorder.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 12 Years to 70 Years |
| Sex | All |
| Enrollment | 250 (estimated) |
| Sponsor | Oslo University Hospital Academic / other |
| Locations | 5 sites (Oslo, Oslo and 4 other locations) |
| Status | Recruiting |
| Started | January 1, 2018 |
| Main results expected | December 31, 2029 |
| Study ends | December 31, 2029 |
| Registry record updated | October 16, 2026 |
| Trial ID | NCT04318899 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals with a history of repeated deliberate self-harm and a diagnosis of borderline personality disorder.
✕Probably not a fit
Patients with psychotic disorders, anorexia nervosa, substance dependence disorder, or autism may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project collaborates with various clinical units in Norway to establish a platform for delivering and evaluating Dialectical Behaviour Therapy (DBT) for patients with self-harm and borderline personality disorder. It aims to systematically collect data on patient characteristics and treatment outcomes to identify predictors of clinical course and response to therapy. The study will analyze factors such as sociodemographic variables, psychiatric diagnoses, and previous treatment history to understand their impact on treatment effectiveness. By utilizing a uniform protocol for assessments, the research seeks to enhance the quality of DBT and improve patient care.
Why it matters
Potential benefit: If successful, this study could lead to more personalized and effective treatment strategies for patients with borderline personality disorder and self-harming behaviors.
How similar studies have gone: Other studies have shown success in using DBT for similar conditions, indicating that this approach is both tested and promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * History of repeated deliberate self harm * Satisfies criteria of Diagnostic and Statistical Manual (DSM-IV) Borderline Personality Disorder as measured by Structured Clinical Interview for the DSM (SCID-II) in addition to the self-destructive criterion. Exclusion Criteria: * Psychotic disorders * Anorexia Nervosa * Substance dependence disorder * Mental retardation (IQ less than 70) * Asperger syndrome/autism
Where it's running
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Søndre Oslo DPS/Oslo Universitetssykehus HF
Oslo, Oslo, Norway Recruiting -
Moss DPS/Østfold sykehus HF
Moss, Norway Recruiting -
Psykiatrisk senter ytre Helgeland/Helgelandssykehuset HF
Sandnessjøen, Norway Recruiting -
Bjerketun behandlingshjem/Vestreviken HF
Sandvika, Norway Recruiting -
BUP Lian/St Olavs Hospital HF
Trondheim, Norway Recruiting
Study contacts
- Principal investigator: Lars Mehlum, MD PhD — University of Oslo
- Study coordinator: Egil Haga, PhD
- Email: egil.haga@medisin.uio.no
- Phone: +4722923442
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.