Effects of exercise on patients with borderline personality disorder
Acute Effects of Physical Exercise in Patients with Borderline Personality Disorder
This study tests how one session of different levels of exercise can help people with borderline personality disorder manage stress and improve their thinking and emotions.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | University Hospital, Bonn Academic / other |
| Locations | 1 site (Bonn, North Rhine-Westphalia) |
| Trial ID | NCT05246527 on ClinicalTrials.gov |
What this trial studies
This project investigates how a single session of physical exercise impacts stress regulation, cognitive and emotional functioning in patients with borderline personality disorder (BPD). The study aims to determine the optimal intensity of exercise (moderate vs. high) and assess changes in behavioral measures and biomarkers through saliva and blood samples. By exploring the relationship between acute exercise and BPD symptoms, the researchers hope to provide insights into non-pharmacological treatment options for this condition.
Who should consider this trial
Good fit: Ideal candidates are individuals diagnosed with borderline personality disorder who have a verbal IQ above 80.
Not a fit: Patients with neurological disorders, severe health conditions, or other psychiatric disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could offer a new, effective non-drug intervention for managing symptoms of borderline personality disorder.
How similar studies have performed: While previous studies suggest a positive influence of physical exercise on BPD symptoms, this specific investigation into acute exercise effects is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * estimated verbal intelligence quotient \>80 (MWT-B; Lehrl 2005) * patients: diagnosis of borderline personality disorder according to DSM-5 Exclusion Criteria: * neurological disorders * health conditions interfering with exercise safety, e.g. coronary heart disease * visual impairments that may interfere with performance of the cognitive tasks * endocrine disorders, e.g. hyperthyreosis or diabetes mellitus; * following psychiatric disorders: psychosis or affective disorders with psychotic symptoms, schizophrenia, substance abuse or dependence, autism spectrum disorders, anorexia nervosa; * healthy controls: BPD, intake of psychotropic drugs
Where this trial is running
Bonn, North Rhine-Westphalia
- University Hospital Bonn — Bonn, North Rhine-Westphalia, Germany (Recruiting)
Study contacts
- Study coordinator: Aylin Mehren, Dr.
- Email: aylin.mehren@ukbonn.de
- Phone: +4922828731370
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.