NIH-funded research NIH-funded research

Mindfulness Neurofeedback to Enhance Therapy for Borderline Personality Disorder

Official title: Mindfulness-based Neurofeedback to augment DBT psychotherapy for adults with Borderline Personality Disorder (MIND-BPD)

Funded at Yale University · NIH-11175460 · Data updated 2026-11-12

This project explores if a special brain training called mindfulness neurofeedback can make Dialectical Behavior Therapy (DBT) even more helpful for adults with Borderline Personality Disorder.

More Mindfulness research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startSeptember 1, 2024
Project endMay 31, 2027
Funding year2025
Award (this year)$1,179,243
NIH project number5R61MH135009-02
Project IDNIH-11175460 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults aged 21 and older who have Borderline Personality Disorder and are interested in participating in both neurofeedback and DBT skills group training.

Less likely to help

Patients who do not have Borderline Personality Disorder or are unable to participate in mindfulness meditation or neurofeedback may not receive benefit from this specific approach.

What this research studies

This project is a clinical trial for adults with Borderline Personality Disorder (BPD) that combines a special brain training called mindfulness-based neurofeedback (mbNF) with Dialectical Behavior Therapy (DBT) skills groups. During mbNF, you would practice mindfulness meditation while receiving real-time feedback on your brain activity, helping you learn to focus your mind better. The goal is to strengthen the brain areas involved in mindfulness, which could make DBT more effective. We hope this combination will lead to greater benefits than DBT skills groups alone.

Why it matters

Potential benefit: If successful, this approach could make an established therapy for Borderline Personality Disorder more effective and potentially less intensive for patients.

How similar studies have gone: Previous studies using mindfulness-based neurofeedback have shown promising results in decreasing certain brain activity patterns, suggesting a foundation for this approach.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Fineberg, Sarah K — Yale University
  • Study coordinator: Fineberg, Sarah K

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.