Physical activity for people with schizophrenia, borderline personality disorder, or vestibular disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial explores whether a standard physical activity program can be feasible and beneficial for adults with schizophrenia, borderline personality disorder, or vestibular disorders who have BMI under 40. The researchers plan to first measure self-perception and bodily sense of self related to movement, then implement a physical activity intervention. The study design incorporates stagewise assessment to understand how body awareness might influence engagement in exercise. Participants will be adults aged 18 to 60, with specific DSM-5 diagnoses confirmed, and able to consent and comply with vision and safety criteria. The trial will be conducted at the University Hospital in Strasbourg, with no listed collaborators.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Criteria common to all participants:
* Men or women aged 18 to 60 inclusive
* Subject affiliated to a health insurance scheme, beneficiary or beneficiary's beneficiary
* Able to understand the aims and risks of the research, and to give informed consent
* Visual acuity \> 0.7 on the Freiburg Vision Test (Bach 1996) due to the use of visual equipment
* BMI (body mass index) \< 40 (due to cardiovascular risk).

Patient-specific criteria:

* With schizophrenia: criteria for schizophrenia as defined in the DSMV (American Psychiatric Association, 2015)
* With borderline personality disorder: criteria for borderline personality disorder as defined in the DSMV (American Psychiatric Association, 2015)
* With vestibular disorders: peripheral vestibular disorders established after otolaryngological examination

Exclusion Criteria:

* Criteria common to all participants:
* Serious or unstabilized somatic pathology (including cardiovascular)
* History likely to affect cerebral anatomy or to be linked to an abnormality (neonatal suffering, neurosurgical operation, comitiality, stroke...)
* Presence of joint pain, likely to worsen after exercise
* \- Substance use disorders (as defined by DSM-IV TR)
* 3D vision disorders as measured by the Wirt stereotest (depth perception at a disparity of at least 80'' arc)
* Movement perception disorders (correct movement discrimination in less than 75% of trials (cf. § V-2.2)
* History of general anaesthesia in the 3 months preceding the study
* History of neurological disease
* Impossibility of giving the subject informed information (subject in emergency situation)
* Pregnancy declared by patient
* Breast-feeding
* Subject in exclusion period (determined by a previous or current study)
* Subject hospitalized
* Subject under court protection

Exclusion criteria specific to control subjects or patients with vestibular syndrome:

History of major psychiatric pathology with current psychotropic medication (i.e., antidepressant, thymoregulator, antipsychotic)

Where it's running

• Service de psychiatrie
  Strasbourg, France Recruiting

Study contacts

• Study coordinator: Sarah Hustache
• Email: dpidrci@chru-strasbourg.fr
• Phone: 0388116768

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Cognitive Tasks and Models in a Large Online Sample

  This study tests cognitive tasks and computational models in a large online group to see if these tools can help predict symptoms like hallucinations and delusions in the general population.

  Recruiting at 2 sites Washington University School of Medicine · Minneapolis, Minnesota and 1 other locations · NCT07900893

• Can seven tasks help distinguish schizophrenia and schizoaffective disorder from healthy people

  The study tests seven cognitive tasks to see if they can tell apart people with schizophrenia or schizoaffective disorder from healthy adults and predict symptoms like hallucinations and delusions.

  Recruiting at 5 sites Washington University School of Medicine · Irvine, California and 4 other locations · NCT07853807

• See if an early-detection program reduces time to treatment for first-episode psychosis

  We test whether a large, region-wide early-detection program can shorten the time from first psychotic symptoms to treatment and help people function better later.

  Recruiting at 2 sites Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital · Copenhagen, Denmark and 1 other locations · NCT07716969

• Gamma brain-feedback to boost working memory in schizophrenia

  This trial tests whether real-time gamma EEG neurofeedback helps people with schizophrenia or schizoaffective disorder improve working memory.

  Recruiting Phase 2 University of California, San Diego · La Jolla, California · NCT07592169

• Long-term outcomes after MBT for borderline personality disorder

  This long-term follow-up checks how people with borderline personality disorder who received MBT in the past are doing more than 10 years later and whether the two MBT formats differ in long-term outcomes.

  Recruiting at 2 sites De Viersprong · Amsterdam and 1 other locations · NCT07509216

• tDCS targeting the brain's motion-processing pathway (MT+) to improve emotion recognition

  See if personalized, MR-guided tDCS over the motion-processing area of the brain can improve face emotion recognition in adults with schizophrenia or schizoaffective disorder.

  Recruiting Nathan Kline Institute for Psychiatric Research · Orangeburg, New York · NCT07469384

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.