Effects of exercise on patients with borderline personality disorder

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project investigates how a single session of physical exercise impacts stress regulation, cognitive and emotional functioning in patients with borderline personality disorder (BPD). The study aims to determine the optimal intensity of exercise (moderate vs. high) and assess changes in behavioral measures and biomarkers through saliva and blood samples. By exploring the relationship between acute exercise and BPD symptoms, the researchers hope to provide insights into non-pharmacological treatment options for this condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* estimated verbal intelligence quotient \>80 (MWT-B; Lehrl 2005)
* patients: diagnosis of borderline personality disorder according to DSM-5

Exclusion Criteria:

* neurological disorders
* health conditions interfering with exercise safety, e.g. coronary heart disease
* visual impairments that may interfere with performance of the cognitive tasks
* endocrine disorders, e.g. hyperthyreosis or diabetes mellitus;
* following psychiatric disorders: psychosis or affective disorders with psychotic symptoms, schizophrenia, substance abuse or dependence, autism spectrum disorders, anorexia nervosa;
* healthy controls: BPD, intake of psychotropic drugs

Where it's running

• University Hospital Bonn
  Bonn, North Rhine-Westphalia, Germany Recruiting

Study contacts

• Study coordinator: Aylin Mehren, Dr.
• Email: aylin.mehren@ukbonn.de
• Phone: +4922828731370

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Long-term outcomes after MBT for borderline personality disorder

  This long-term follow-up checks how people with borderline personality disorder who received MBT in the past are doing more than 10 years later and whether the two MBT formats differ in long-term outcomes.

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• See if Borderline Personality Disorder can be viewed as a Relationship-Use Disorder

  Researchers are testing whether BPD symptoms reflect an addiction-like reliance on interpersonal relationships, compared with bipolar disorder and healthy controls.

  Recruiting University Hospital, Montpellier · Montpellier · NCT07337889

• rTMS (noninvasive brain stimulation) for borderline personality disorder

  This project will try rTMS brain stimulation to see if it reduces symptoms in adults with borderline personality disorder.

  Recruiting at 2 sites University of California, Los Angeles · Los Angeles, California and 1 other locations · NCT07197502

• Evaluating a new treatment approach for borderline personality disorder

  This study is testing a new personalized treatment for borderline personality disorder to see if it works better than the standard approach.

  Recruiting at 2 sites AddiPsy · Bayonne and 1 other locations · NCT06913738

• Physical activity for people with schizophrenia, borderline personality disorder, or vestibular disorders

  This study tests whether a tailored physical activity program helps people with schizophrenia, borderline personality disorder, or vestibular disorders improve activity adherence and well‑being.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT06817980

• Training to improve emotion regulation in people with Borderline Personality Disorder

  This study is testing a new training program to help people with Borderline Personality Disorder learn better ways to manage their emotions.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06772831

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.