rTMS (noninvasive brain stimulation) for borderline personality disorder

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind study will enroll up to 30 adults diagnosed with borderline personality disorder. Participants are assigned to active or sham rTMS and may receive up to 30 stimulation sessions over about 2.5 months, with sham participants offered an additional 15 active sessions. Study procedures include up to two MRI scans, two EEG recordings, computerized symptom assessments and cognitive tasks targeting impulsivity and emotion regulation, and require a minimum of 17 in-person visits; consent is completed remotely via Zoom. Outcomes will compare changes in BPD, depression, and anxiety symptom scales as well as neurobehavioral measures between groups.

Why it matters

Who can join: the full rules

* Age of 18-65
* DSM-5 Diagnosis of BPD based upon a psychiatric evaluation and ZAN-BPD
* Fluent English speaker
* Signed informed consent

Where it's running

• Semel Institute for Neuroscience and Human Behavior at UCLA
  Los Angeles, California, United States Recruiting
• Semel Institute/ UCLA TMS
  Los Angeles, California, United States Recruiting

Study contacts

• Study coordinator: Elizabeth Pinkerton
• Email: EPinkerton@mednet.ucla.edu
• Phone: 310-794-0331

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.